This article investigates deep learning methodologies for single-modality clinical data analysis, as a crucial precursor to multi-modal medical research. Building on Guo JingYuan's work, the study refines clinical data processing through Compact Convolutional Transformer (CCT), Patch Up, and the innovative CamCenterLoss technique, establishing a foundation for future multimodal investigations. The proposed methodology demonstrates improved prediction accuracy and at tentiveness to critically ill patients compared to Guo JingYuan's ResNet and StageNet approaches. Novelty that using image-pretrained vision transformer backbone to perform transfer learning time-series clinical data.The study highlights the potential of CCT, Patch Up, and novel CamCenterLoss in processing single modality clinical data within deep learning frameworks, paving the way for future multimodal medical research and promoting precision and personalized healthcare

Large capacity deep learning models are often prone to a high generalization gap when trained with a limited amount of labeled training data. A recent class of methods to address this problem uses various ways to construct a new training sample by mixing a pair (or more) of training samples. We propose PatchUp, a hidden state block-level regularization technique for Convolutional Neural Networks (CNNs), that is applied on selected contiguous blocks of feature maps from a random pair of samples. Our approach improves the robustness of CNN models against the manifold intrusion problem that may occur in other state-of-the-art mixing approaches like Mixup and CutMix. Moreover, since we are mixing the contiguous block of features in the hidden space, which has more dimensions than the input space, we obtain more diverse samples for training towards different dimensions. Our experiments on CIFAR-10, CIFAR-100, and SVHN datasets with PreactResnet18, PreactResnet34, and WideResnet-28-10 models show that PatchUp improves upon, or equals, the performance of current state-of-the-art regularizers for CNNs. We also show that PatchUp can provide better generalization to affine transformations of samples and is more robust against adversarial attacks.