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Patient-Centric Knowledge Graphs: A Survey of Current Methods, Challenges, and Applications

Khatib, Hassan S. Al, Neupane, Subash, Manchukonda, Harish Kumar, Golilarz, Noorbakhsh Amiri, Mittal, Sudip, Amirlatifi, Amin, Rahimi, Shahram

arXiv.org Artificial Intelligence

Patient-Centric Knowledge Graphs (PCKGs) represent an important shift in healthcare that focuses on individualized patient care by mapping the patient's health information in a holistic and multi-dimensional way. PCKGs integrate various types of health data to provide healthcare professionals with a comprehensive understanding of a patient's health, enabling more personalized and effective care. This literature review explores the methodologies, challenges, and opportunities associated with PCKGs, focusing on their role in integrating disparate healthcare data and enhancing patient care through a unified health perspective. In addition, this review also discusses the complexities of PCKG development, including ontology design, data integration techniques, knowledge extraction, and structured representation of knowledge. It highlights advanced techniques such as reasoning, semantic search, and inference mechanisms essential in constructing and evaluating PCKGs for actionable healthcare insights. We further explore the practical applications of PCKGs in personalized medicine, emphasizing their significance in improving disease prediction and formulating effective treatment plans. Overall, this review provides a foundational perspective on the current state-of-the-art and best practices of PCKGs, guiding future research and applications in this dynamic field.


Probability Aggregates in Probability Answer Set Programming

Saad, Emad

arXiv.org Artificial Intelligence

Probability answer set programming is a declarative programming that has been shown effective for representing and reasoning about a variety of probability reasoning tasks. However, the lack of probability aggregates, e.g. {\em expected values}, in the language of disjunctive hybrid probability logic programs (DHPP) disallows the natural and concise representation of many interesting problems. In this paper, we extend DHPP to allow arbitrary probability aggregates. We introduce two types of probability aggregates; a type that computes the expected value of a classical aggregate, e.g., the expected value of the minimum, and a type that computes the probability of a classical aggregate, e.g, the probability of sum of values. In addition, we define a probability answer set semantics for DHPP with arbitrary probability aggregates including monotone, antimonotone, and nonmonotone probability aggregates. We show that the proposed probability answer set semantics of DHPP subsumes both the original probability answer set semantics of DHPP and the classical answer set semantics of classical disjunctive logic programs with classical aggregates, and consequently subsumes the classical answer set semantics of the original disjunctive logic programs. We show that the proposed probability answer sets of DHPP with probability aggregates are minimal probability models and hence incomparable, which is an important property for nonmonotonic probability reasoning.