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It is unclear whether distributed errors alone are sufficient for synapses to make coordinated updates to learn complex, nonlinear reward-based learning tasks.

Then we propose a platform, coined Geom3D, which enables benchmarking the effectiveness of geometric strategies.

However, these methods have notable limitations.

Protein-ligand binding prediction is a fundamental problem in AI-driven drug discovery.

Enzymes, as catalysts of biological systems, are the workhorses of various biological functions [35, 52, 13] (Figure 1a).

It isn't always easy to detect cheating in chess Just three judiciously deployed cheats can turn an otherwise equal chess game into a near-certain victory, a new analysis shows - and systems designed to crack down on cheating might not notice the foul play. Daniel Keren at the University of Haifa in Israel simulated 100,000 matches using the powerful Stockfish chess engine - a computer system that, at its maximum power, is better at playing chess than any human world champion. The matches were played between two computer engines competing at the level of an average chess player - 1500 on the Elo rating scale typically used to calculate skill level in chess. Half the games were logged without any further intervention, while the other half allowed occasional intervention by a stronger computer chess "player" with an Elo score of 3190 - a higher rating than any human player has ever achieved. Competitors usually have a slim advantage when playing white, with a 51 per cent chance of winning, on average, tied to the fact that they make the game's first move.

Authors pictured in order of their interview publication date (left to right, top to bottom). Each year, a small group of PhD students are chosen to participate in the AAAI/SIGAI Doctoral Consortium . This initiative provides an opportunity for the students to discuss and explore their research interests and career objectives in an interdisciplinary workshop together with a panel of established researchers. During 2025, we met with some of the students to find out more about their research and the doctoral consortium experience. Kunpeng Xu completed his PhD at the Université de Sherbrooke and is now a postdoctoral fellow at McGill University.