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Venom and Hot Peppers Offer a Key to Killing Resistant Bacteria
Researchers have developed three new antibiotics from scorpion venom and habanero peppers to combat tuberculosis and other drug-resistant pathogens. Researchers from the National Autonomous University of Mexico (UNAM) have identified new ways to combat tuberculosis and reduce bacterial resistance, developing three new antibiotics derived from scorpion venom and habanero peppers. A team led by Lourival Domingos Possani Postay, from the Institute of Biotechnology's Morelos campus, created two drugs that demonstrated efficacy against the bacterium, responsible for tuberculosis, as well as against, a microorganism that in hospital environments can cause various clinical complications, from skin infections to potentially fatal diseases such as pneumonia, meningitis, septicemia, and endocarditis. The antibiotics were derived from the venom of the scorpion, native to the state of Veracruz. The team was able to isolate two colorless molecules called benzoquinones--heterocyclic compounds that do not contain amino acids--from the arachnid's toxin.
The Download: inside the Musk v. Altman trial, and AI for democracy
Plus: The Pentagon has struck sweeping AI deals for classified work. Week one of the Musk v. Altman trial: what it was like in the room Two of the most powerful figures in AI--Sam Altman and Elon Musk--are in the middle of a landmark legal showdown, with Musk alleging he was misled about OpenAI becoming a for-profit company. Our reporter Michelle Kim, who also happens to be a lawyer, has been in court each day, and has broken down the first week's key moments in her latest report . In a new Q&A, she also reveals what it was like in the room, the new details that have emerged about how Musk and OpenAI operate--and what we can expect from this week's proceedings. Find out what she's discovered so far, and if you want to keep up with MIT Technology Review's ongoing coverage of the Musk v. Altman trial, follow @techreview or @michelletomkim on X. Faster than many realize, AI is becoming the primary interface through which we form beliefs and participate in democratic self-governance. This shift could further strain already fragile institutions, but it could also help address problems like polarization and declining civic engagement.
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The Next Alzheimer's Breakthrough Will Take More Than Just Science
The Next Alzheimer's Breakthrough Will Take More Than Just Science At WIRED Health, pioneering Alzheimer's researcher John Hardy outlined the stakes--and next steps--of where treatment is headed next. Alzheimer's research is entering a new phase, as treatments that have taken decades to develop begin to reach patients . But getting those advances to people will depend on more than scientific progress alone, according to pioneering Alzheimer's researcher John Hardy . Speaking at WIRED Health in April, Hardy, chair of the Molecular Biology of Neurological Disease at University College London, said that alongside more effective drugs, better diagnosis and political will were still needed to improve treatment of Alzheimer's disease. "We've got to get better," he said.
How time travel could work: Scientists have uncovered a way to send messages into the PAST
TPUSA issues blistering response to Hollywood nepo baby who called Erika Kirk a'sociopath' and urged Trump to'kill' organization Who's The Boss? star Judith Light, 77, has fans concerned with strange poses on red carpet Shock as Home Depot rival closes all 15 of its stores and declares bankruptcy thanks to consumers' reluctance to spend ROBERT HARDMAN: What Trump told me about the King and William. Men everywhere secretly have the same complaint about their sex lives. It's NOT about looks or frequency... Spirit Airlines prepares to shut down as Trump's rescue deal falls apart I'm the REAL Emily from Devil Wears Prada: Anna Wintour's assistant played by Emily Blunt reveals herself... and cutthroat behind-scenes details that the movie did NOT include The Devil Wears Prada 2 review: Searingly silly, ridiculous sequel is a complete disgrace to fashion... and guilty of the biggest sin of all: JANE TIPPETT The ultimate Ozempic survival kit: Experts reveal cheap drugstore remedies and one miracle food every GLP-1 user needs to ease side effects... meaning you can take a HIGHER dose and lose MORE weight Mom stunned to discover she is pregnant with twins just WEEKS after giving birth: 'I was in denial' Alleged JPMorgan sex slave unmasked as crisis sparks drama at America's biggest bank: 'Everyone's wondering what Jamie thinks' Time machines may seem better suited to science fiction than the physics lab, but experts say this futuristic technology could become a reality. Researchers have revealed how time travel could really work by using the laws of quantum physics. While their method won't let you hop back to the time of the dinosaurs, scientists say it could be possible to send messages into the past.
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AI for Science – from cosmology to chemistry
On the 31st March, our editorial team headed to the Royal Society for AI for Science . This day-long conference explored how AI is changing the nature of scientific discovery, and was hosted by the Fundamental Research team from the Alan Turing Institute. Nestled in a terrace of 19th century townhouses along the banks of the Thames, the Royal Society looks as grand as the names who have passed through its doors throughout the years. Prof Jason McEwen, Chief Scientist for the Turing Institute, opened the event with an insightful talk on the nature of scientific revolution, and how the bidirectional relationship between AI and science could spark the next one. Then, Prof Anna Scaife from the University of Manchester spoke on the use of foundation models for astronomical discovery.
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Trump's mass firing just dealt another blow to American science
Trump's mass firing just dealt another blow to American science Ambitious research is on the chopping block following yet more cuts at the National Science Foundation. This past week delivered another gut punch for science in the US. This time, the target was the National Science Foundation--a federal agency that funds major research projects to the tune of around $9 billion. The foundation's efforts were overseen by a board of 22 prominent scientists. On Friday last week, they were all fired . The NSF has been without a director since April 2025, when former director Sethuraman Panchanathan stepped down in the wake of DOGE-led funding cuts and mass firings.
Scientists Are Starting to Unlock the Nanoscale Secrets of the Immune System
At WIRED Health, immunologist Daniel Davis detailed the ways in which new technologies are enabling a better understanding of the human immune system. The immune system operates at a scale scientists are only just beginning to be able to see. That new view could change how diseases like cancer are tackled. Speaking at WIRED Health on April 16, Daniel Davis, an immunologist at Imperial College London, detailed how researchers are using advanced microscopes to uncover previously invisible dynamics in the human immune system, showing that there are multiple processes happening on a "nanoscale" that was previously out of reach. That new view is already reshaping how immunity is understood.
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The Download: the North Pole's future and humanoid data
Plus: Google, Microsoft, Amazon and Meta have all set AI spending records. In the past, getting to the North Pole involved a treacherous trip through ice many meters thick. But last year, a research vessel encountered open water and thin ice, which created an easy passage. It provided a reminder of how quickly the Arctic is changing. Now scientists are digging deep below the seabed to find out if the Arctic Ocean was ever ice-free--and what that could mean for the future of Earth's northernmost waters. Here's what they hope to discover .
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Robot goes rogue at school sports day: Dancing humanoid is dragged away by handlers after malfunctioning in front of shocked students
Fury as NYC on course to join Detroit, Chicago and Puerto Rico with woke mayor Mamdani's latest reckless plan Hidden $65bn lithium motherlode mapped beneath America's oldest mountains could power nation for centuries A quarter of US stock market gets report cards from Wall Street on same day this week. Even one bad grade can spell catastrophe for your 401(k). Here's EXACTLY what you need to do I was constantly burned out and kept cancelling plans because I was so tired. Doctors said it was just hormones... then I was diagnosed with this aggressive cancer. Nicole Kidman's daughters have'CUT OFF' dad Keith Urban: Insiders reveal why they are'SO angry'... and how he is utterly'distraught' but finally admitting'guilt' Florida go-kart park ordered to pay hefty settlement after mom and daughter, 6, broke two important rules that resulted in little girl's death King Charles leaves White House roaring with laughter with jokes to Trump about'speaking French' and the Boston Tea Party in dazzling state dinner Brace for the'Big Crunch': Scientists predict when the universe will end - and it's TRILLIONS of years sooner than we thought The $1.50 fruit that can protect you from deadly heart disease Why Donald Trump Jr and Bettina Anderson's wedding is'on hold' just weeks after extravagant'enchanted garden' bridal shower Serena Williams leaves fans split with controversial parenting confession as tennis legend opens up on'discipline' incident with daughter'No more Mr Nice Guy!': Trump warns Iran to'get smart' and'sign non-nuclear deal' with image of him brandishing assault rifle - as oil prices spike once more The surprise state cashing in big as Californians flee in droves... and the $672-a-month reason why What REALLY goes on in some Equinox steam rooms: Gym insiders reveal eye-popping indecency... secret towel signals used by experimental married men... and clubs with most'aggressive' locker rooms Fox News's Jesse Watters, 47, takes his young wife, 33, to state dinner after causing stir with story of how he seduced her Truth about Jordan Peterson's catastrophic decline: Inside his living hell, dumbstruck and in'overwhelming pain' locked up on $50m estate... as friends point finger about REAL cause Worrying shift as restaurant chain rolls out no-seating stores - sparking fears this is just the start of a'corporate purge of the American dining room' Shocking footage has revealed the moment a dancing robot went rogue at a school sports day.
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The UK's Answer to Darpa Wants to Rewire the Human Brain
ARIA has a billion-dollar budget and big aspirations for tackling everything from epilepsy to Alzheimer's. The UK's Advanced Research and Innovation Agency (ARIA) was established in 2023 with the goal of pursuing "high-risk, high-reward" moonshots in sectors ranging from bolstering food security to new ways of ramping up human immunity . With more than £1 billion (about $1.3 billion) worth of government funding earmarked between now and 2030, one of ARIA's most ambitious programs is a £69 million initiative that aims to develop more tailored ways of modulating the human brain. The hope is to eventually address an entire range of disorders, from epilepsy to Alzheimer's. Reports have previously estimated that this suite of neurological conditions costs the UK economy tens of billions of dollars each year.
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