We present a novel approach for explaining Gaussian processes (GPs) that can utilize the full analytical covariance structure present in GPs.

From the original abstract: This thesis initially aims to study the pain assessment process from a clinical-theoretical perspective while exploring and examining existing automatic approaches. Building on this foundation, the primary objective of this Ph.D. project is to develop innovative computational methods for automatic pain assessment that achieve high performance and are applicable in real clinical settings. A primary goal is to thoroughly investigate and assess significant factors, including demographic elements that impact pain perception, as recognized in pain research, through a computational standpoint. Within the limits of the available data in this research area, our goal was to design, develop, propose, and offer automatic pain assessment pipelines for unimodal and multimodal configurations that are applicable to the specific requirements of different scenarios. The studies published in this Ph.D. thesis showcased the effectiveness of the proposed methods, achieving state-of-the-art results. Additionally, they paved the way for exploring new approaches in artificial intelligence, foundation models, and generative artificial intelligence.

Visual speech recognition (VSR), which decodes spoken words from video data, offers significant benefits, particularly when audio is unavailable. However, the high dimensionality of video data leads to prohibitive computational costs that demand powerful hardware, limiting VSR deployment on resource-constrained devices. This work addresses this limitation by developing lightweight VSR architectures. Leveraging efficient operation design paradigms, we create compact yet powerful models with reduced resource requirements and minimal accuracy loss. We train and evaluate our models on a large-scale public dataset for recognition of words from video sequences, demonstrating their effectiveness for practical applications. We also conduct an extensive array of ablative experiments to thoroughly analyze the size and complexity of each model. Code and trained models will be made publicly available.

Natural Language Processing (NLP) for lesser-resourced languages faces persistent challenges, including limited datasets, inherited biases from high-resource languages, and the need for domain-specific solutions. This study addresses these gaps for Modern Greek through three key contributions. First, we evaluate the performance of open-source (Llama-70b) and closed-source (GPT-4o mini) large language models (LLMs) on seven core NLP tasks with dataset availability, revealing task-specific strengths, weaknesses, and parity in their performance. Second, we expand the scope of Greek NLP by reframing Authorship Attribution as a tool to assess potential data usage by LLMs in pre-training, with high 0-shot accuracy suggesting ethical implications for data provenance. Third, we showcase a legal NLP case study, where a Summarize, Translate, and Embed (STE) methodology outperforms the traditional TF-IDF approach for clustering \emph{long} legal texts. Together, these contributions provide a roadmap to advance NLP in lesser-resourced languages, bridging gaps in model evaluation, task innovation, and real-world impact.

Unimodality constitutes a key property indicating grouping behavior of the data around a single mode of its density. We propose a method that partitions univariate data into unimodal subsets through recursive splitting around valley points of the data density. For valley point detection, we introduce properties of critical points on the convex hull of the empirical cumulative density function (ecdf) plot that provide indications on the existence of density valleys. Next, we apply a unimodal data modeling approach that provides a statistical model for each obtained unimodal subset in the form of a Uniform Mixture Model (UMM). Consequently, a hierarchical statistical model of the initial dataset is obtained in the form of a mixture of UMMs, named as the Unimodal Mixture Model (UDMM). The proposed method is non-parametric, hyperparameter-free, automatically estimates the number of unimodal subsets and provides accurate statistical models as indicated by experimental results on clustering and density estimation tasks.

Path-based explanations provide intrinsic insights into graph-based recommendation models. However, most previous work has focused on explaining an individual recommendation of an item to a user. In this paper, we propose summary explanations, i.e., explanations that highlight why a user or a group of users receive a set of item recommendations and why an item, or a group of items, is recommended to a set of users as an effective means to provide insights into the collective behavior of the recommender. We also present a novel method to summarize explanations using efficient graph algorithms, specifically the Steiner Tree and the Prize-Collecting Steiner Tree. Our approach reduces the size and complexity of summary explanations while preserving essential information, making explanations more comprehensible for users and more useful to model developers. Evaluations across multiple metrics demonstrate that our summaries outperform baseline explanation methods in most scenarios, in a variety of quality aspects.

This paper introduces the first graph-based framework for generating group counterfactual explanations to audit model fairness, a crucial aspect of trustworthy machine learning. Counterfactual explanations are instrumental in understanding and mitigating unfairness by revealing how inputs should change to achieve a desired outcome. Our framework, named Feasible Group Counterfactual Explanations (FGCEs), captures real-world feasibility constraints and constructs subgroups with similar counterfactuals, setting it apart from existing methods. It also addresses key trade-offs in counterfactual generation, including the balance between the number of counterfactuals, their associated costs, and the breadth of coverage achieved. To evaluate these trade-offs and assess fairness, we propose measures tailored to group counterfactual generation. Our experimental results on benchmark datasets demonstrate the effectiveness of our approach in managing feasibility constraints and trade-offs, as well as the potential of our proposed metrics in identifying and quantifying fairness issues.

The spread of misinformation online, most commonly known as fake news, is an important issue that has become more pronounced in the last two decades due to the prevalence of social media. Platforms like Twitter, Reddit, and Facebook, have been commonly identified as the main channels for propagating misinformation and have been criticized for not acting on addressing the conditions that permit the circulation and amplification of false information [32]. Such misinformation includes false claims and non fact-checked news items, that originate from sources of questionable credibility [113]. The problem of misinformation becomes critical when it pertains to healthcare and health issues, since it puts lives and the public health at risk. One of the first cases of widely spread misinformation in the medical domain is the falsehood that the MMR vaccine (Measles, Mumps, Rubella) causes autism [109]. The falsehood originated from a fraudulent article titled "Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children" published in the prestigious Lancet journal in 1998 [171, 197]. This study turned tens of thousands of parents against the vaccine, and as a result, in 2020, many countries, including the United Kingdom, Greece, Venezuela, and Brazil, lost their measles elimination status. In 2020, twenty-two years after publishing this study Lancet retracted the paper [203].

Large language models (LLMs) are increasingly used in medical fields. In mental health support, the early identification of linguistic markers associated with mental health conditions can provide valuable support to mental health professionals, and reduce long waiting times for patients. Despite the benefits of LLMs for mental health support, there is limited research on their application in mental health systems for languages other than English. Our study addresses this gap by focusing on the detection of depression severity in Greek through user-generated posts which are automatically translated from English. Our results show that GPT3.5-turbo is not very successful in identifying the severity of depression in English, and it has a varying performance in Greek as well. Our study underscores the necessity for further research, especially in languages with less resources. Also, careful implementation is necessary to ensure that LLMs are used effectively in mental health platforms, and human supervision remains crucial to avoid misdiagnosis.