Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes of the brain. Alzheimer's disease requires diagnosis by a detailed assessment of MRI scans and neuropsychological tests of the patients. This project compares existing deep learning models in the pursuit of enhancing the accuracy and efficiency of AD diagnosis, specifically focusing on the Convolutional Neural Network, Bayesian Convolutional Neural Network, and the U-net model with the Open Access Series of Imaging Studies brain MRI dataset. Besides, to ensure robustness and reliability in the model evaluations, we address the challenge of imbalance in data. We then perform rigorous evaluation to determine strengths and weaknesses for each model by considering sensitivity, specificity, and computational efficiency. This comparative analysis would shed light on the future role of AI in revolutionizing AD diagnostics but also paved ways for future innovation in medical imaging and the management of neurodegenerative diseases.

This study emphasizes the domain of requirements engineering by applying the SMOTE-Tomek preprocessing technique, combined with stratified K-fold cross-validation, to address class imbalance in the PROMISE dataset. This dataset comprises 969 categorized requirements, classified into functional and non-functional types. The proposed approach enhances the representation of minority classes while maintaining the integrity of validation folds, leading to a notable improvement in classification accuracy. Logistic regression achieved 76.16\%, significantly surpassing the baseline of 58.31\%. These results highlight the applicability and efficiency of machine learning models as scalable and interpretable solutions.