Things to Do in L.A. Tap to enable a layout that focuses on the article. Trump administration seeks to limit federal funding that doesn't'advance' presidential policies The White House Office of Management and Budget has proposed sweeping new rules for the way federal grants are awarded and overseen. This is read by an automated voice. Please report any issues or inconsistencies here . See more from the L.A. Times in Google Search.

England and Norway players will face off under extreme and dangerous levels of heat stress, scientists say, thanks to a Wet Bulb Index of nearly 90 F. For Norway's national men's soccer team, Saturday's World Cup quarter-final against England will be a first in more ways than one. As the Scandinavian side prepares for the biggest match of its history, it will also face conditions almost unimaginable back home: the punishing combination of South Florida heat, humidity, and blazing sunshine that scientists warn can push the human body to its limits. South Florida's mix of strong sun, hot-air temperature, and high humidity--boosted by a plume of dusty air from the Sahara desert sweeping across the Atlantic through the state--will put the northern European players under a level of heat stress rarely experienced in their native countries. Scientists quantify this heat stress by calculating the WetBulb Globe Temperature. On top of air temperature, the index takes into account humidity, which limits evaporation of sweat from the skin; wind, which can act as a coolant; and solar intensity, as sunshine directly raises individuals' skin and core temperatures.

Plus: NATO is building a network to stop Russian attackers in their tracks. I was really looking forward to July 4, and not just because I love a poolside barbecue. This year the American holiday also marked a big symbolic deadline for US nuclear power. Last year the Trump administration set a goal to see three new microreactors achieve criticality, a technical milestone establishing that a reactor can sustain a chain reaction, by the nation's 250th birthday. And just in time, not just three, but four reactors did so. But achieving criticality doesn't mean a reactor is ready to provide electricity for the grid (or at all, for that matter).

Occam's razor has lost its edge. Can we sharpen our search for truth? Seeking out the simplest, most elegant explanations has served scientists well for centuries, but cognitive scientist Marina Dubova's experiments are revealing better ways to uncover reality Limited by the knowledge of his time, the ancient Greek astronomer Ptolemy imagined that the planets and sun of our solar system orbited Earth. Every new observation that pushed against this image required a slight tweak to that theory, until centuries later Nicolaus Copernicus's reimagining toppled it once and for all. A more elegant explanation proposed that all the planets orbited the sun, kicking off a scientific revolution that changed our understanding of the entire universe.

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The Download: a startup has a solution for AI's groupthink problem Plus: Scientists say they have built a cell from scratch for the first time. LLMs are stuck in a groupthink groove. This startup is trying to get them out. Open up your chatbot of choice--Claude, ChatGPT, Gemini--and type "Give me a random number between 1 and 10." You're going to get 7. Almost always. That won't work every time--but if it did for you, you may wonder if I have superpowers. The truth is that most large language models are stuck in a rut.

At an event for pharmaceutical executives, biotech founders, and researchers on Tuesday, Anthropic announced Claude Science, a major new product intended to support scientific research in the same way that Claude Code supports software engineering. Like Claude Code, Claude Science can autonomously carry out meaningful work when given concise, high-level instructions, and it has access to tools that make it particularly useful for research in computational biology and drug development. Along with launching and previewing Claude Science, which is now available to all paid Claude subscribers, Anthropic also announced that it will be using the product to pursue some of its own research into drugs for rare, neglected diseases. This is not Anthropic's first foray into AI for science. In October, the company released plug-ins that help Claude make use of scientific software and databases under the heading "Claude for Life Sciences." But unlike this earlier release, Claude Science is a full-featured, standalone product. Anthropic's decision to elevate Claude Science to the same rank as Claude Code and Claude Cowork indicates that the company is taking AI's scientific applications very seriously--or at least wants to give the impression that it is.

The maps and images show the extent of destruction and give rescue operations a tool to find any remaining survivors. A satellite image from Vantor shows collapsed apartment buildings and widespread damage caused by the earthquake in the Playa Grande neighborhood of La Guaira. Satellite Technology Is being used to streamline rescue efforts in Venezuela following the two earthquakes that struck on June 24. Space agencies have shared images with emergency authorities and the Venezuelan government that not only reveal the magnitude of the disaster but also allow response teams to identify where to focus their efforts--and the challenges on the ground. Following the twin earthquakes in Venezuela, the Copernicus satellite system activated its emergency mapping mode at the request of the European Commission's Directorate-General for Civil Protection and Humanitarian Aid Operations.

Plus: The Trump administration has asked OpenAI to limit its next model release. Scientists are trying to figure out why. It's been hot in London this week. A dangerous heat wave has hit Western Europe. On Wednesday, the UK recorded its highest ever June temperature at 36.1 C (about 97 F). But as the weather app on my phone confirmed, it 39 C. Much of Western Europe is suffering, bringing awful consequences for agriculture, infrastructure, and the health system.

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins. When molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter cellular behavior. Understanding how proteins fold and move is therefore essential for developing drugs that interact well with their targets. Artificial intelligence (AI) is a very useful tool to generate novel protein structures, but most systems - including Google DeepMind's AlphaFold - focus on producing static'snapshots' of proteins. Subtle rearrangements of atoms in structures called side chains, which influence a protein's interactions with other molecules, are not captured.