Specialized Explanations for Dosage Selection

When GENTAMICIN is given for MENINGITIS, the recommended dosage is: if age is 2 yrs then 1.7 mg/kg q8h IV plus consider giving 5 mg q24h IT, else 2.3 mg/kg q8h IV plus consider giving 2.5-4 rag/day IT. The normal dose for John Jones is: 119 mg (3.0 ml, 80mg/2ml ampule) q8h [calculated on the basis of 1.7 mg/kg] plus consider giving 5 mg q24h IT GENTAMICIN is excreted by the kidneys, so its dosage must be modified in renal failure. The following table shows how the patient's renal function was determined: Identifier Value Definition SCR1 1.9 the most recent serum creatinine (mg/100ml) SCR2 1.8 the previous serum creatinine (mg/100ml) CCr(f) 42.7 estimated creatinine clearance, adjusted for normal body surface area (ml/min/1.73