Preservation of private user data is of paramount importance for high Quality of Experience (QoE) and acceptability, particularly with services treating sensitive data, such as IT-based health services. Whereas anonymization techniques were shown to be prone to data re-identification, synthetic data generation has gradually replaced anonymization since it is relatively less time and resource-consuming and more robust to data leakage. Generative Adversarial Networks (GANs) have been used for generating synthetic datasets, especially GAN frameworks adhering to the differential privacy phenomena. This research compares state-of-the-art GAN-based models for synthetic data generation to generate time-series synthetic medical records of dementia patients which can be distributed without privacy concerns. Predictive modeling, autocorrelation, and distribution analysis are used to assess the Quality of Generating (QoG) of the generated data. The privacy preservation of the respective models is assessed by applying membership inference attacks to determine potential data leakage risks. Our experiments indicate the superiority of the privacy-preserving GAN (PPGAN) model over other models regarding privacy preservation while maintaining an acceptable level of QoG. The presented results can support better data protection for medical use cases in the future.

Generative Adversarial Network (GAN) and its variants serve as a perfect representation of the data generation model, providing researchers with a large amount of high-quality generated data. They illustrate a promising direction for research with limited data availability. When GAN learns the semantic-rich data distribution from a dataset, the density of the generated distribution tends to concentrate on the training data. Due to the gradient parameters of the deep neural network contain the data distribution of the training samples, they can easily remember the training samples. When GAN is applied to private or sensitive data, for instance, patient medical records, as private information may be leakage. To address this issue, we propose a Privacy-preserving Generative Adversarial Network (PPGAN) model, in which we achieve differential privacy in GANs by adding well-designed noise to the gradient during the model learning procedure. Besides, we introduced the Moments Accountant strategy in the PPGAN training process to improve the stability and compatibility of the model by controlling privacy loss. We also give a mathematical proof of the differential privacy discriminator. Through extensive case studies of the benchmark datasets, we demonstrate that PPGAN can generate high-quality synthetic data while retaining the required data available under a reasonable privacy budget.