In many real-world tasks, the concerned objects can be represented as a multi-instance bag associated with a candidate label set, which consists of one ground-truth label and several false positive labels.

Magnetic Resonance Fingerprinting (MRF) enables fast quantitative imaging by matching signal evolutions to a predefined dictionary. However, conventional dictionary matching suffers from exponential growth in computational cost and memory usage as the number of parameters increases, limiting its scalability to multi-parametric mapping. To address this, recent work has explored deep learning-based approaches as alternatives to DM. We propose GAST-Mamba, an end-to-end framework that combines a dual Mamba-based encoder with a Gate-Aware Spatial-Temporal (GAST) processor. Built on structured state-space models, our architecture efficiently captures long-range spatial dependencies with linear complexity. On 5 times accelerated simulated MRF data (200 frames), GAST-Mamba achieved a T1 PSNR of 33.12~dB, outperforming SCQ (31.69~dB). For T2 mapping, it reached a PSNR of 30.62~dB and SSIM of 0.9124. In vivo experiments further demonstrated improved anatomical detail and reduced artifacts. Ablation studies confirmed that each component contributes to performance, with the GAST module being particularly important under strong undersampling. These results demonstrate the effectiveness of GAST-Mamba for accurate and robust reconstruction from highly undersampled MRF acquisitions, offering a scalable alternative to traditional DM-based methods.

Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions worldwide. In the absence of effective treatment options, early diagnosis is crucial for initiating management strategies to delay disease onset and slow down its progression. In this study, we propose Retformer, a novel transformer-based architecture for detecting AD using retinal imaging modalities, leveraging the power of transformers and explainable artificial intelligence. The Retformer model is trained on datasets of different modalities of retinal images from patients with AD and age-matched healthy controls, enabling it to learn complex patterns and relationships between image features and disease diagnosis. To provide insights into the decision-making process of our model, we employ the Gradient-weighted Class Activation Mapping algorithm to visualize the feature importance maps, highlighting the regions of the retinal images that contribute most significantly to the classification outcome. These findings are compared to existing clinical studies on detecting AD using retinal biomarkers, allowing us to identify the most important features for AD detection in each imaging modality. The Retformer model outperforms a variety of benchmark algorithms across different performance metrics by margins of up to 11\.

--Soil organic carbon (SOC) is a critical indicator of soil health, but its accurate estimation from satellite imagery is hindered in vegetated regions due to spectral contamination from plant cover, which obscures soil reflectance and reduces model reliability. This study proposes the Reflectance Transformation Generative Adversarial Network (ReflectGAN), a novel paired GAN-based framework designed to reconstruct accurate bare soil reflectance from vegetated soil satellite observations. Using the LUCAS 2018 dataset and corresponding Landsat 8 imagery, we trained multiple learning-based models on both original and ReflectGAN-reconstructed reflectance inputs. Models trained on ReflectGAN outputs consistently outperformed those using existing vegetation correction methods. The performance of the models with ReflectGAN is also better compared to their counterparts when applied to another dataset, i.e., Sentinel-2 imagery. These findings demonstrate the potential of ReflectGAN to improve SOC estimation accuracy in vegetated landscapes, supporting more reliable soil monitoring. OIL organic carbon (SOC) is a fundamental indicator of soil health, influencing agricultural productivity, carbon sequestration, improved soil moisture retention and overall ecosystem sustainability. Accurate estimation of SOC is essential for promoting sustainable agriculture, improving soil management practices, and monitoring environmental changes [1], [2]. Traditional methods for estimating SOC rely on laboratory-based soil analyses, which, although precise, are labor-intensive, costly, and limited in spatial coverage [3], [4]. D. Datta and M. Paul are with the School of Computing, Mathematics, and Engineering, Charles Sturt University, Bathurst, NSW 2795, Australia, and also with the Cooperative Research Centre for High Performance Soils, Callaghan, NSW 2308, Australia (e-mail: ddatta@csu.edu.au; M. Murshed is with the School of Information Technology, Deakin University, Burwood, VIC 3125, Australia (e-mail: manzur.murshed@deakin.edu.au). S. W . Teng is with the Institute of Innovation, Science and Sustainability, Federation University, Mount Helen, VIC 3350, Australia, and also with the Cooperative Research Centre for High Performance Soils, Callaghan, NSW 2308, Australia (e-mail: s.w.teng@federation.edu.au). Laboratory-based hyperspectral imaging (HSI) provides a powerful tool for SOC estimation by offering high spatial and spectral resolution, enabling detailed analysis of soil properties without the need for destructive sampling [5]-[7]. Numerous studies have validated the effectiveness of HSI in accurately estimating SOC levels [7], [8]. However, the widespread deployment of HSI is constrained by the high cost of equipment and limited accessibility, making it impractical for large-scale applications.

Multi-instance partial-label learning (MIPL) is an emerging learning framework where each training sample is represented as a multi-instance bag associated with a candidate label set. Existing MIPL algorithms often overlook the margins for attention scores and predicted probabilities, leading to suboptimal generalization performance. A critical issue with these algorithms is that the highest prediction probability of the classifier may appear on a non-candidate label. In this paper, we propose an algorithm named MIPLMA, i.e., Multi-Instance Partial-Label learning with Margin Adjustment, which adjusts the margins for attention scores and predicted probabilities. We introduce a margin-aware attention mechanism to dynamically adjust the margins for attention scores and propose a margin distribution loss to constrain the margins between the predicted probabilities on candidate and non-candidate label sets. Experimental results demonstrate the superior performance of MIPLMA over existing MIPL algorithms, as well as other well-established multi-instance learning algorithms and partial-label learning algorithms.

Producing optimized and accurate transmission spectra of exoplanets from telescope data has traditionally been a manual and labor-intensive procedure. Here we present the results of the first attempt to improve and standardize this procedure using artificial intelligence (AI) based processing of light curves and spectroscopic data from transiting exoplanets observed with the Hubble Space Telescope's (HST) Wide Field Camera 3 (WFC3) instrument. We implement an AI-based parameter optimizer that autonomously operates the Eureka pipeline to produce homogeneous transmission spectra of publicly available HST WFC3 datasets, spanning exoplanet types from hot Jupiters to sub-Neptunes. Surveying 42 exoplanets with temperatures between 280 and 2580 Kelvin, we confirm modeled relationships between the amplitude of the water band at 1.4um in hot Jupiters and their equilibrium temperatures. We also identify a similar, novel trend in Neptune/sub-Neptune atmospheres, but shifted to cooler temperatures. Excitingly, a planet mass versus equilibrium temperature diagram reveals a "Clear Sky Corridor," where planets between 700 and 1700 Kelvin (depending on the mass) show stronger 1.4um H2O band measurements. This novel trend points to metallicity as a potentially important driver of aerosol formation. As we unveil and include these new discoveries into our understanding of aerosol formation, we enter a thrilling future for the study of exoplanet atmospheres. With HST sculpting this foundational understanding for aerosol formation in various exoplanet types, ranging from Jupiters to sub-Neptunes, we present a compelling platform for the James Webb Space Telescope (JWST) to discover similar atmospheric trends for more planets across a broader wavelength range.

Latent confounders are a fundamental challenge for inferring causal effects from observational data. The instrumental variable (IV) approach is a practical way to address this challenge. Existing IV based estimators need a known IV or other strong assumptions, such as the existence of two or more IVs in the system, which limits the application of the IV approach. In this paper, we consider a relaxed requirement, which assumes there is an IV proxy in the system without knowing which variable is the proxy. We propose a Variational AutoEncoder (VAE) based disentangled representation learning method to learn an IV representation from a dataset with latent confounders and then utilise the IV representation to obtain an unbiased estimation of the causal effect from the data. Extensive experiments on synthetic and real-world data have demonstrated that the proposed algorithm outperforms the existing IV based estimators and VAE-based estimators.

To obtain better value estimation in reinforcement learning, we propose a novel algorithm based on the double actor-critic framework with temporal difference error-driven regularization, abbreviated as TDDR. TDDR employs double actors, with each actor paired with a critic, thereby fully leveraging the advantages of double critics. Additionally, TDDR introduces an innovative critic regularization architecture. Compared to classical deterministic policy gradient-based algorithms that lack a double actor-critic structure, TDDR provides superior estimation. Moreover, unlike existing algorithms with double actor-critic frameworks, TDDR does not introduce any additional hyperparameters, significantly simplifying the design and implementation process. Experiments demonstrate that TDDR exhibits strong competitiveness compared to benchmark algorithms in challenging continuous control tasks.