Nonlinear mixed-effects models are widely used to analyze longitudinal data, but existing open-source software often supports only a limited subset of the model structures, inference methods, machine-learning components, automatic differentiation techniques, and random-effects distributions required in modern applications. We introduce NoLimits.jl, an open-source Julia package for flexible and composable nonlinear mixed-effects modeling. Its macro-based modeling language enables observation and latent-state models to be constructed from diverse building blocks, including ordinary differential equations, Markov models, and neural networks. NoLimits.jl supports flexible, covariate-dependent observation and random-effects distributions and provides a unified interface to frequentist inference through Laplace approximation, stochastic expectation maximization, and Bayesian Markov chain Monte Carlo methods. We demonstrate the package on three case studies showcasing its workflows, integration of differentiable machine-learning components, and data-driven estimation of random-effects distributions using normalizing flows. Together, these capabilities substantially expand the range of nonlinear mixed-effects models that can be specified, estimated, and compared within a single open-source framework.

Conventional models prepare a large embedding matrix whose size depends on the vocabulary size. Therefore, storing these models in memory and disk storage is costly.

We describe the translation of the Suggested Upper Merged Ontology (SUMO) to Typed First-order Form (TFF) with level 0 polymorphism. Building on our prior work to create a TPTP FOF translation of SUMO for use in the E and Vampire theorem provers, we detail the transformations required to handle an explicitly typed logic, and express SUMO's type hierarchy for numbers in a manner consistent with its intended semantics and the three numerical classes allowed in TFF. We provide description of the open source code and an example proof in Vampire on the resulting theory.