Myofascial pain (MP) is a leading cause of chronic low back pain, yet its tissue-level drivers remain poorly defined and lack reliable image biomarkers. Existing studies focus predominantly on muscle while neglecting fascia, fat, and other soft tissues that play integral biomechanical roles. We developed an anatomically grounded explainable artificial intelligence (AI) framework, LAYER (Layer-wise Analysis for Yielding Explainable Relevance Tissue), that analyses six tissue layers in three-dimensional (3D) ultrasound and quantifies their contribution to MP prediction. By utilizing the largest multi-model 3D ultrasound cohort consisting of over 4,000 scans, LAYER reveals that non-muscle tissues contribute substantially to pain prediction. In B-mode imaging, the deep fascial membrane (DFM) showed the highest saliency (0.420), while in combined B-mode and shear-wave images, the collective saliency of non-muscle layers (0.316) nearly matches that of muscle (0.317), challenging the conventional muscle-centric paradigm in MP research and potentially affecting the therapy methods. LAYER establishes a quantitative, interpretable framework for linking layer-specific anatomy to pain physiology, uncovering new tissue targets and providing a generalizable approach for explainable analysis of soft-tissue imaging.

Involving collaborative information in Large Language Models (LLMs) is a promising technique for adapting LLMs for recommendation. Existing methods achieve this by concatenating collaborative features with text tokens into a unified sequence input and then fine-tuning to align these features with LLM's input space. Although effective, in this work, we identify two limitations when adapting LLMs to recommendation tasks, which hinder the integration of general knowledge and collaborative information, resulting in sub-optimal recommendation performance. (1) Fine-tuning LLM with recommendation data can undermine its inherent world knowledge and fundamental competencies, which are crucial for interpreting and inferring recommendation text. (2) Incorporating collaborative features into textual prompts disrupts the semantics of the original prompts, preventing LLM from generating appropriate outputs. In this paper, we propose a new paradigm, CoRA (an acronym for Collaborative LoRA), with a collaborative weights generator. Rather than input space alignment, this method aligns collaborative information with LLM's parameter space, representing them as incremental weights to update LLM's output. This way, LLM perceives collaborative information without altering its general knowledge and text inference capabilities. Specifically, we employ a collaborative filtering model to extract user and item embeddings, converting them into collaborative weights with low-rank properties through the collaborative weights generator. We then merge the collaborative weights into LLM's weights, enabling LLM to perceive the collaborative signals and generate personalized recommendations without fine-tuning or extra collaborative tokens in prompts. Extensive experiments confirm that CoRA effectively integrates collaborative information into LLM, enhancing recommendation performance.

Good weight initialization serves as an effective measure to reduce the training cost of a deep neural network (DNN) model. The choice of how to initialize parameters is challenging and may require manual tuning, which can be time-consuming and prone to human error. To overcome such limitations, this work takes a novel step towards building a weight generator to synthesize the neural weights for initialization. We use the image-to-image translation task with generative adversarial networks (GANs) as an example due to the ease of collecting model weights spanning a wide range. Specifically, we first collect a dataset with various image editing concepts and their corresponding trained weights, which are later used for the training of the weight generator. To address the different characteristics among layers and the substantial number of weights to be predicted, we divide the weights into equal-sized blocks and assign each block an index. Subsequently, a diffusion model is trained with such a dataset using both text conditions of the concept and the block indexes. By initializing the image translation model with the denoised weights predicted by our diffusion model, the training requires only 43.3 seconds. Compared to training from scratch (i.e., Pix2pix), we achieve a 15x training time acceleration for a new concept while obtaining even better image generation quality.

In a multi-agent environment, In order to overcome and alleviate the non-stationarity of the multi-agent environment, the mainstream method is to adopt the framework of Centralized Training Decentralized Execution (CTDE). This thesis is based on the framework of CTDE, and studies the cooperative decision-making of multi-agent based on the Multi-Agent Proximal Policy Optimization (MAPPO) algorithm for multi-agent proximal policy optimization. In order to alleviate the non-stationarity of the multi-agent environment, a multi-agent communication mechanism based on weight scheduling and attention module is introduced. Different agents can alleviate the non-stationarity caused by local observations through information exchange between agents, assisting in the collaborative decision-making of agents. The specific method is to introduce a communication module in the policy network part. The communication module is composed of a weight generator, a weight scheduler, a message encoder, a message pool and an attention module. Among them, the weight generator and weight scheduler will generate weights as the selection basis for communication, the message encoder is used to compress and encode communication information, the message pool is used to store communication messages, and the attention module realizes the interactive processing of the agent's own information and communication information. This thesis proposes a Multi-Agent Communication and Global Information Optimization Proximal Policy Optimization(MCGOPPO)algorithm, and conducted experiments in the SMAC and the MPE. The experimental results show that the improvement has achieved certain effects, which can better alleviate the non-stationarity of the multi-agent environment, and improve the collaborative decision-making ability among the agents.

This work explores the large-scale multi-agent communication mechanism under a multi-agent reinforcement learning (MARL) setting. We summarize the general categories of topology for communication structures in MARL literature, which are often manually specified. Then we propose a novel framework termed as Learning Structured Communication (LSC) by using a more flexible and efficient communication topology. Our framework allows for adaptive agent grouping to form different hierarchical formations over episodes, which is generated by an auxiliary task combined with a hierarchical routing protocol. Given each formed topology, a hierarchical graph neural network is learned to enable effective message information generation and propagation among inter- and intra-group communications. In contrast to existing communication mechanisms, our method has an explicit while learnable design for hierarchical communication. Experiments on challenging tasks show the proposed LSC enjoys high communication efficiency, scalability, and global cooperation capability.

Many real-world reinforcement learning tasks require multiple agents to make sequential decisions under the agents' interaction, where well-coordinated actions among the agents are crucial to achieve the target goal better at these tasks. One way to accelerate the coordination effect is to enable multiple agents to communicate with each other in a distributed manner and behave as a group. In this paper, we study a practical scenario when (i) the communication bandwidth is limited and (ii) the agents share the communication medium so that only a restricted number of agents are able to simultaneously use the medium, as in the state-of-the-art wireless networking standards. This calls for a certain form of communication scheduling. In that regard, we propose a multi-agent deep reinforcement learning framework, called SchedNet, in which agents learn how to schedule themselves, how to encode the messages, and how to select actions based on received messages. SchedNet is capable of deciding which agents should be entitled to broadcasting their (encoded) messages, by learning the importance of each agent's partially observed information. We evaluate SchedNet against multiple baselines under two different applications, namely, cooperative communication and navigation, and predator-prey. Our experiments show a non-negligible performance gap between SchedNet and other mechanisms such as the ones without communication and with vanilla scheduling methods, e.g., round robin, ranging from 32% to 43%.

Deep neural networks have recently achieved competitive accuracy for human activity recognition. However, there is room for improvement, especially in modeling long-term temporal importance and determining the activity relevance of different temporal segments in a video. To address this problem, we propose a learnable and differentiable module: Deep Adaptive Temporal Pooling (DATP). DATP applies a self-attention mechanism to adaptively pool the classification scores of different video segments. Specifically, using frame-level features, DATP regresses importance of different temporal segments and generates weights for them. Remarkably, DATP is trained using only the video-level label. There is no need of additional supervision except video-level activity class label. We conduct extensive experiments to investigate various input features and different weight models. Experimental results show that DATP can learn to assign large weights to key video segments. More importantly, DATP can improve training of frame-level feature extractor. This is because relevant temporal segments are assigned large weights during back-propagation. Overall, we achieve state-of-the-art performance on UCF101, HMDB51 and Kinetics datasets.