Breakthroughs, discoveries, and DIY tips sent every weekday. Tattoos, as anyone's concerned parents have reminded them, are notoriously permanent. But even ink needled under the surface of the skin can't withstand time's inescapable weathering. Untreated dead bodies eventually decay, and skin dotted with panels of stark-lined tigers or delicate wildflowers eventually break down to nothing more than the soil around it. A father and son team of morticians are trying to break that natural cycle using a secretive formula, preservative chemicals, and a taxidermist's eye.

Machine learning-based decision support systems are increasingly deployed in clinical settings, where probabilistic scoring functions are used to inform and prioritize patient management decisions. However, widely used scoring rules, such as accuracy and AUC-ROC, fail to adequately reflect key clinical priorities, including calibration, robustness to distributional shifts, and sensitivity to asymmetric error costs. In this work, we propose a principled yet practical evaluation framework for selecting calibrated thresholded classifiers that explicitly accounts for the uncertainty in class prevalences and domain-specific cost asymmetries often found in clinical settings. Building on the theory of proper scoring rules, particularly the Schervish representation, we derive an adjusted variant of cross-entropy (log score) that averages cost-weighted performance over clinically relevant ranges of class balance. The resulting evaluation is simple to apply, sensitive to clinical deployment conditions, and designed to prioritize models that are both calibrated and robust to real-world variations.

A new song from the hit Broadway show Hamilton has been released, but this ditty was not written Lin-Manuel Miranda – it was create by artificial intelligence. A film production student at California's Chapman University used an machine learning model capable of producing written content from simple commands. The system, named Calamity A.I, was fed 45TB of text data and then Elis Weiss, the human mastermind, entered one sentence: 'Here are the lyrics to a new song from the hit musical Hamilton: An American Musical.' The AI returned a full song of lyrics with four versus, a chorus and bridge that included the characters from the story. However, the system added a few extras to its version – Eliza gave Hamilton syphilis, which he then proclaimed Hillary Clinton as his new lover.

GENEVA - The World Health Organization expressed alarm Thursday at the lack of progress on curbing sexually transmitted diseases, while one of its experts warned of complacency as dating apps are spurring sexual activity. The U.N. health agency said in a fresh report that every day globally there were more than 1 million new cases of treatable sexually transmitted diseases (STD) or infections (STI). WHO found that there were more than 376 million new cases of chlamydia, gonorrhea, trichomoniasis and syphilis registered around the world in 2016 -- the latest year for which data is available. That is basically the same number as WHO reported in its previous study, based on data from 2012. A WHO expert on sexually transmitted infections, Teodora Wi, separately told journalists there were concerns that condom use may be declining as people have lost their fear of contracting HIV in step with the emergence of available and effective antiviral treatments.

People who use dating apps such as Tinder may be up to 27 times as likely to use drastic or unhealthy techniques to try and stay slim. Deliberately vomiting, taking laxatives and even using anabolic steroids is more common among dating app users, a study found. Researchers found'unrealistic' desires to look like celebrities on television and social media are driving people to damaging behaviour. And with an estimated 50million people around the world signed up to Tinder the scientists warned experts must better understand its damaging effects. Researchers said social media and TV shows reinforce'ideal' body images which drive men to try and become more muscly and women slimmer, which may drive them to drastic weight loss measures (Pictured: Love Island contestants Anton Danyluk and Amber Gill – the show is well-known for displaying young people with extremely honed bodies.

Syphilis might be more commonly associated with centuries past. But it's been on the rise for the past decade in England, with more cases last year than in any year since 1949. The disease was, in effect, eradicated in the UK in the mid-80s only to re-emerge around 1999. BBC Reality Check wanted to know why this ancient disease is rearing its head in England in the 21st Century. Syphilis is a bacterial infection that can be treated with antibiotics.