The modeling of samples of distributions is a major challenge since distributions do not form a vector space. While various approaches exist for univariate distributions, including transformations to a Hilbert space, far less is known about the multivariate case. We utilize a transformation approach to map multivariate distributions to a Hilbert space via a Wasserstein slicing method that is invertible. This approach combines functional data analysis tools, such as functional principal component analysis and modes of variation, with the facility to map back to interpretable distributions. We also provide convergence guarantees for the Hilbert space representations under a broad class of such transforms. The method is illustrated using joint systolic and diastolic blood pressure data.

Alzheimer's disease (AD) is marked by cognitive decline along with the widespread of tau aggregates across the brain cortex. Due to the challenges of imaging pathology spreading flows \textit{in vivo}, however, quantitative analysis on the cortical pathways of tau propagation and its interaction with the cascade of amyloid-beta (A$\beta$) plaques lags behind the experimental insights of underlying pathophysiological mechanisms. To address this challenge, we present a physics-informed neural network, empowered by mean-field theory, to uncover the biologically meaningful spreading pathways of tau aggregates between two longitudinal snapshots. Following the notion of `prion-like' mechanism in AD, we first formulate the dynamics of tau propagation as a mean-field game (MFG), where the spread of tau aggregate at each location (aka.

Designing the sensing architecture for large-scale spatio-temporal systems is hard when accuracy requirements are specified but sensor models are uncertain or unavailable. Classical design treats sensor placement and estimation sequentially, requiring valid forward models for each sensing modality. This paper inverts the design flow: given an error budget, synthesize the measurement likelihood that enforces it while injecting minimal information beyond the dynamical prior. The likelihood is constructed by constrained optimization: among all posteriors satisfying a prescribed accuracy bound relative to a target, select the one minimizing Kullback-Leibler divergence from the prior. The solution is a maximum-entropy posterior in relative-entropy form, and the induced likelihood is the Radon-Nikodym derivative. The framework accommodates arbitrary discrepancies and is instantiated for Wasserstein distance, maximum mean discrepancy, $f$-divergences, moment constraints, and hybrid metrics. For each, we derive the discrete particle-level problem, analyze its convex or convex-relaxed structure, and present solvers with complexity scaling. A closed-form solution exists for the symmetric exponential-tilt case, and a distillation procedure converts nonparametric likelihood samples into parametric forms. A two-layer sensor design architecture embeds the synthesized likelihood in the recursive predict-update loop, connecting accuracy budgets to physical sensor placement, precision, and configuration. Numerical experiments comparing four metrics on unimodal and multimodal scenarios confirm the accuracy constraints are reliably enforced and reveal how metric choice determines the amount and spatial distribution of injected information.

PRW can be seen as the generalization of Max-SW since PRW with k =1 is equivalent to Max-SW. Similar to Max-SW, the optimization of PRW is solved by using projected gradient ascent. The detailed of the algorithm is given in Algorithm 4. We would like to recall that other methods of optimization have also been used to solved PRW such as Riemannian optimization [28], block coordinate descent [21]. However, in this paper, we consider the original and simplest method which is projected gradient ascent.

We mitigate the usual worst-case nature of minimax analysis by showing that our bounds are tight for any given31 hypothesis class, and, tight in any noise regime (Theorems 1 and 2).

Compared computation LA-SWtoGA-SWandNA-SW, the slightly; memory usingsliced computational LA-SWis itcoststhe Section 3A-SW.

New deep learning-based approaches further improve the quality of synthetic textures.