Years after initial tests, researchers are now racing to see if a vaccine developed in 2011 can help fight the current Bundibugyo outbreak in Congo. Fever was the first symptom to grip the crab-eating macaques in their high-containment laboratory on an island off Texas after being infected with the newly discovered Bundibugyo strain of ebola . Then came the weight loss, the rectal bleeding and nosebleeds, while scientists in space suits drew blood to see how the monkeys' immune systems struggled to fight the aggressive virus. But the three monkeys that had received a newly developed vaccine to protect against the understudied strain showed no symptoms of the disease, which eventually killed two-thirds of their unvaccinated companions. It was 2011, and virologist Thomas Geisbert's work developing the vaccine was done.

The DeceptionBench is designed as a research benchmark to systematically study deception behaviors in LLMs, fostering a deeper understanding of their decision-making processes in real-world scenarios. Our primary intent is to provide a standardized, transparent tool for the research community to evaluate and improve LLMs' ethical alignment, not to enable or encourage deceptive practices. To prevent potential misuse by malicious actors, we commit to publicly releasing all evaluation data under an open license. This transparency ensures that DeceptionBench's methodology and outcomes are subject to scrutiny, replication, and improvement by the research community, reducing the risk of hidden exploitation. By prioritizing openness, we aim to advance responsible AI development while safeguarding against misuse in harmful contexts. The field of Large Language Models (LLMs) has undergone remarkable evolution in recent years, reshaping the landscape of natural language processing.

Despite the remarkable advances of Large Language Models (LLMs) across diverse cognitive tasks, the rapid enhancement of these capabilities also introduces emergent deception behaviors that may induce severe risks in high-stakes deployments. More critically, the characterization of deception across realistic real-world scenarios remains underexplored. To bridge this gap, we establish DeceptionBench, the first benchmark that systematically evaluates how deceptive tendencies manifest across different societal domains, what their intrinsic behavioral patterns are, and how extrinsic factors affect them. Specifically, on the static count, the benchmark encompasses 150 meticulously designed scenarios in five domains, i.e., Economy, Healthcare, Education, Social Interaction, and Entertainment, with over 1,000 samples, providing sufficient empirical foundations for deception analysis. On the intrinsic dimension, we explore whether models exhibit self-interested egoistic tendencies or sycophantic behaviors that prioritize user appeasement. On the extrinsic dimension, we investigate how contextual factors modulate deceptive outputs under neutral conditions, reward-based incentivization, and coercive pressures. Moreover, we incorporate sustained multi-turn interaction loops to construct a more realistic simulation of real-world feedback dynamics. Extensive experiments across LLMs and Large Reasoning Models (LRMs) reveal critical vulnerabilities, particularly amplified deception under reinforcement dynamics, demonstrating that current models lack robust resistance to manipulative contextual cues and the urgent need for advanced safeguards against various deception behaviors.

An AI-designed universal vaccine targeting a broad range of coronaviruses passed its first clinical trial, proving safe and triggering an immune response in 39 healthy volunteers.

The work of Peter Aaby and Christine Stabell Benn has long been controversial. Until Robert F. Kennedy Jr. became US health policy chief, most vaccine scientists tended to ignore it. In 1996, Guinea-Bissau seemed like an ideal research post for budding pediatrician Lone Graff Stensballe. Her supervisor, a fellow Dane named Peter Aaby, had spent nearly two decades collecting data on 100,000 people living in the mud brick homes of the West African country's capital. Aaby and his partner, Christine Stabell Benn, believed that the years of research in the impoverished country had yielded a major discovery about vaccines--and what they described as "non-specific effects": The measles and tuberculosis vaccines, which were derived from live, weakened viruses and bacteria, they said, boosted child survival beyond protecting against those particular pathogens. But, the scientists said, shots made from deactivated whole germs, or pieces of them, such as the diphtheria-tetanus-pertussis (DTP) shot, caused more deaths--especially in little girls--than getting no vaccine at all.

From claims of an Israeli false flag to efforts to sell ivermectin, influencers and grifters are using lessons learned from Covid-19 to push their baseless conspiracy theories. Conspiracy theorists, wellness influencers, and grifters have already started promoting wild claims about the hantavirus outbreak that began aboard the MV, a cruise ship on the Atlantic. Some conspiracy theorists compared the outbreak to the Covid-19 pandemic, claiming it was another effort to control the global population, while others pushed a false narrative that the Covid-19 vaccine caused hantavirus. Many others promoted ivermectin as a treatment, using the incident as a way to sell emergency medical kits featuring the antiparasitic drug typically used as a horse dewormer. In more recent days, many of these same people spreading conspiracy theories have promoted the baseless and antisemitic claims that the entire incident is a false flag orchestrated by Israel.

Since 2023, Moderna and Korea University have been developing a new mRNA vaccine for hantavirus. The work has been promising so far, but a finished product isn't likely coming any time soon. US-based pharmaceutical company Moderna confirmed that it has been working on the development of hantavirus vaccines in collaboration with the Vaccine Innovation Center of Korea University College of Medicine (VIC-K). This comes after an outbreak of hantavirus occurred on a Dutch cruise ship that sailed from Argentina and disembarked its passengers and crew in the Canary Islands on May 10. At least three people aboard the MV died, and several cases were reported as serious.

Recent years have witnessed an increasing use of coordinated accounts on social media, operated by misinformation campaigns to influence public opinion and manipulate social outcomes. Consequently, there is an urgent need to develop an effective methodology for coordinated group detection to combat the misinformation on social media. However, the sparsity of account activities on social media limits the performance of existing deep learning based coordination detectors as they can not exploit useful prior knowledge. Instead, the detectors incorporated with prior knowledge suffer from limited expressive power and poor performance. Therefore, in this paper we propose a coordination detection framework incorporating neural temporal point process with prior knowledge such as temporal logic or pre-defined filtering functions. Specifically, when modeling the observed data from social media with neural temporal point process, we jointly learn a Gibbs distribution of group assignment based on how consistent an assignment is to (1) the account embedding space and (2) the prior knowledge.

The new paradigm of fine-tuning-as-a-service introduces a new attack surface for Large Language Models (LLMs): a few harmful data uploaded by users can easily trick the fine-tuning to produce an alignment-broken model. We conduct an empirical analysis and uncovera \textit{harmful embedding drift} phenomenon, showing a probable cause of the alignment-broken effect. Inspired by our findings, we propose Vaccine, a perturbation-aware alignment technique to mitigate the security risk of users fine-tuning. The core idea of Vaccine is to produce invariant hidden embeddings by progressively adding crafted perturbation to them in the alignment phase. This enables the embeddings to withstand harmful perturbation from un-sanitized user data in the fine-tuning phase. Our results on open source mainstream LLMs (e.g., Llama2, Opt, Vicuna) demonstrate that Vaccine can boost the robustness of alignment against harmful prompts induced embedding drift while reserving reasoning ability towards benign prompts.

Parents in north London have been told their children could be excluded from school if they are not fully vaccinated against measles amid an outbreak of the highly-contagious disease. Unvaccinated pupils identified as close contacts of people with measles could be excluded for 21 days in accordance with national guidelines, Enfield Council said in a letter to all parents in the borough in late January. At least 34 children have contracted measles in Enfield so far this year, the UK Health Security Agency (UKHSA) has said, and a number sent to hospital. A local health chief meanwhile told the BBC: We are worried because actually, this is a significantly increased number than what we're used to. Asking unvaccinated, close contacts of measles cases to stay off school is fairly standard practice when there are local outbreaks.