Understanding the reliability of large language models (LLMs) has recently garnered significant attention. Given LLMs' propensity to hallucinate, as well as their high sensitivity to prompt design, it is already challenging to predict the performance of an individual LLM. However, the problem becomes more complex for compound LLM systems such as cascades, where in addition to each model's standalone performance, we must understand how the error rates of different models interact. In this paper, we present a probabilistic model for the joint performance distribution of a sequence of LLMs, which enables a framework for rationally tuning the confidence thresholds of a LLM cascade using continuous optimization. Compared to selecting confidence thresholds using grid search, our parametric Markov-copula model significantly improves runtime scaling with respect to the length of the cascade and the desired resolution of the cost-error curve, turning them from intractable into low-order polynomial. In addition, the optimal thresholds computed using our continuous optimization-based algorithm increasingly outperform those found via grid search as cascade length grows, improving the area under the cost-error curve by 1.9% on average for cascades consisting of at least three models. Overall, our Markov-copula model provides a rational basis for tuning LLM cascade performance and points to the potential of probabilistic methods in analyzing LLM systems.

Russia appeared to ready itself for talks on the future of Ukraine with United States President-elect Donald Trump ahead of his swearing-in on Monday. "No special conditions are needed for this. What is required is the mutual intent and political will to have a dialogue," said Russian President Vladimir Putin's spokesman Dmitry Peskov on Saturday. But Russia expressed its parameters very quickly. Putin aide Nikolai Patrushev told Russian news outlet KP that a Ukraine settlement should be reached by the US and Russia, without Ukraine and without the European Union.

This paper presents the implementation and evaluation of a conversational agent designed for multi-party open-ended interactions. Leveraging state-of-the-art technologies such as voice direction of arrival, voice recognition, face tracking, and large language models, the system aims to facilitate natural and intuitive human-robot conversations. Deployed on the Furhat robot, the system was tested with 30 participants engaging in open-ended group conversations and then in two overlapping discussions. Quantitative metrics, such as latencies and recognition accuracy, along with qualitative measures from user questionnaires, were collected to assess performance. The results highlight the system's effectiveness in managing multi-party interactions, though improvements are needed in response relevance and latency. This study contributes valuable insights for advancing human-robot interaction, particularly in enhancing the naturalness and engagement in group conversations.

The escalating demand for long-context applications has intensified the necessity of extending the LLM context windows. Despite recent fine-tuning approaches successfully expanding context lengths, their high memory footprints, especially for activations, present a critical practical limitation. Current parameter-efficient fine-tuning methods prioritize reducing parameter update overhead over addressing activation memory constraints. Similarly, existing sparsity mechanisms improve computational efficiency but overlook activation memory optimization due to the phenomenon of Shadowy Activation. In this paper, we propose LeMo, the first LLM fine-tuning system that explores and exploits a new token-level sparsity mechanism inherent in long-context scenarios, termed Contextual Token Sparsity. LeMo minimizes redundant token involvement by assessing the informativeness of token embeddings while preserving model accuracy. Specifically, LeMo introduces three key techniques: (1) Token Elimination, dynamically identifying and excluding redundant tokens across varying inputs and layers. (2) Pattern Prediction, utilizing well-trained predictors to approximate token sparsity patterns with minimal overhead. (3) Kernel Optimization, employing permutation-free and segment-based strategies to boost system performance. We implement LeMo as an end-to-end fine-tuning system compatible with various LLM architectures and other optimization techniques. Comprehensive evaluations demonstrate that LeMo reduces memory consumption by up to 1.93x and achieves up to 1.36x speedups, outperforming state-of-the-art fine-tuning systems.

Generative artificial intelligence (GenAI) holds great promise as a tool to support personalized learning. Teachers need tools to efficiently and effectively enhance content readability of educational texts so that they are matched to individual students reading levels, while retaining key details. Large Language Models (LLMs) show potential to fill this need, but previous research notes multiple shortcomings in current approaches. In this study, we introduced a generalized approach and metrics for the systematic evaluation of the accuracy and consistency in which LLMs, prompting techniques, and a novel multi-agent architecture to simplify sixty informational reading passages, reducing each from the twelfth grade level down to the eighth, sixth, and fourth grade levels. We calculated the degree to which each LLM and prompting technique accurately achieved the targeted grade level for each passage, percentage change in word count, and consistency in maintaining keywords and key phrases (semantic similarity). One-sample t-tests and multiple regression models revealed significant differences in the best performing LLM and prompt technique for each of the four metrics. Both LLMs and prompting techniques demonstrated variable utility in grade level accuracy and consistency of keywords and key phrases when attempting to level content down to the fourth grade reading level. These results demonstrate the promise of the application of LLMs for efficient and precise automated text simplification, the shortcomings of current models and prompting methods in attaining an ideal balance across various evaluation criteria, and a generalizable method to evaluate future systems.

Recent advancements in text-to-image generation models have excelled in creating diverse and realistic images. This success extends to food imagery, where various conditional inputs like cooking styles, ingredients, and recipes are utilized. However, a yet-unexplored challenge is generating a sequence of procedural images based on cooking steps from a recipe. This could enhance the cooking experience with visual guidance and possibly lead to an intelligent cooking simulation system. To fill this gap, we introduce a novel task called \textbf{cooking procedural image generation}. This task is inherently demanding, as it strives to create photo-realistic images that align with cooking steps while preserving sequential consistency. To collectively tackle these challenges, we present \textbf{CookingDiffusion}, a novel approach that leverages Stable Diffusion and three innovative Memory Nets to model procedural prompts. These prompts encompass text prompts (representing cooking steps), image prompts (corresponding to cooking images), and multi-modal prompts (mixing cooking steps and images), ensuring the consistent generation of cooking procedural images. To validate the effectiveness of our approach, we preprocess the YouCookII dataset, establishing a new benchmark. Our experimental results demonstrate that our model excels at generating high-quality cooking procedural images with remarkable consistency across sequential cooking steps, as measured by both the FID and the proposed Average Procedure Consistency metrics. Furthermore, CookingDiffusion demonstrates the ability to manipulate ingredients and cooking methods in a recipe. We will make our code, models, and dataset publicly accessible.

Multi-modal document retrieval is designed to identify and retrieve various forms of multi-modal content, such as figures, tables, charts, and layout information from extensive documents. Despite its significance, there is a notable lack of a robust benchmark to effectively evaluate the performance of systems in multi-modal document retrieval. To address this gap, this work introduces a new benchmark, named as MMDocIR, encompassing two distinct tasks: page-level and layout-level retrieval. The former focuses on localizing the most relevant pages within a long document, while the latter targets the detection of specific layouts, offering a more fine-grained granularity than whole-page analysis. A layout can refer to a variety of elements such as textual paragraphs, equations, figures, tables, or charts. The MMDocIR benchmark comprises a rich dataset featuring expertly annotated labels for 1,685 questions and bootstrapped labels for 173,843 questions, making it a pivotal resource for advancing multi-modal document retrieval for both training and evaluation. Through rigorous experiments, we reveal that (i) visual retrievers significantly outperform their text counterparts, (ii) MMDocIR train set can effectively benefit the training process of multi-modal document retrieval and (iii) text retrievers leveraging on VLM-text perform much better than those using OCR-text. These findings underscores the potential advantages of integrating visual elements for multi-modal document retrieval.

We propose a novel cooperative multi-agent reinforcement learning (MARL) approach for networked agents. In contrast to previous methods that rely on complete state information or joint observations, our agents must learn how to reach shared objectives under partial observability. During training, they collect individual rewards and approximate a team value function through local communication, resulting in cooperative behavior. To describe our problem, we introduce the networked dynamic partially observable Markov game framework, where agents communicate over a switching topology communication network. Our distributed method, DNA-MARL, uses a consensus mechanism for local communication and gradient descent for local computation. DNA-MARL increases the range of the possible applications of networked agents, being well-suited for real world domains that impose privacy and where the messages may not reach their recipients. We evaluate DNA-MARL across benchmark MARL scenarios. Our results highlight the superior performance of DNA-MARL over previous methods.

Classifying genome sequences based on metadata has been an active area of research in comparative genomics for decades with many important applications across the life sciences. Established methods for classifying genomes can be broadly grouped into sequence alignment-based and alignment-free models. Conventional alignment-based models rely on genome similarity measures calculated based on local sequence alignments or consistent ordering among sequences. However, such methods are computationally expensive when dealing with large ensembles of even moderately sized genomes. In contrast, alignment-free (AF) approaches measure genome similarity based on summary statistics in an unsupervised setting and are efficient enough to analyze large datasets. However, both alignment-based and AF methods typically assume fixed scoring rubrics that lack the flexibility to assign varying importance to different parts of the sequences based on prior knowledge. In this study, we integrate AI and network science approaches to develop a comparative genomic analysis framework that addresses these limitations. Our approach, termed the Genome Misclassification Network Analysis (GMNA), simultaneously leverages misclassified instances, a learned scoring rubric, and label information to classify genomes based on associated metadata and better understand potential drivers of misclassification. We evaluate the utility of the GMNA using Naive Bayes and convolutional neural network models, supplemented by additional experiments with transformer-based models, to construct SARS-CoV-2 sampling location classifiers using over 500,000 viral genome sequences and study the resulting network of misclassifications. We demonstrate the global health potential of the GMNA by leveraging the SARS-CoV-2 genome misclassification networks to investigate the role human mobility played in structuring geographic clustering of SARS-CoV-2.

Introduction: Substance use disorders (SUDs) have emerged as a pressing public health crisis in the United States, with adolescent substance use often leading to SUDs in adulthood. Effective strategies are needed to prevent this progression. To help in filling this need, we develop a novel and the first-ever absolute risk prediction model for cannabis use disorder (CUD) for adolescent or young adult cannabis users. Methods: We train a Bayesian machine learning model that provides a personalized CUD absolute risk for adolescent or young adult cannabis users using data from the National Longitudinal Study of Adolescent to Adult Health. Model performance is assessed using 5-fold cross-validation (CV) with area under the curve (AUC) and ratio of the expected to observed number of cases (E/O). External validation of the final model is conducted using two independent datasets. Results: The proposed model has five risk factors: biological sex, delinquency, and scores on personality traits of conscientiousness, neuroticism, and openness. For predicting CUD risk within five years of first cannabis use, AUC and E/O, computed via 5-fold CV, were 0.68 and 0.95, respectively. For the same type of prediction in external validation, AUC values were 0.64 and 0.75, with E/O values of 0.98 and 1, indicating good discrimination and calibration performances of the model. Discussion and Conclusion: The proposed model is the first absolute risk prediction model for an SUD. It can aid clinicians in identifying adolescent/youth substance users at a high risk of developing CUD in future for clinically appropriate interventions.