Brain tumor represents one of the most fatal cancers around the world, and is very common in children and the elderly. Accurate identification of the type and grade of tumor in the early stages plays an important role in choosing a precise treatment plan. The Magnetic Resonance Imaging (MRI) protocols of different sequences provide clinicians with important contradictory information to identify tumor regions. However, manual assessment is time-consuming and error-prone due to big amount of data and the diversity of brain tumor types. Hence, there is an unmet need for MRI automated brain tumor diagnosis. We observe that the predictive capability of uni-modality models is limited and their performance varies widely across modalities, and the commonly used modality fusion methods would introduce potential noise, which results in significant performance degradation. To overcome these challenges, we propose a novel cross-modality guidance-aided multi-modal learning with dual attention for addressing the task of MRI brain tumor grading. To balance the tradeoff between model efficiency and efficacy, we employ ResNet Mix Convolution as the backbone network for feature extraction. Besides, dual attention is applied to capture the semantic interdependencies in spatial and slice dimensions respectively. To facilitate information interaction among modalities, we design a cross-modality guidance-aided module where the primary modality guides the other secondary modalities during the process of training, which can effectively leverage the complementary information of different MRI modalities and meanwhile alleviate the impact of the possible noise.

Medical applications have benefited greatly from the rapid advancement in computer vision. Considering patient monitoring in particular, in-bed human posture estimation offers important health-related metrics with potential value in medical condition assessments. Despite great progress in this domain, it remains challenging due to substantial ambiguity during occlusions, and the lack of large corpora of manually labeled data for model training, particularly with domains such as thermal infrared imaging which are privacy-preserving, and thus of great interest. Motivated by the effectiveness of self-supervised methods in learning features directly from data, we propose a multi-modal conditional variational autoencoder (MC-VAE) capable of reconstructing features from missing modalities seen during training. This approach is used with HRNet to enable single modality inference for in-bed pose estimation. Through extensive evaluations, we demonstrate that body positions can be effectively recognized from the available modality, achieving on par results with baseline models that are highly dependent on having access to multiple modes at inference time. The proposed framework supports future research towards self-supervised learning that generates a robust model from a single source, and expects it to generalize over many unknown distributions in clinical environments.