specimen
- North America > Canada > Ontario > Toronto (0.04)
- North America > Canada > Alberta (0.04)
- Europe > Denmark > North Jutland > Aalborg (0.04)
- Information Technology > Sensing and Signal Processing > Image Processing (1.00)
- Information Technology > Artificial Intelligence > Machine Learning > Neural Networks (1.00)
- Information Technology > Artificial Intelligence > Machine Learning > Performance Analysis (0.68)
- Information Technology > Artificial Intelligence > Natural Language (0.68)
Tyrannosaurus rex took 40 years to reach full size
New analysis of bone growth rings shows the'tyrant lizard king' grew very slowly. Breakthroughs, discoveries, and DIY tips sent six days a week. Based on the annual growth rings (like those on trees) within fossilized leg bones, scientists estimate that usually reach adulthood at around 25 years old. However, new research argues that their growth phase lasted significantly longer. They may have become fully grown--approximately eight tons--after 40 years.
- North America > United States > Oklahoma (0.05)
- North America > United States > New Jersey (0.05)
- North America > Canada (0.05)
9 new butterflies discovered in old museum archives
The team even extracted DNA from a tiny 100-year-old butterfly leg. Breakthroughs, discoveries, and DIY tips sent every weekday. When you think of butterflies, chances are you imagine unmistakable insects with bright, bold wings. But it turns out that individual butterfly species are sometimes shockingly difficult to tell apart. "Thanks to the genetic revolution and the collaboration of researchers and museums in various countries led by London's Natural History Museum, century-old butterflies are now speaking to us," Christophe Faynel, an entomologist at the Société entomologique Antilles Guyane, said in a statement .
- Asia > Japan (0.06)
- South America > Brazil (0.05)
- Oceania > New Zealand (0.05)
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Why did this ancient bird die with tiny rocks in its throat?
Science Dinosaurs Why did this ancient bird die with tiny rocks in its throat? The 120-million-year-old fossil may also be a choking hazard PSA. Breakthroughs, discoveries, and DIY tips sent every weekday. Fossils may reveal what type of animal died millions of years ago, but they rarely depict exactly they perished. Even rarer are the examples that clearly showcase an animal's exact cause of death.
- North America > United States > Illinois > Cook County > Chicago (0.05)
- Asia > China (0.05)
- Antarctica (0.05)
Real-Time Structural Health Monitoring with Bayesian Neural Networks: Distinguishing Aleatoric and Epistemic Uncertainty for Digital Twin Frameworks
Cho, Hanbin, Yu, Jecheon, Moon, Hyeonbin, Yoon, Jiyoung, Lee, Junhyeong, Kim, Giyoung, Park, Jinhyoung, Ryu, Seunghwa
Reliable real-time analysis of sensor data is essential for structural health monitoring (SHM) of high-value assets, yet a major challenge is to obtain spatially resolved full-field aleatoric and epistemic uncertainties for trustworthy decision-making. We present an integrated SHM framework that combines principal component analysis (PCA), a Bayesian neural network (BNN), and Hamiltonian Monte Carlo (HMC) inference, mapping sparse strain gauge measurements onto leading PCA modes to reconstruct full-field strain distributions with uncertainty quantification. The framework was validated through cyclic four-point bending tests on carbon fiber reinforced polymer (CFRP) specimens with varying crack lengths, achieving accurate strain field reconstruction (R squared value > 0.9) while simultaneously producing real-time uncertainty fields. A key contribution is that the BNN yields robust full-field strain reconstructions from noisy experimental data with crack-induced strain singularities, while also providing explicit representations of two complementary uncertainty fields. Considered jointly in full-field form, the aleatoric and epistemic uncertainty fields make it possible to diagnose at a local level, whether low-confidence regions are driven by data-inherent issues or by model-related limitations, thereby supporting reliable decision-making. Collectively, the results demonstrate that the proposed framework advances SHM toward trustworthy digital twin deployment and risk-aware structural diagnostics.
- Asia > South Korea > Daejeon > Daejeon (0.04)
- Asia > South Korea > Daegu > Daegu (0.04)
- Materials (1.00)
- Health & Medicine > Consumer Health (0.61)
- Energy > Renewable (0.46)
- Information Technology > Artificial Intelligence > Representation & Reasoning > Uncertainty (1.00)
- Information Technology > Artificial Intelligence > Machine Learning > Statistical Learning (1.00)
- Information Technology > Architecture > Real Time Systems (1.00)
- Information Technology > Artificial Intelligence > Machine Learning > Neural Networks > Deep Learning (0.68)
MASCOT: Analyzing Malware Evolution Through A Well-Curated Source Code Dataset
Li, Bojing, Zhong, Duo, Nadendla, Dharani, Terceros, Gabriel, Bhandar, Prajna, S, Raguvir, Nicholas, Charles
Abstract--In recent years, the explosion of malware and extensive code reuse have formed complex evolutionary connections among malware specimens. The rapid pace of development makes it challenging for existing studies to characterize recent evolutionary trends. In addition, intuitive tools to untangle these intricate connections between malware specimens or categories are urgently needed. This paper introduces a manually-reviewed malware source code dataset containing 6032 specimens. Building on and extending current research from a software engineering perspective, we systematically evaluate the scale, development costs, code quality, as well as security and dependencies of modern malware. We further introduce a multi-view genealogy analysis to clarify malware connections: at an overall view, this analysis quantifies the strength and direction of connections among specimens and categories; at a detailed view, it traces the evolutionary histories of individual specimens. Experimental results indicate that, despite persistent shortcomings in code quality, malware specimens exhibit an increasing complexity and standardization, in step with the development of mainstream software engineering practices. Meanwhile, our genealogy analysis intuitively reveals lineage expansion and evolution driven by code reuse, providing new evidence and tools for understanding the formation and evolution of the malware ecosystem. With the rapid development of information technology and large language models, malware has experienced a surge in recent years, exhibiting strong connections among categories and specimens, as well as high code reuse rates [1]. In the past 12 months, more than 107 million new malicious or potentially unwanted applications were detected [2], [3]. Many of these malware specimens are variants of previously known malware, which indicates the prevalence of code reuse and family-oriented evolution. However, the difficulty of collecting, reviewing, and labeling has resulted in a scarcity of source code datasets [4]. Existing datasets lack human curation, reliable labels, and timestamps.
- Research Report (0.64)
- Overview (0.46)
Automatic Multi-View X-Ray/CT Registration Using Bone Substructure Contours
Flepp, Roman, Nissen, Leon, Sigrist, Bastian, Nieuwland, Arend, Cavalcanti, Nicola, Fürnstahl, Philipp, Dreher, Thomas, Calvet, Lilian
Purpose: Accurate intraoperative X-ray/CT registration is essential for surgical navigation in orthopedic procedures. However, existing methods struggle with consistently achieving sub-millimeter accuracy, robustness under broad initial pose estimates or need manual key-point annotations. This work aims to address these challenges by proposing a novel multi-view X-ray/CT registration method for intraoperative bone registration. Methods: The proposed registration method consists of a multi-view, contour-based iterative closest point (ICP) optimization. Unlike previous methods, which attempt to match bone contours across the entire silhouette in both imaging modalities, we focus on matching specific subcategories of contours corresponding to bone substructures. This leads to reduced ambiguity in the ICP matches, resulting in a more robust and accurate registration solution. This approach requires only two X-ray images and operates fully automatically. Additionally, we contribute a dataset of 5 cadaveric specimens, including real X-ray images, X-ray image poses and the corresponding CT scans. Results: The proposed registration method is evaluated on real X-ray images using mean reprojection error (mRPD). The method consistently achieves sub-millimeter accuracy with a mRPD 0.67mm compared to 5.35mm by a commercial solution requiring manual intervention. Furthermore, the method offers improved practical applicability, being fully automatic. Conclusion: Our method offers a practical, accurate, and efficient solution for multi-view X-ray/CT registration in orthopedic surgeries, which can be easily combined with tracking systems. By improving registration accuracy and minimizing manual intervention, it enhances intraoperative navigation, contributing to more accurate and effective surgical outcomes in computer-assisted surgery (CAS).
- Health & Medicine > Therapeutic Area (1.00)
- Health & Medicine > Diagnostic Medicine > Imaging (1.00)
- South America > Chile > Santiago Metropolitan Region > Santiago Province > Santiago (0.04)
- North America > United States > Oklahoma > Payne County > Cushing (0.04)
- North America > United States > New York (0.04)
- North America > United States > Michigan > Washtenaw County > Ann Arbor (0.04)
- Health & Medicine > Therapeutic Area > Oncology (1.00)
- Health & Medicine > Therapeutic Area > Neurology (1.00)
- Health & Medicine > Diagnostic Medicine (1.00)
- Asia > China > Hong Kong (0.05)
- North America > United States (0.04)
- Asia > Japan > Honshū > Kantō > Tokyo Metropolis Prefecture > Tokyo (0.04)
- Asia > China > Jiangsu Province > Nanjing (0.04)
Automated Segmentation of Coronal Brain Tissue Slabs for 3D Neuropathology
Ramirez, Jonathan Williams, Zemlyanker, Dina, Deden-Binder, Lucas, Herisse, Rogeny, Pallares, Erendira Garcia, Gopinath, Karthik, Gazula, Harshvardhan, Mount, Christopher, Kozanno, Liana N., Marshall, Michael S., Connors, Theresa R., Frosch, Matthew P., Montine, Mark, Oakley, Derek H., Mac Donald, Christine L., Keene, C. Dirk, Hyman, Bradley T., Iglesias, Juan Eugenio
Advances in image registration and machine learning have recently enabled volumetric analysis of postmortem brain tissue from conventional photographs of coronal slabs, which are routinely collected in brain banks and neuropathology laboratories worldwide. One caveat of this methodology is the requirement of segmentation of the tissue from photographs, which currently requires costly manual intervention. In this article, we present a deep learning model to automate this process. The automatic segmentation tool relies on a U-Net architecture that was trained with a combination of 1,414 manually segmented images of both fixed and fresh tissue, from specimens with varying diagnoses, photographed at two different sites. Automated model predictions on a subset of photographs not seen in training were analyzed to estimate performance compared to manual labels, including both inter- and intra-rater variability. Our model achieved a median Dice score over 0.98, mean surface distance under 0.4mm, and 95\% Hausdorff distance under 1.60mm, which approaches inter-/intra-rater levels. Our tool is publicly available at surfer.nmr.mgh.harvard.edu/fswiki/PhotoTools.
- North America > United States > Washington > King County > Seattle (0.14)
- North America > United States > Massachusetts > Suffolk County > Boston (0.04)
- Europe > United Kingdom > England > Cambridgeshire > Cambridge (0.04)
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- Research Report > New Finding (0.46)
- Research Report > Experimental Study (0.46)