Fox News anchor Bret Baier has the latest on the Murdoch Children's Research Institute's partnership with the Gladstone Institutes for the'Decoding Broken Hearts' initiative on'Special Report.' Australia's Murdoch Children's Research Institute is helping scientists use stem cell medicine and artificial intelligence to develop precision therapies for pediatric heart disease, the leading cause of death and disability in children. Around 260,000 children die from heart disease around the world each year. In the U.S., a child is born with a heart defect every 15 minutes. "We're really interested in understanding how kids develop heart disease and where we can interfere to stop it progressing," Murdoch Children's Research Institute (MCRI) Heart Disease Group Leader David Elliott said.

In this paper, we introduce Rank-R1, a novel LLM-based reranker that performs reasoning over both the user query and candidate documents before performing the ranking task. Existing document reranking methods based on large language models (LLMs) typically rely on prompting or fine-tuning LLMs to order or label candidate documents according to their relevance to a query. For Rank-R1, we use a reinforcement learning algorithm along with only a small set of relevance labels (without any reasoning supervision) to enhance the reasoning ability of LLM-based rerankers. Our hypothesis is that adding reasoning capabilities to the rerankers can improve their relevance assessement and ranking capabilities. Our experiments on the TREC DL and BRIGHT datasets show that Rank-R1 is highly effective, especially for complex queries. In particular, we find that Rank-R1 achieves effectiveness on in-domain datasets at par with that of supervised fine-tuning methods, but utilizing only 18\% of the training data used by the fine-tuning methods. We also find that the model largely outperforms zero-shot and supervised fine-tuning when applied to out-of-domain datasets featuring complex queries, especially when a 14B-size model is used. Finally, we qualitatively observe that Rank-R1's reasoning process improves the explainability of the ranking results, opening new opportunities for search engine results presentation and fruition.

Large Language Models (LLMs) have become integral to daily life, especially advancing as intelligent assistants through on-device deployment on smartphones. However, existing LLM evaluation benchmarks predominantly focus on objective tasks like mathematics and coding in English, which do not necessarily reflect the practical use cases of on-device LLMs in real-world mobile scenarios, especially for Chinese users. To address these gaps, we introduce SmartBench, the first benchmark designed to evaluate the capabilities of on-device LLMs in Chinese mobile contexts. We analyze functionalities provided by representative smartphone manufacturers and divide them into five categories: text summarization, text Q\&A, information extraction, content creation, and notification management, further detailed into 20 specific tasks. For each task, we construct high-quality datasets comprising 50 to 200 question-answer pairs that reflect everyday mobile interactions, and we develop automated evaluation criteria tailored for these tasks. We conduct comprehensive evaluations of on-device LLMs and MLLMs using SmartBench and also assess their performance after quantized deployment on real smartphone NPUs. Our contributions provide a standardized framework for evaluating on-device LLMs in Chinese, promoting further development and optimization in this critical area. Code and data will be available at https://github.com/Lucky-Lance/SmartBench.

Context: A deeper understanding of human factors in software engineering (SE) is essential for improving team collaboration, decision-making, and productivity. Communication channels like code reviews and chats provide insights into developers' psychological and emotional states. While large language models excel at text analysis, they often lack transparency and precision. Psycholinguistic tools like Linguistic Inquiry and Word Count (LIWC) offer clearer, interpretable insights into cognitive and emotional processes exhibited in text. Despite its wide use in SE research, no comprehensive review of LIWC's use has been conducted. Objective: We examine the importance of psycholinguistic tools, particularly LIWC, and provide a thorough analysis of its current and potential future applications in SE research. Methods: We conducted a systematic review of six prominent databases, identifying 43 SE-related papers using LIWC. Our analysis focuses on five research questions. Results: Our findings reveal a wide range of applications, including analyzing team communication to detect developer emotions and personality, developing ML models to predict deleted Stack Overflow posts, and more recently comparing AI-generated and human-written text. LIWC has been primarily used with data from project management platforms (e.g., GitHub) and Q&A forums (e.g., Stack Overflow). Key BSE concepts include Communication, Organizational Climate, and Positive Psychology. 26 of 43 papers did not formally evaluate LIWC. Concerns were raised about some limitations, including difficulty handling SE-specific vocabulary. Conclusion: We highlight the potential of psycholinguistic tools and their limitations, and present new use cases for advancing the research of human factors in SE (e.g., bias in human-LLM conversations).

The rise of generative chat-based Large Language Models (LLMs) over the past two years has spurred a race to develop systems that promise near-human conversational and reasoning experiences. However, recent studies indicate that the language understanding offered by these models remains limited and far from human-like performance, particularly in grasping the contextual meanings of words, an essential aspect of reasoning. In this paper, we present a simple yet computationally efficient framework for multilingual Word Sense Disambiguation (WSD). Our approach reframes the WSD task as a cluster discrimination analysis over a semantic network refined from BabelNet using group algebra. We validate our methodology across multiple WSD benchmarks, achieving a new state of the art for all languages and tasks, as well as in individual assessments by part of speech. Notably, our model significantly surpasses the performance of current alternatives, even in low-resource languages, while reducing the parameter count by 72%.

Finetuning provides a scalable and cost-effective means of customizing language models for specific tasks or response styles, with greater reliability than prompting or in-context learning. In contrast, the conventional wisdom is that injecting knowledge via finetuning results in brittle performance and poor generalization. We argue that the dichotomy of "task customization" (e.g., instruction tuning) and "knowledge injection" (e.g., teaching new facts) is a distinction without a difference. We instead identify concrete factors that explain the heterogeneous effectiveness observed with finetuning. To this end, we conduct a large-scale experimental study of finetuning the frontier Gemini v1.5 model family on a spectrum of datasets that are artificially engineered to interpolate between the strengths and failure modes of finetuning. Our findings indicate that question-answer training data formats provide much stronger knowledge generalization than document/article-style training data, numerical information can be harder for finetuning to retain than categorical information, and models struggle to apply finetuned knowledge during multi-step reasoning even when trained on similar examples -- all factors that render "knowledge injection" to be especially difficult, even after controlling for considerations like data augmentation and information volume. On the other hand, our findings also indicate that it is not fundamentally more difficult to finetune information about a real-world event than information about what a model's writing style should be.

Blind and Low Vision (BLV) people have adopted AI-powered visual interpretation applications to address their daily needs. While these applications have been helpful, prior work has found that users remain unsatisfied by their frequent errors. Recently, multimodal large language models (MLLMs) have been integrated into visual interpretation applications, and they show promise for more descriptive visual interpretations. However, it is still unknown how this advancement has changed people's use of these applications. To address this gap, we conducted a two-week diary study in which 20 BLV people used an MLLM-enabled visual interpretation application we developed, and we collected 553 entries. In this paper, we report a preliminary analysis of 60 diary entries from 6 participants. We found that participants considered the application's visual interpretations trustworthy (mean 3.75 out of 5) and satisfying (mean 4.15 out of 5). Moreover, participants trusted our application in high-stakes scenarios, such as receiving medical dosage advice. We discuss our plan to complete our analysis to inform the design of future MLLM-enabled visual interpretation systems.

Benchmarks are essential for consistent evaluation and reproducibility. The integration of Artificial Intelligence into Software Engineering (AI4SE) has given rise to numerous benchmarks for tasks such as code generation and bug fixing. However, this surge presents challenges: (1) scattered benchmark knowledge across tasks, (2) difficulty in selecting relevant benchmarks, (3) the absence of a uniform standard for benchmark development, and (4) limitations of existing benchmarks. In this paper, we review 173 studies and identify 204 AI4SE benchmarks. We classify these benchmarks, analyze their limitations, and expose gaps in practices. Based on our review, we created BenchScout, a semantic search tool to find relevant benchmarks, using automated clustering of the contexts from associated studies. We conducted a user study with 22 participants to evaluate BenchScout's usability, effectiveness, and intuitiveness which resulted in average scores of 4.5, 4.0, and 4.1 out of 5. To advance benchmarking standards, we propose BenchFrame, a unified method to enhance benchmark quality. As a case study, we applied BenchFrame to the HumanEval benchmark and addressed its main limitations. This led to HumanEvalNext, featuring (1) corrected errors, (2) improved language conversion, (3) expanded test coverage, and (4) increased difficulty. We then evaluated ten state-of-the-art code language models on HumanEval, HumanEvalPlus, and HumanEvalNext. On HumanEvalNext, models showed a pass@1 score reduction of 31.22% and 19.94% compared to HumanEval and HumanEvalPlus, respectively.

Real-world household tasks present significant challenges for mobile manipulation robots. An analysis of existing robotics benchmarks reveals that successful task performance hinges on three key whole-body control capabilities: bimanual coordination, stable and precise navigation, and extensive end-effector reachability. Achieving these capabilities requires careful hardware design, but the resulting system complexity further complicates visuomotor policy learning. To address these challenges, we introduce the BEHAVIOR Robot Suite (BRS), a comprehensive framework for whole-body manipulation in diverse household tasks. Built on a bimanual, wheeled robot with a 4-DoF torso, BRS integrates a cost-effective whole-body teleoperation interface for data collection and a novel algorithm for learning whole-body visuomotor policies. We evaluate BRS on five challenging household tasks that not only emphasize the three core capabilities but also introduce additional complexities, such as long-range navigation, interaction with articulated and deformable objects, and manipulation in confined spaces. We believe that BRS's integrated robotic embodiment, data collection interface, and learning framework mark a significant step toward enabling real-world whole-body manipulation for everyday household tasks. BRS is open-sourced at https://behavior-robot-suite.github.io/

Rapid advances in AI are beginning to reshape national security. Destabilizing AI developments could rupture the balance of power and raise the odds of great-power conflict, while widespread proliferation of capable AI hackers and virologists would lower barriers for rogue actors to cause catastrophe. Superintelligence -- AI vastly better than humans at nearly all cognitive tasks -- is now anticipated by AI researchers. Just as nations once developed nuclear strategies to secure their survival, we now need a coherent superintelligence strategy to navigate a new period of transformative change. We introduce the concept of Mutual Assured AI Malfunction (MAIM): a deterrence regime resembling nuclear mutual assured destruction (MAD) where any state's aggressive bid for unilateral AI dominance is met with preventive sabotage by rivals. Given the relative ease of sabotaging a destabilizing AI project -- through interventions ranging from covert cyberattacks to potential kinetic strikes on datacenters -- MAIM already describes the strategic picture AI superpowers find themselves in. Alongside this, states can increase their competitiveness by bolstering their economies and militaries through AI, and they can engage in nonproliferation to rogue actors to keep weaponizable AI capabilities out of their hands. Taken together, the three-part framework of deterrence, nonproliferation, and competitiveness outlines a robust strategy to superintelligence in the years ahead.