Quantum Transfer Learning (QTL) recently gained popularity as a hybrid quantum-classical approach for image classification tasks by efficiently combining the feature extraction capabilities of large Convolutional Neural Networks with the potential benefits of Quantum Machine Learning (QML). Existing approaches, however, only utilize gate-based Variational Quantum Circuits for the quantum part of these procedures. In this work we present an approach to employ Quantum Annealing (QA) in QTL-based image classification. Specifically, we propose using annealing-based Quantum Boltzmann Machines as part of a hybrid quantum-classical pipeline to learn the classification of real-world, large-scale data such as medical images through supervised training. We demonstrate our approach by applying it to the three-class COVID-CT-MD dataset, a collection of lung Computed Tomography (CT) scan slices. Using Simulated Annealing as a stand-in for actual QA, we compare our method to classical transfer learning, using a neural network of the same order of magnitude, to display its improved classification performance. We find that our approach consistently outperforms its classical baseline in terms of test accuracy and AUC-ROC-Score and needs less training epochs to do this.

In this work, we study the features extracted by English self-supervised learning (SSL) models in cross-lingual contexts and propose a new metric to predict the quality of feature representations. Using automatic speech recognition (ASR) as a downstream task, we analyze the effect of model size, training objectives, and model architecture on the models' performance as a feature extractor for a set of topologically diverse corpora. We develop a novel metric, the Phonetic-Syntax Ratio (PSR), to measure the phonetic and synthetic information in the extracted representations using deep generalized canonical correlation analysis. Results show the contrastive loss in the wav2vec2.0 objective facilitates more effective cross-lingual feature extraction. There is a positive correlation between PSR scores and ASR performance, suggesting that phonetic information extracted by monolingual SSL models can be used for downstream tasks in cross-lingual settings. The proposed metric is an effective indicator of the quality of the representations and can be useful for model selection.

Function is increasingly recognized as an important indicator of whole-person health, although it receives little attention in clinical natural language processing research. We introduce the first public annotated dataset specifically on the Mobility domain of the International Classification of Functioning, Disability and Health (ICF), aiming to facilitate automatic extraction and analysis of functioning information from free-text clinical notes. We utilize the National NLP Clinical Challenges (n2c2) research dataset to construct a pool of candidate sentences using keyword expansion. Our active learning approach, using query-by-committee sampling weighted by density representativeness, selects informative sentences for human annotation. We train BERT and CRF models, and use predictions from these models to guide the selection of new sentences for subsequent annotation iterations. Our final dataset consists of 4,265 sentences with a total of 11,784 entities, including 5,511 Action entities, 5,328 Mobility entities, 306 Assistance entities, and 639 Quantification entities. The inter-annotator agreement (IAA), averaged over all entity types, is 0.72 for exact matching and 0.91 for partial matching. We also train and evaluate common BERT models and state-of-the-art Nested NER models. The best F1 scores are 0.84 for Action, 0.7 for Mobility, 0.62 for Assistance, and 0.71 for Quantification. Empirical results demonstrate promising potential of NER models to accurately extract mobility functioning information from clinical text. The public availability of our annotated dataset will facilitate further research to comprehensively capture functioning information in electronic health records (EHRs).

When a speaker verification (SV) system operates far from the sound sourced, significant challenges arise due to the interference of noise and reverberation. Studies have shown that incorporating phonetic information into speaker embedding can improve the performance of text-independent SV. Inspired by this observation, we propose a joint-training speech recognition and speaker recognition (JTSS) framework to exploit phonetic content for far-field SV. The framework encourages speaker embeddings to preserve phonetic information by matching the frame-based feature maps of a speaker embedding network with wav2vec's vectors. The intuition is that phonetic information can preserve low-level acoustic dynamics with speaker information and thus partly compensate for the degradation due to noise and reverberation. Results show that the proposed framework outperforms the standard speaker embedding on the VOiCES Challenge 2019 evaluation set and the VoxCeleb1 test set. This indicates that leveraging phonetic information under far-field conditions is effective for learning robust speaker representations.

Replicating the innate human ability to detect all objects based on free-form texts at any granularity remains a formidable challenge for Vision-Language models. Current Large Vision Language Models (LVLMs) are predominantly constrained to grounding a single, pre-existing object, relying solely on data from Referring Expression Comprehension tasks. The limitation leads to a compromise in model design, necessitating the introduction of visual expert models or the integration of customized head structures. Beyond these constraints, our research delves into the untapped potential of LVLMs and uncover their inherent capability for basic object perception, allowing them to accurately identify and locate objects of interest. Building on this insight, we introduce a novel language-prompted localization dataset designed to fully unleash the capabilities of LVLMs in integrating fine-grained object perception with precise location awareness. More importantly, we present $\textbf{Griffon}$, a purely LVLM-based baseline, which does not require the introduction of any special tokens, expert models, or additional detection modules. It simply maintains a consistent structure with popular LVLMs by unifying data formats across various localization-related scenarios and is trained end-to-end through a well-designed pipeline. Comprehensive experiments demonstrate that $\textbf{Griffon}$ not only achieves state-of-the-art performance on the fine-grained RefCOCO series but also approaches the capabilities of the expert model Faster RCNN on the detection benchmark MSCOCO.

Machine learning problems rely heavily on stochastic gradient descent (SGD) for optimization. The effectiveness of SGD is contingent upon accurately estimating gradients from a mini-batch of data samples. Instead of the commonly used uniform sampling, adaptive or importance sampling reduces noise in gradient estimation by forming mini-batches that prioritize crucial data points. Previous research has suggested that data points should be selected with probabilities proportional to their gradient norm. Nevertheless, existing algorithms have struggled to efficiently integrate importance sampling into machine learning frameworks. In this work, we make two contributions. First, we present an algorithm that can incorporate existing importance functions into our framework. Second, we propose a simplified importance function that relies solely on the loss gradient of the output layer. By leveraging our proposed gradient estimation techniques, we observe improved convergence in classification and regression tasks with minimal computational overhead. Stochastic gradient descent (SGD) combined with back-propagation and efficient gradient techniques--such as Adam [12]--has unlocked a realm of possibilities.

Large language models (LLMs) trained on huge corpora of text datasets demonstrate intriguing capabilities, achieving state-of-the-art performance on tasks they were not explicitly trained for. The precise nature of LLM capabilities is often mysterious, and different prompts can elicit different capabilities through in-context learning. We propose a framework that enables us to analyze in-context learning dynamics to understand latent concepts underlying LLMs' behavioral patterns. This provides a more nuanced understanding than success-or-failure evaluation benchmarks, but does not require observing internal activations as a mechanistic interpretation of circuits would. Inspired by the cognitive science of human randomness perception, we use random binary sequences as context and study dynamics of in-context learning by manipulating properties of context data, such as sequence length. In the latest GPT-3.5+ models, we find emergent abilities to generate seemingly random numbers and learn basic formal languages, with striking in-context learning dynamics where model outputs transition sharply from seemingly random behaviors to deterministic repetition.

Inferring biological relationships from cellular phenotypes in high-content microscopy screens provides significant opportunity and challenge in biological research. Prior results have shown that deep vision models can capture biological signal better than hand-crafted features. This work explores how self-supervised deep learning approaches scale when training larger models on larger microscopy datasets. Our results show that both CNN- and ViT-based masked autoencoders significantly outperform weakly supervised baselines. At the high-end of our scale, a ViT-L/8 trained on over 3.5-billion unique crops sampled from 93-million microscopy images achieves relative improvements as high as 28% over our best weakly supervised baseline at inferring known biological relationships curated from public databases. Relevant code and select models released with this work can be found at: https://github.com/recursionpharma/maes_microscopy.

In the era of resource-intensive foundation models, efficient adaptation in downstream tasks has become paramount. Visual Prompting (VP), inspired by prompting in Large Language Models (LLMs), has emerged as a key transfer learning method in computer vision. Aligned with the growing significance of efficiency, research in model compression has become pivotal to alleviate the computational burden in both training and deploying over-parameterized neural networks. A key goal in model compression is the development of sparse models capable of matching or surpassing the performance of their over-parameterized, dense counterparts. While prior research has explored the impact of model sparsity on transfer learning, its effects on visual prompting-based transfer remain unclear. This study addresses this gap, revealing that model sparsity adversely affects the performance of visual prompting-based transfer, particularly in low-data-volume scenarios. Furthermore, our findings highlight the negative influence of sparsity on the calibration of downstream visual-prompted models. This empirical exploration calls for a nuanced understanding beyond accuracy in sparse settings, opening avenues for further research in Visual Prompting for sparse models. Code and logs can be accessed at https://github.com/landskape-ai/Reprogram_LT .

Robust segmentation is critical for deriving quantitative measures from large-scale, multi-center, and longitudinal medical scans. Manually annotating medical scans, however, is expensive and labor-intensive and may not always be available in every domain. Unsupervised domain adaptation (UDA) is a well-studied technique that alleviates this label-scarcity problem by leveraging available labels from another domain. In this study, we introduce Masked Autoencoding and Pseudo-Labeling Segmentation (MAPSeg), a $\textbf{unified}$ UDA framework with great versatility and superior performance for heterogeneous and volumetric medical image segmentation. To the best of our knowledge, this is the first study that systematically reviews and develops a framework to tackle four different domain shifts in medical image segmentation. More importantly, MAPSeg is the first framework that can be applied to $\textbf{centralized}$, $\textbf{federated}$, and $\textbf{test-time}$ UDA while maintaining comparable performance. We compare MAPSeg with previous state-of-the-art methods on a private infant brain MRI dataset and a public cardiac CT-MRI dataset, and MAPSeg outperforms others by a large margin (10.5 Dice improvement on the private MRI dataset and 5.7 on the public CT-MRI dataset). MAPSeg poses great practical value and can be applied to real-world problems. Our code and pretrained model will be available later.