Cardiovascular diseases (CVDs) encompass a group of disorders affecting the heart and blood vessels, including conditions such as coronary artery disease, heart failure, stroke, and hypertension. In cardiovascular diseases, heart failure is one of the main causes of death and also long-term suffering in patients worldwide. Prediction is one of the risk factors that is highly valuable for treatment and intervention to minimize heart failure. In this work, an attention learning-based heart failure prediction approach is proposed on EHR(electronic health record) cardiovascular data such as ejection fraction and serum creatinine. Moreover, different optimizers with various learning rate approaches are applied to fine-tune the proposed approach. Serum creatinine and ejection fraction are the two most important features to predict the patient's heart failure. The computational result shows that the RMSProp optimizer with 0.001 learning rate has a better prediction based on serum creatinine. On the other hand, the combination of SGD optimizer with 0.01 learning rate exhibits optimum performance based on ejection fraction features. Overall, the proposed attention learning-based approach performs very efficiently in predicting heart failure compared to the existing state-of-the-art such as LSTM approach.

Cardiovascular diseases kill approximately 17 million people globally every year, and they mainly exhibit as myocardial infarctions and heart failures. Heart failure (HF) occurs when the heart cannot pump enough blood to meet the needs of the body.Available electronic medical records of patients quantify symptoms, body features, and clinical laboratory test values, which can be used to perform biostatistics analysis aimed at highlighting patterns and correlations otherwise undetectable by medical doctors. Machine learning, in particular, can predict patients’ survival from their data and can individuate the most important features among those included in their medical records. In this paper, we analyze a dataset of 299 patients with heart failure collected in 2015. We apply several machine learning classifiers to both predict the patients survival, and rank the features corresponding to the most important risk factors. We also perform an alternative feature ranking analysis by employing traditional biostatistics tests, and compare these results with those provided by the machine learning algorithms. Since both feature ranking approaches clearly identify serum creatinine and ejection fraction as the two most relevant features, we then build the machine learning survival prediction models on these two factors alone. Our results of these two-feature models show not only that serum creatinine and ejection fraction are sufficient to predict survival of heart failure patients from medical records, but also that using these two features alone can lead to more accurate predictions than using the original dataset features in its entirety. We also carry out an analysis including the follow-up month of each patient: even in this case, serum creatinine and ejection fraction are the most predictive clinical features of the dataset, and are sufficient to predict patients’ survival. This discovery has the potential to impact on clinical practice, becoming a new supporting tool for physicians when predicting if a heart failure patient will survive or not. Indeed, medical doctors aiming at understanding if a patient will survive after heart failure may focus mainly on serum creatinine and ejection fraction.

When GENTAMICIN is given for MENINGITIS, the recommended dosage is: if age is 2 yrs then 1.7 mg/kg q8h IV plus consider giving 5 mg q24h IT, else 2.3 mg/kg q8h IV plus consider giving 2.5-4 rag/day IT. The normal dose for John Jones is: 119 mg (3.0 ml, 80mg/2ml ampule) q8h [calculated on the basis of 1.7 mg/kg] plus consider giving 5 mg q24h IT GENTAMICIN is excreted by the kidneys, so its dosage must be modified in renal failure. The following table shows how the patient's renal function was determined: Identifier Value Definition SCR1 1.9 the most recent serum creatinine (mg/100ml) SCR2 1.8 the previous serum creatinine (mg/100ml) CCr(f) 42.7 estimated creatinine clearance, adjusted for normal body surface area (ml/min/1.73