Scientists looking to create a new generation of supercomputers are looking for inspiration from the most complex and energy-efficient computer ever built: the human brain. In some of their initial forays into making brain-inspired computers, researchers are looking at different nonbiological materials whose properties could be tailored to show evidence of learning-like behaviors. These materials could form the basis for hardware that could be paired with new software algorithms to enable more potent, useful and energy-efficient artificial intelligence (AI). In a new study led by scientists from Purdue University, researchers have exposed oxygen deficient nickel oxide to brief electrical pulses and elicited two different electrical responses that are similar to learning. The result is an all-electrically-driven system that shows these learning behaviors, said Rutgers University professor Shriram Ramanathan.

When the human brain learns something new, it adapts. But when artificial intelligence learns something new, it tends to forget information it already learned. As companies use more and more data to improve how AI recognizes images, learns languages and carries out other complex tasks, a paper published in Science this week shows a way that computer chips could dynamically rewire themselves to take in new data like the brain does, helping AI to keep learning over time. "The brains of living beings can continuously learn throughout their lifespan. We have now created an artificial platform for machines to learn throughout their lifespan," said Shriram Ramanathan, a professor in Purdue University's School of Materials Engineering who specializes in discovering how materials could mimic the brain to improve computing.

Artificial intelligence (AI) could soon get a boost from a new type of computer chips inspired by the human brain. Researchers at Purdue University have built a new piece of hardware that can be reprogrammed on demand through electrical pulses. The team claims that this adaptability would allow the device to take on all of the necessary functions to build a brain-inspired computer. It's part of an ongoing effort to build AI systems that can learn continuously. "When AI systems learn continually in the environment, they can adapt to a world that changes over time," Stevens Institute of Technology AI expert Jordan Suchow told Lifewire in an email interview.

WHEN the human brain learns something new, it adapts. But when artificial intelligence learns something new, it tends to forget information it already learned. As companies use more and more data to improve how AI recognizes images, learns languages and carries out other complex tasks, a paper published in Science this week shows a way that computer chips could dynamically rewire themselves to take in new data like the brain does, helping AI to keep learning over time. "The brains of living beings could continuously learn throughout their lifespan. We have now created an artificial platform for machines to learn throughout their lifespan," said Shriram Ramanathan, a professor in Purdue University's School of Materials Engineering who specializes in discovering how materials could mimic the brain to improve computing.

As companies use more and more data to improve how AI recognizes images, learns languages and carries out other complex tasks, a paper publishing in Science this week shows a way that computer chips could dynamically rewire themselves to take in new data like the brain does, helping AI to keep learning over time. "The brains of living beings can continuously learn throughout their lifespan. We have now created an artificial platform for machines to learn throughout their lifespan," said Shriram Ramanathan, a professor in Purdue University's School of Materials Engineering who specializes in discovering how materials could mimic the brain to improve computing. Unlike the brain, which constantly forms new connections between neurons to enable learning, the circuits on a computer chip don't change. A circuit that a machine has been using for years isn't any different than the circuit that was originally built for the machine in a factory.

When the human brain learns something new, it adapts. But when artificial intelligence learns something new, it tends to forget information it already learned. As companies use more and more data to improve how AI recognizes images, learns languages and carries out other complex tasks, a paper publishing in Science this week shows a way that computer chips could dynamically rewire themselves to take in new data like the brain does, helping AI to keep learning over time. "The brains of living beings can continuously learn throughout their lifespan. We have now created an artificial platform for machines to learn throughout their lifespan," said Shriram Ramanathan, a professor in Purdue University's School of Materials Engineering who specializes in discovering how materials could mimic the brain to improve computing.

Neonatal respiratory distress is a common condition that if left untreated, can lead to short- and long-term complications. This paper investigates the usage of digital stethoscope recorded chest sounds taken within 1min post-delivery, to enable early detection and prediction of neonatal respiratory distress. Fifty-one term newborns were included in this study, 9 of whom developed respiratory distress. For each newborn, 1min anterior and posterior recordings were taken. These recordings were pre-processed to remove noisy segments and obtain high-quality heart and lung sounds. The random undersampling boosting (RUSBoost) classifier was then trained on a variety of features, such as power and vital sign features extracted from the heart and lung sounds. The RUSBoost algorithm produced specificity, sensitivity, and accuracy results of 85.0%, 66.7% and 81.8%, respectively.

Published in Oct. in the Journal of Pharmacokinetics and Pharmacodynamics, the model assesses metabolic and cardiovascular biomarkers – measurable biological processes such as cholesterol levels, body mass index, glucose and blood pressure – to calculate health status and disease risks across a patient's lifespan. The findings are critical due to the increased risk of developing metabolic and cardiovascular diseases with aging, a process that has adverse effects on cellular, psychological and behavioral processes. "There is an unmet need for scalable approaches that can provide guidance for pharmaceutical care across the lifespan in the presence of aging and chronic co-morbidities," says lead author Murali Ramanathan, PhD, professor of pharmaceutical sciences in the UB School of Pharmacy and Pharmaceutical Sciences. "This knowledge gap may be potentially bridged by innovative disease progression modeling." The model could facilitate the assessment of long-term chronic drug therapies, and help clinicians monitor treatment responses for conditions such as diabetes, high cholesterol and high blood pressure, which become more frequent with age, says Ramanathan.

In its on-going campaign to reveal the inner workings of the SARS-CoV-2 virus, the U.S. Department of Energy's (DOE) Argonne National Laboratory is leading efforts to couple artificial intelligence (AI) and cutting-edge simulation workflows to better understand biological observations and accelerate drug discovery. Argonne collaborated with academic and commercial research partners to achieve near real-time feedback between simulation and AI approaches to understand how two proteins in the SARS-CoV-2 viral genome, nsp10 and nsp16, interact to help the virus replicate and elude the host's immune system. The team achieved this milestone by coupling two distinct hardware platforms: Cerebras CS-1, a processor-packed silicon wafer deep learning accelerator; and ThetaGPU, an AI- and simulation-enabled extension of the Theta supercomputer, housed at the Argonne Leadership Computing Facility, a DOE Office of Science User Facility. To enable this capability, the team developed Stream-AI-MD, a novel application of the AI method called deep learning to drive adaptive molecular dynamics (MD) simulations in a streaming manner. Data from simulations is streamed from ThetaGPU onto the Cerebras CS-1 platform to simultaneously analyze how the two proteins interact.

In its on-going campaign to reveal the inner workings of the Sar-CoV-2 virus, the U.S. Department of Energy's (DOE) Argonne National Laboratory is leading efforts to couple artificial intelligence (AI) and cutting-edge simulation workflows to better understand biological observations and accelerate drug discovery. Argonne collaborated with academic and commercial research partners to achieve near real-time feedback between simulation and AI approaches to understand how two proteins in the SARS-CoV-2 viral genome, nsp10 and nsp16, interact to help the virus replicate and elude the host's immune system. The team achieved this milestone by coupling two distinct hardware platforms: Cerebras CS-1, a processor-packed silicon wafer deep learning accelerator; and ThetaGPU, an AI- and simulation-enabled extension of the Theta supercomputer, housed at the Argonne Leadership Computing Facility, a DOE Office of Science User Facility. To enable this capability, the team developed Stream-AI-MD, a novel application of the AI method called deep learning to drive adaptive molecular dynamics (MD) simulations in a streaming manner. Data from simulations is streamed from ThetaGPU onto the Cerebras CS-1 platform to simultaneously analyze how the two proteins interact.