stainfuser
StainFuser: Controlling Diffusion for Faster Neural Style Transfer in Multi-Gigapixel Histology Images
Jewsbury, Robert, Wang, Ruoyu, Bhalerao, Abhir, Rajpoot, Nasir, Vu, Quoc Dang
Stain normalization algorithms aim to transform the color and intensity characteristics of a source multi-gigapixel histology image to match those of a target image, mitigating inconsistencies in the appearance of stains used to highlight cellular components in the images. We propose a new approach, StainFuser, which treats this problem as a style transfer task using a novel Conditional Latent Diffusion architecture, eliminating the need for handcrafted color components. With this method, we curate SPI-2M the largest stain normalization dataset to date of over 2 million histology images with neural style transfer for high-quality transformations. Trained on this data, StainFuser outperforms current state-of-the-art deep learning and handcrafted methods in terms of the quality of normalized images and in terms of downstream model performance on the CoNIC dataset.
- South America > Peru > Lima Department > Lima Province > Lima (0.04)
- Europe > United Kingdom (0.04)
- Europe > Switzerland (0.04)
- Europe > France > Hauts-de-France > Nord > Lille (0.04)
- Health & Medicine > Therapeutic Area > Oncology (0.67)
- Health & Medicine > Therapeutic Area > Immunology (0.67)