We study the problem of estimating ap-dimensional s-sparse vector in a linear model with Gaussian design and additivenoise.

Calcium imaging is a prominent technology in neuroscience research which allows for simultaneous recording of large numbers of neurons in awake animals. Automated extraction of neurons and their temporal activity from imaging datasets is an important step in the path to producing neuroscience results. However, nearly all imaging datasets contain gross contaminating sources which could originate from the technology used, or the underlying biological tissue. Although past work has considered the effects of contamination under limited circumstances, there has not been a general framework treating contamination and its effects on the statistical estimation of calcium signals. In this work, we proceed in a new direction and propose to extract cells and their activity using robust statistical estimation. Using the theory of M-estimation, we derive a minimax optimal robust loss, and also find a simple and practical optimization routine for this loss with provably fast convergence. We use our proposed robust loss in a matrix factorization framework to extract the neurons and their temporal activity in calcium imaging datasets. We demonstrate the superiority of our robust estimation approach over existing methods on both simulated and real datasets.

This study introduces an integrated framework for predictive causal inference designed to overcome limitations inherent in conventional single model approaches. Specifically, we combine a Hidden Markov Model (HMM) for spatial health state estimation with a Multi Task and Multi Graph Convolutional Network (MTGCN) for capturing temporal outcome trajectories. The framework asymmetrically treats temporal and spatial information regarding them as endogenous variables in the outcome regression, and exogenous variables in the propensity score model, thereby expanding the standard doubly robust treatment effect estimation to jointly enhance bias correction and predictive accuracy. To demonstrate its utility, we focus on clinical domains such as cancer, dementia, and Parkinson disease, where treatment effects are challenging to observe directly. Simulation studies are conducted to emulate latent disease dynamics and evaluate the model performance under varying conditions. Overall, the proposed framework advances predictive causal inference by structurally adapting to spatiotemporal complexities common in biomedical data.

There is growing interest in developing statistical estimators that achieve exponential concentration around a population target even when the data distribution has heavier than exponential tails. More recent activity has focused on extending such ideas beyond Euclidean spaces to Hilbert spaces and Riemannian manifolds. In this work, we show that such exponential concentration in presence of heavy tails can be achieved over a broader class of parameter spaces called CAT($\kappa$) spaces, a very general metric space equipped with the minimal essential geometric structure for our purpose, while being sufficiently broad to encompass most typical examples encountered in statistics and machine learning. The key technique is to develop and exploit a general concentration bound for the Fr\'echet median in CAT($\kappa$) spaces. We illustrate our theory through a number of examples, and provide empirical support through simulation studies.

--This paper utilizes the properties of type-based multiple access (TBMA) to investigate its effectiveness as a robust approach for over-the-air computation (AirComp) in the presence of Byzantine attacks, this is, adversarial strategies where malicious nodes intentionally distort their transmissions to corrupt the aggregated result. Unlike classical direct aggregation (DA) AirComp, which aggregates data in the amplitude of the signals and are highly vulnerable to attacks, TBMA distributes data over multiple radio resources, enabling the receiver to construct a histogram representation of the transmitted data. This structure allows the integration of classical robust estimators and supports the computation of diverse functions beyond the arithmetic mean, which is not feasible with DA. Through extensive simulations, we demonstrate that robust TBMA significantly outperforms DA, maintaining high accuracy even under adversarial conditions, and showcases its applicability in federated learning (FEEL) scenarios. Additionally, TBMA reduces channel state information (CSI) requirements, lowers energy consumption, and enhances resiliency by leveraging the diversity of the transmitted data. These results establish TBMA as a scalable and robust solution for AirComp, paving the way for secure and efficient aggregation in next-generation networks. The advent of highly complex and heterogeneous networks has created an urgent need for high-speed data transfer protocols capable of handling massive data volumes while enabling real-time processing and data-driven decision-making.