Organoids, specifically, are an active area of research, providing excellent models for human organs and their functions.

Large Language Models (LLMs) demonstrate potential in complex legal tasks like argument generation, yet their reliability remains a concern. Building upon pilot work assessing LLM generation of 3-ply legal arguments using human evaluation, this paper introduces an automated pipeline to evaluate LLM performance on this task, specifically focusing on faithfulness (absence of hallucination), factor utilization, and appropriate abstention. We define hallucination as the generation of factors not present in the input case materials and abstention as the model's ability to refrain from generating arguments when instructed and no factual basis exists. Our automated method employs an external LLM to extract factors from generated arguments and compares them against the ground-truth factors provided in the input case triples (current case and two precedent cases). We evaluated eight distinct LLMs on three tests of increasing difficulty: 1) generating a standard 3-ply argument, 2) generating an argument with swapped precedent roles, and 3) recognizing the impossibility of argument generation due to lack of shared factors and abstaining. Our findings indicate that while current LLMs achieve high accuracy (over 90%) in avoiding hallucination on viable argument generation tests (Tests 1 & 2), they often fail to utilize the full set of relevant factors present in the cases. Critically, on the abstention test (Test 3), most models failed to follow instructions to stop, instead generating spurious arguments despite the lack of common factors. This automated pipeline provides a scalable method for assessing these crucial LLM behaviors, highlighting the need for improvements in factor utilization and robust abstention capabilities before reliable deployment in legal settings. Link: https://lizhang-aiandlaw.github.io/An-Automated-Pipeline-for-Evaluating-LLM-Generated-3-ply-Case-Based-Legal-Arguments/

OLITICS and business are considered traditional spheres of human negotiation. The internet and modern goods/service characterised by several, possibly interrelated, means of communication have extended human negotiation attributes (say price of a product and terms of its delivery); ii) to new domains such as social networks, deliberative democracy, limited negotiation time as no agent can deliberate infinitely; e-commerce, cloud-based applications, [1], [2]. Besides, iii) absence of moderator to coordinate the negotiation, so the automatic bargaining and negotiation, being inevitable agents must reach agreement themselves [11]. in modern cyber-physical-social systems [3], have been established The negotiation has been widely addressed in diverse fields in variety of applications, like network negotiation, ranging from economy and sociology to computer science.

The risk of language models unintentionally reproducing copyrighted material from their training data has led to the development of various protective measures. In this paper, we propose model fusion as an effective solution to safeguard against copyright infringement. In particular, we introduce Copyright-Protecting Fusion (CP-Fuse), an algorithm that adaptively combines language models to minimize the reproduction of protected materials. CP-Fuse is inspired by the recently proposed Near-Access Free (NAF) framework and additionally incorporates a desirable balancing property that we demonstrate prevents the reproduction of memorized training data. Our results show that CP-Fuse significantly reduces the memorization of copyrighted content while maintaining high-quality text and code generation. Furthermore, we demonstrate how CP-Fuse can be integrated with other techniques for enhanced protection.

Nasopharyngeal carcinoma (NPC) is one of the understudied yet deadliest cancers in South East Asia. In Malaysia, the prevalence is identified mainly in Sarawak, among the ethnic of Bidayuh. NPC is often late-diagnosed because it is asymptomatic at the early stage. There are several tissue representations from the nasopharynx biopsy, such as nasopharyngeal inflammation (NPI), lymphoid hyperplasia (LHP), nasopharyngeal carcinoma (NPC) and normal tissue. This paper is our first initiative to identify the difference between NPC, NPI and normal cases. Seven whole slide images (WSIs) with gigapixel resolutions from seven different patients and two hospitals were experimented with using two test setups, consisting of a different set of images. The tissue regions are patched into smaller blocks and classified using DenseNet architecture with 21 dense layers. Two tests are carried out, each for proof of concept (Test 1) and real-test scenario (Test 2). The accuracy achieved for NPC class is 94.8% for Test 1 and 67.0% for Test 2. Keywords: Deep learning, Densenet, Whole slide image, Digital pathology, Nasopharyngeal carcinoma.

Automatic legal text classification systems have been proposed in the literature to address knowledge extraction from judgments and detect their aspects. However, most of these systems are black boxes even when their models are interpretable. This may raise concerns about their trustworthiness. Accordingly, this work contributes with a system combining Natural Language Processing (NLP) with Machine Learning (ML) to classify legal texts in an explainable manner. We analyze the features involved in the decision and the threshold bifurcation values of the decision paths of tree structures and present this information to the users in natural language. This is the first work on automatic analysis of legal texts combining NLP and ML along with Explainable Artificial Intelligence techniques to automatically make the models' decisions understandable to end users. Furthermore, legal experts have validated our solution, and this knowledge has also been incorporated into the explanation process as "expert-in-the-loop" dictionaries. Experimental results on an annotated data set in law categories by jurisdiction demonstrate that our system yields competitive classification performance, with accuracy values well above 90%, and that its automatic explanations are easily understandable even to non-expert users.

We study how well machine learning models trained on causal features generalize across domains. We consider 16 prediction tasks on tabular datasets covering applications in health, employment, education, social benefits, and politics. Each dataset comes with multiple domains, allowing us to test how well a model trained in one domain performs in another. For each prediction task, we select features that have a causal influence on the target of prediction. Our goal is to test the hypothesis that models trained on causal features generalize better across domains. Without exception, we find that predictors using all available features, regardless of causality, have better in-domain and out-of-domain accuracy than predictors using causal features. Moreover, even the absolute drop in accuracy from one domain to the other is no better for causal predictors than for models that use all features. If the goal is to generalize to new domains, practitioners might as well train the best possible model on all available features.

Recent immense breakthroughs in generative models such as in GPT4 have precipitated re-imagined ubiquitous usage of these models in all applications. One area that can benefit by improvements in artificial intelligence (AI) is healthcare. The note generation task from doctor-patient encounters, and its associated electronic medical record documentation, is one of the most arduous time-consuming tasks for physicians. It is also a natural prime potential beneficiary to advances in generative models. However with such advances, benchmarking is more critical than ever. Whether studying model weaknesses or developing new evaluation metrics, shared open datasets are an imperative part of understanding the current state-of-the-art. Unfortunately as clinic encounter conversations are not routinely recorded and are difficult to ethically share due to patient confidentiality, there are no sufficiently large clinic dialogue-note datasets to benchmark this task. Here we present the Ambient Clinical Intelligence Benchmark (ACI-BENCH) corpus, the largest dataset to date tackling the problem of AI-assisted note generation from visit dialogue. We also present the benchmark performances of several common state-of-the-art approaches.

Federated Learning (FL) is an emerging domain in the broader context of artificial intelligence research. Methodologies pertaining to FL assume distributed model training, consisting of a collection of clients and a server, with the main goal of achieving optimal global model with restrictions on data sharing due to privacy concerns. It is worth highlighting that the diverse existing literature in FL mostly assume stationary data generation processes; such an assumption is unrealistic in real-world conditions where concept drift occurs due to, for instance, seasonal or period observations, faults in sensor measurements. In this paper, we introduce a multiscale algorithmic framework which combines theoretical guarantees of \textit{FedAvg} and \textit{FedOMD} algorithms in near stationary settings with a non-stationary detection and adaptation technique to ameliorate FL generalization performance in the presence of concept drifts. We present a multi-scale algorithmic framework leading to $\Tilde{\mathcal{O}} ( \min \{ \sqrt{LT} , \Delta^{\frac{1}{3}}T^{\frac{2}{3}} + \sqrt{T} \})$ \textit{dynamic regret} for $T$ rounds with an underlying general convex loss function, where $L$ is the number of times non-stationary drifts occurred and $\Delta$ is the cumulative magnitude of drift experienced within $T$ rounds.