Traditional machine learning models struggle to generalize in microbiome studies where only metadata is available, especially in small-sample settings or across studies with heterogeneous label formats. In this work, we explore the use of large language models (LLMs) to classify microbial samples into ontology categories such as EMPO 3 and related biological labels, as well as to predict pathogen contamination risk, specifically the presence of E. Coli, using environmental metadata alone. We evaluate LLMs such as ChatGPT-4o, Claude 3.7 Sonnet, Grok-3, and LLaMA 4 in zero-shot and few-shot settings, comparing their performance against traditional models like Random Forests across multiple real-world datasets. Our results show that LLMs not only outperform baselines in ontology classification, but also demonstrate strong predictive ability for contamination risk, generalizing across sites and metadata distributions. These findings suggest that LLMs can effectively reason over sparse, heterogeneous biological metadata and offer a promising metadata-only approach for environmental microbiology and biosurveillance applications.

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In Cadwell Turnbull's sci-fi novel The Lesson, powerful aliens occupy the US Virgin Islands. Turnbull, who grew up on Saint Thomas, says he meets many people who have no idea that the Virgin Islands even exist. "When I first went to Pittsburgh for my undergrad, I would talk to people about the Virgin Islands, and a lot of people just had no idea that we were territories of the US," Turnbull says in Episode 387 of the Geek's Guide to the Galaxy podcast. "Because it's so small--the population is a couple hundred thousand people--it's easily overlooked." Turnbull first got interested in fantasy and science fiction from watching shows like Buffy the Vampire Slayer.

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Tesla is developing a long-haul, electric semi-truck that can drive itself and move in "platoons" that automatically follow a lead vehicle, and is getting closer to testing a prototype. Love exists, but they are not together. Reports swirled over the weekend that the entrepreneur, Elon Musk, and Amber called it quits, after publicizing their couple status in April. TheStreet's Action Alerts PLUS Portfolio Manager Jim Cramer looks at Thursday's trending stocks. Tesla had roughly 63,000 people cancel their order for the companies Model 3 car in the last year. Tesla's greatly anticipated Model 3 will finally start rolling out of the manufacturing plant. CEO, Elon Musk took to Twitter to make the announcement.