In medical healthcare, obtaining detailed annotations is challenging, highlighting the need for robust Vision-Language Models (VLMs). Pretrained VLMs enable fine-tuning on small datasets or zero-shot inference, achieving performance comparable to task-specific models. Contrastive learning (CL) is a key paradigm for training VLMs but inherently requires large batch sizes for effective learning, making it computationally demanding and often limited to well-resourced institutions. Moreover, with limited data in healthcare, it is important to prioritize knowledge extraction from both data and models during training to improve performance. Therefore, we focus on leveraging the momentum method combined with distillation to simultaneously address computational efficiency and knowledge exploitation. Our contributions can be summarized as follows: (1) leveraging momentum self-distillation to enhance multimodal learning, and (2) integrating momentum mechanisms with gradient accumulation to enlarge the effective batch size without increasing resource consumption. Our method attains competitive performance with state-of-the-art (SOTA) approaches in zero-shot classification, while providing a substantial boost in the few-shot adaption, achieving over 90% AUC-ROC and improving retrieval tasks by 2-3%. Importantly, our method achieves high training efficiency with a single GPU while maintaining reasonable training time. Our approach aims to advance efficient multimodal learning by reducing resource requirements while improving performance over SOTA methods. The implementation of our method is available at https://github.com/phphuc612/MSD .

As a representative optic degenerative condition, glaucoma has been a threat to millions due to its irreversibility and severe impact on human vision fields. Mainly characterized by dimmed and blurred visions, or peripheral vision loss, glaucoma is well known to occur due to damages in the optic nerve from increased intraocular pressure (IOP) or neovascularization within the retina. Traditionally, most glaucoma related works and clinical diagnosis focused on detecting these damages in the optic nerve by using patient data from perimetry tests, optic papilla inspections and tonometer-based IOP measurements. Recently, with advancements in computer vision AI models, such as VGG16 or Vision Transformers (ViT), AI-automatized glaucoma detection and optic cup segmentation based on retinal fundus images or OCT recently exhibited significant performance in aiding conventional diagnosis with high performance. However, current AI-driven glaucoma detection approaches still have significant room for improvement in terms of reliability, excessive parameter usage, possibility of spurious correlation within detection, and limitations in applications to intervention analysis or clinical simulations. Thus, this research introduced a novel causal representation driven glaucoma detection model: LightHCG, an extremely lightweight Convolutional VAE-based latent glaucoma representation model that can consider the true causality among glaucoma-related physical factors within the optic nerve region. Using HSIC-based latent space disentanglement and Graph Autoencoder based unsupervised causal representation learning, LightHCG not only exhibits higher performance in classifying glaucoma with 93~99% less weights, but also enhances the possibility of AI-driven intervention analysis, compared to existing advanced vision models such as InceptionV3, MobileNetV2 or VGG16.

Prediction markets allow users to trade on outcomes of real-world events, but are prone to fragmentation with overlapping questions, implicit equivalences, and hidden contradictions across markets. We present an agentic AI pipeline that autonomously (i) clusters markets into coherent topical groups using natural-language understanding over contract text and metadata, and (ii) identifies within-cluster market pairs whose resolved outcomes exhibit strong dependence, including "same-outcome" (correlated) and "different-outcome" (anti-correlated) relationships. Using a historical dataset of resolved markets on Poly-market, we evaluate the accuracy of the agent's relational predictions. We then synthesize discovered relationships into a simple trading strategy to quantify how discovered relationships translate into actionable strategies. Results show that agent-identified relationships have around 60-70% accuracy, and their induced trading strategies have an average return of 20% over week-long horizons, highlighting the ability of agen-tic AI and large language models to uncover latent semantic structure within prediction markets.

Recent advances in general-purpose AI systems with attention-based transformers offer a potential window into how the neocortex and cerebellum, despite their relatively uniform circuit architectures, give rise to diverse functions and, ultimately, to human intelligence. This Perspective provides a cross-domain comparison between the brain and AI that goes beyond the traditional focus on visual processing, adopting the emerging perspecive of world-model-based computation. Here, we identify shared computational mechanisms in the attention-based neocortex and the non-attentional cerebellum: both predict future world events from past inputs and construct internal world models through prediction-error learning. These predictive world models are repurposed for seemingly distinct functions -- understanding in sensory processing and generation in motor processing -- enabling the brain to achieve multi-domain capabilities and human-like adaptive intelligence. Notably, attention-based AI has independently converged on a similar learning paradigm and world-model-based computation. We conclude that these shared mechanisms in both biological and artificial systems constitute a core computational foundation for realizing diverse functions including high-level intelligence, despite their relatively uniform circuit structures. Our theoretical insights bridge neuroscience and AI, advancing our understanding of the computational essence of intelligence.

World models have gained significant attention as a promising approach for autonomous driving. By emulating human-like perception and decision-making processes, these models can predict and adapt to dynamic environments. Existing methods typically map high-dimensional observations into compact latent spaces and learn optimal policies within these latent representations. However, prior work usually jointly learns ego-vehicle dynamics and environmental transition dynamics from the image input, leading to inefficiencies and a lack of robustness to variations in vehicle dynamics. To address these issues, we propose the Vehicle Dynamics embedded Dreamer (VDD) method, which decouples the modeling of ego-vehicle dynamics from environmental transition dynamics. This separation allows the world model to generalize effectively across vehicles with diverse parameters. Additionally, we introduce two strategies to further enhance the robustness of the learned policy: Policy Adjustment during Deployment (PAD) and Policy Augmentation during Training (PAT). Comprehensive experiments in simulated environments demonstrate that the proposed model significantly improves both driving performance and robustness to variations in vehicle dynamics, outperforming existing approaches.

Abstract--The emergence of Large Language Models (LLMs) is rapidly accelerating the development of autonomous multi-agent systems (MAS), paving the way for the Internet of Agents. However, traditional centralized MAS architectures present significant challenges, including single points of failure, vulnerability to censorship, inherent scalability limitations, and critical trust issues. We propose a novel Decentralized Multi-Agent System (DMAS) architecture designed to overcome these fundamental problems by enabling trust-aware, scalable, and censorship-resistant interactions among autonomous agents. Our DMAS features a decentralized agent runtime underpinned by a blockchain-based architecture. We formalize a trust-aware communication protocol that leverages cryptographic primitives and on-chain operations to provide security properties: verifiable interaction cycles, communication integrity, authenticity, non-repudiation, and conditional confidentiality, which we further substantiate through a comprehensive security analysis. The rapid advancements in Large Language Models (LLMs) [1]-[4] have opened unprecedented avenues for creating highly autonomous and intelligent agents. These LLM-augmented agents possess remarkable capabilities in understanding natural language, performing complex reasoning, planning intricate sequences of actions, and engaging in sophisticated communication.

With the advancement of natural language generation (NLG) technologies, creative story generation systems have gained increasing attention. However, current systems often fail to accurately translate user intent into satisfactory story outputs due to a lack of fine-grained control and unclear input specifications, limiting their applicability. To address this, we propose TaleFrame, a system that combines large language models (LLMs) with human-computer interaction (HCI) to generate stories through structured information, enabling precise control over the generation process. The innovation of TaleFrame lies in decomposing the story structure into four basic units: entities, events, relationships, and story outline. We leverage the Tinystories dataset, parsing and constructing a preference dataset consisting of 9,851 JSON-formatted entries, which is then used to fine-tune a local Llama model. By employing this JSON2Story approach, structured data is transformed into coherent stories. TaleFrame also offers an intuitive interface that supports users in creating and editing entities and events and generates stories through the structured framework. Users can control these units through simple interactions (e.g., drag-and-drop, attach, and connect), thus influencing the details and progression of the story. The generated stories can be evaluated across seven dimensions (e.g., creativity, structural integrity), with the system providing suggestions for refinement based on these evaluations. Users can iteratively adjust the story until a satisfactory result is achieved. Finally, we conduct quantitative evaluation and user studies that demonstrate the usefulness of TaleFrame. Dataset available at https://huggingface.co/datasets/guodaosun/tale-frame.

Agentic systems are modern software systems: they consist of orchestrated modules, expose interfaces, and are deployed in software pipelines. Unlike conventional programs, their execution (i.e., trajectories) is inherently stochastic and adaptive to the problem they are solving. Evaluation of such systems is often outcome-centric, judging their performance based on success or failure at the final step. This narrow focus overlooks detailed insights about such systems, failing to explain how agents reason, plan, act, or change their strategies over time. Inspired by the structured representation of conventional software systems as graphs, we introduce Graphectory to systematically encode the temporal and semantic relations in such software systems. Graphectory facilitates the design of process-centric metrics and analyses to assess the quality of agentic workflows independent of final success. Using Graphectory, we analyze 4000 trajectories of two dominant agentic programming workflows, namely SWE-agent and OpenHands, with a combination of four backbone Large Language Models (LLMs), attempting to resolve SWE-bench Verified issues. Our fully automated analyses reveal that: (1) agents using richer prompts or stronger LLMs exhibit more complex Graphectory, reflecting deeper exploration, broader context gathering, and more thorough validation before patch submission; (2) agents' problem-solving strategies vary with both problem difficulty and the underlying LLM -- for resolved issues, the strategies often follow coherent localization-patching-validation steps, while unresolved ones exhibit chaotic, repetitive, or backtracking behaviors; (3) even when successful, agentic programming systems often display inefficient processes, leading to unnecessarily prolonged trajectories.

Domain-specific question answering (QA) systems for services face unique challenges in integrating heterogeneous knowledge sources while ensuring both accuracy and safety. Existing large language models often struggle with factual consistency and context alignment in sensitive domains such as healthcare policies and government welfare. In this work, we introduce Knowledge-Aware Reasoning and Memory-Augmented Adaptation (KARMA), a novel framework designed to enhance QA performance in care scenarios. KARMA incorporates a dual-encoder architecture to fuse structured and unstructured knowledge sources, a gated memory unit to dynamically regulate external knowledge integration, and a safety-aware controllable decoder that mitigates unsafe outputs using safety classification and guided generation techniques. Extensive experiments on a proprietary QA dataset demonstrate that KARMA outperforms strong baselines in both answer quality and safety. This study offers a comprehensive solution for building trustworthy and adaptive QA systems in service contexts.

Optimizing numerical systems and mechanism design is crucial for enhancing player experience in Massively Multiplayer Online (MMO) games. Traditional optimization approaches rely on large-scale online experiments or parameter tuning over predefined statistical models, which are costly, time-consuming, and may disrupt player experience. Although simplified offline simulation systems are often adopted as alternatives, their limited fidelity prevents agents from accurately mimicking real player reasoning and reactions to interventions. To address these limitations, we propose a generative agent-based MMO simulation system empowered by Large Language Models (LLMs). By applying Supervised Fine-Tuning (SFT) and Reinforcement Learning (RL) on large-scale real player behavioral data, we adapt LLMs from general priors to game-specific domains, enabling realistic and interpretable player decision-making. In parallel, a data-driven environment model trained on real gameplay logs reconstructs dynamic in-game systems. Experiments demonstrate strong consistency with real-world player behaviors and plausible causal responses under interventions, providing a reliable, interpretable, and cost-efficient framework for data-driven numerical design optimization.