Predicting the outcomes of professional basketball games, particularly in the National Basketball Association (NBA), has become increasingly important for coaching strategy, fan engagement, and sports betting. However, many existing prediction models struggle with concept drift, limited temporal context, and instability across seasons. To advance forecasting in this domain, we introduce a newly constructed longitudinal NBA dataset covering the 2004-05 to 2024-25 seasons and present a deep learning framework designed to model long-term performance trends. Our primary contribution is a Long Short-Term Memory (LSTM) architecture that leverages an extended sequence length of 9,840 games equivalent to eight full NBA seasons to capture evolving team dynamics and season-over-season dependencies. We compare this model against several traditional Machine Learning (ML) and Deep Learning (DL) baselines, including Logistic Regression, Random Forest, Multi-Layer Perceptron (MLP), and Convolutional Neural Network (CNN). The LSTM achieves the best performance across all metrics, with 72.35 accuracy, 73.15 precision and 76.13 AUC-ROC. These results demonstrate the importance of long-sequence temporal modeling in basketball outcome prediction and highlight the value of our new multi-season dataset for developing robust, generalizable NBA forecasting systems.

This study compares baseline (J0) and 24-hour (J1) diffusion magnetic resonance imaging (MRI) for predicting three-month functional outcomes after acute ischemic stroke (AIS). Seventy-four AIS patients with paired apparent diffusion coefficient (ADC) scans and clinical data were analyzed. Three-dimensional ResNet-50 embeddings were fused with structured clinical variables, reduced via principal component analysis (<=12 components), and classified using linear support vector machines with eight-fold stratified group cross-validation. J1 multimodal models achieved the highest predictive performance (AUC = 0.923 +/- 0.085), outperforming J0-based configurations (AUC <= 0.86). Incorporating lesion-volume features further improved model stability and interpretability. These findings demonstrate that early post-treatment diffusion MRI provides superior prognostic value to pre-treatment imaging and that combining MRI, clinical, and lesion-volume features produces a robust and interpretable framework for predicting three-month functional outcomes in AIS patients.

Abstract--This paper introduces HGNN(O), an AutoML GNN hypermodel framework for outcome prediction on event-sequence data. Building on our earlier work on graph convolutional network hypermodels, HGNN(O) extends four architectures--One Level, Two Level, Two Level Pseudo Embedding, and Two Level Embedding--across six canonical GNN operators. A self-tuning mechanism based on Bayesian optimization with pruning and early stopping enables efficient adaptation over architectures and hyperparameters without manual configuration. Empirical evaluation on both balanced and imbalanced event logs shows that HGNN(O) achieves accuracy exceeding 0.98 on the Traffic Fines dataset and weighted F1 scores up to 0.86 on the Patients dataset without explicit imbalance handling. These results demonstrate that the proposed AutoML-GNN approach provides a robust and generalizable benchmark for outcome prediction in complex event-sequence data.

Fine-grained analysis of intraoperative behavior and its impact on patient outcomes remain a longstanding challenge. We present Frame-to-Outcome (F2O), an end-to-end system that translates tissue dissection videos into gesture sequences and uncovers patterns associated with postoperative outcomes. Leveraging transformer-based spatial and temporal modeling and frame-wise classification, F2O robustly detects consecutive short (~2 seconds) gestures in the nerve-sparing step of robot-assisted radical prostatectomy (AUC: 0.80 frame-level; 0.81 video-level). F2O-derived features (gesture frequency, duration, and transitions) predicted postoperative outcomes with accuracy comparable to human annotations (0.79 vs. 0.75; overlapping 95% CI). Across 25 shared features, effect size directions were concordant with small differences (~ 0.07), and strong correlation (r = 0.96, p < 1e-14). F2O also captured key patterns linked to erectile function recovery, including prolonged tissue peeling and reduced energy use. By enabling automatic interpretable assessment, F2O establishes a foundation for data-driven surgical feedback and prospective clinical decision support.

Recently, research on predicting match outcomes in esports has been actively conducted, but much of it is based on match log data and statistical information. This research targets the FPS game VALORANT, which requires complex strategies, and aims to build a round outcome prediction model by analyzing minimap information in match footage. Specifically, based on the video recognition model TimeSformer, we attempt to improve prediction accuracy by incorporating detailed tactical features extracted from minimap information, such as character position information and other in-game events. This paper reports preliminary results showing that a model trained on a dataset augmented with such tactical event labels achieved approximately 81% prediction accuracy, especially from the middle phases of a round onward, significantly outperforming a model trained on a dataset with the minimap information itself. This suggests that leveraging tactical features from match footage is highly effective for predicting round outcomes in VALORANT.

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP, they often lack structured reasoning capabilities critical for high-stakes decision support. We present a unified, multi-task learning framework that aligns autoregres-sive LLMs with clinical reasoning for outcome prediction on the MSK-CHORD dataset. Our models are trained to jointly perform binary survival classification, continuous survival time regression, and natural language rationale generation. We evaluate three alignment strategies: (1) standard supervised fine-tuning (SFT), (2) SFT with Chain-of-Thought (CoT) prompting to elicit step-by-step reasoning, and (3) Group Relative Policy Optimization (GRPO), a reinforcement learning method that aligns model outputs to expert-derived reasoning trajectories. Experiments with LLaMa3-8B and Med42-8B backbones demonstrate that CoT prompting improves F1 by +6.0 and reduces MAE by 12%, while GRPO achieves state-of-the-art interpretability and predictive performance across BLEU, ROUGE, and BERTScore. We further show that existing biomedical LLMs often fail to produce valid reasoning traces due to architectural constraints. Our findings underscore the importance of reasoning-aware alignment in multi-task clinical modeling and set a new benchmark for interpretable, trustworthy LLMs in precision oncology.

Clinical notes contain rich patient information, such as diagnoses or medications, making them valuable for patient representation learning. Recent advances in large language models have further improved the ability to extract meaningful representations from clinical texts. However, clinical notes are often missing. For example, in our analysis of the MIMIC-IV dataset, 24.5% of patients have no available discharge summaries. In such cases, representations can be learned from other modalities such as structured data, chest X-rays, or radiology reports. Yet the availability of these modalities is influenced by clinical decision-making and varies across patients, resulting in modality missing-not-at-random (MMNAR) patterns. We propose a causal representation learning framework that leverages observed data and informative missingness in multimodal clinical records. It consists of: (1) an MMNAR-aware modality fusion component that integrates structured data, imaging, and text while conditioning on missingness patterns to capture patient health and clinician-driven assignment; (2) a modality reconstruction component with contrastive learning to ensure semantic sufficiency in representation learning; and (3) a multitask outcome prediction model with a rectifier that corrects for residual bias from specific modality observation patterns. Comprehensive evaluations across MIMIC-IV and eICU show consistent gains over the strongest baselines, achieving up to 13.8% AUC improvement for hospital readmission and 13.1% for ICU admission.

Atrial fibrillation (AF) is a prevalent cardiac arrhythmia often treated with catheter ablation procedures, but procedural outcomes are highly variable. Evaluating and improving ablation efficacy is challenging due to the complex interaction between patient-specific tissue and procedural factors. This paper asks two questions: Can AF recurrence be predicted by simulating the effects of procedural parameters? How should we ablate to reduce AF recurrence? We propose SOFA (Simulating and Optimizing Atrial Fibrillation Ablation), a novel deep-learning framework that addresses these questions. SOFA first simulates the outcome of an ablation strategy by generating a post-ablation image depicting scar formation, conditioned on a patient's pre-ablation LGE-MRI and the specific procedural parameters used (e.g., ablation locations, duration, temperature, power, and force). During this simulation, it predicts AF recurrence risk. Critically, SOFA then introduces an optimization scheme that refines these procedural parameters to minimize the predicted risk. Our method leverages a multi-modal, multi-view generator that processes 2.5D representations of the atrium. Quantitative evaluations show that SOFA accurately synthesizes post-ablation images and that our optimization scheme leads to a 22.18\% reduction in the model-predicted recurrence risk. To the best of our knowledge, SOFA is the first framework to integrate the simulation of procedural effects, recurrence prediction, and parameter optimization, offering a novel tool for personalizing AF ablation.

--Predictive Business Process Monitoring (PBPM) aims to forecast future outcomes of ongoing business processes. However, existing methods often lack flexibility to handle real-world challenges such as simultaneous events, class imbalance, and multi-level attributes. While prior work has explored static encoding schemes and fixed LSTM architectures, they struggle to support adaptive representations and generalize across heterogeneous datasets. T o address these limitations, we propose a suite of dynamic LSTM HyperModels that integrate two-level hierarchical encoding for event and sequence attributes, character-based decomposition of event labels, and novel pseudo-embedding techniques for durations and attribute correlations. We further introduce specialized LSTM variants for simultaneous event modeling, leveraging multidimensional embeddings and time-difference flag augmentation. Experimental validation on four public and real-world datasets demonstrates up to 100% accuracy on balanced datasets and F1 scores exceeding 86% on imbalanced ones. Our approach advances PBPM by offering modular and interpretable models better suited for deployment in complex settings. Beyond PBPM, it contributes to the broader AI community by improving temporal outcome prediction, supporting data heterogeneity, and promoting explainable process intelligence frameworks. Impact Statement --Business processes underpin daily operations across healthcare, finance, public services, and logistics. Predicting the outcome of ongoing processes--such as whether a loan will be approved or a shipment delayed--can save time, reduce costs, and improve service. Our work introduces adaptive, interpretable models that overcome these hurdles, making accurate predictions in more realistic settings.

Predicting soccer match outcomes is a challenging task due to the inherently unpredictable nature of the game and the numerous dynamic factors influencing results. While it conventionally relies on meticulous feature engineering, deep learning techniques have recently shown a great promise in learning effective player and team representations directly for soccer outcome prediction. However, existing methods often overlook the heterogeneous nature of interactions among players and teams, which is crucial for accurately modeling match dynamics. To address this gap, we propose HIGFormer (Heterogeneous Interaction Graph Transformer), a novel graph-augmented transformer-based deep learning model for soccer outcome prediction. HIGFormer introduces a multi-level interaction framework that captures both fine-grained player dynamics and high-level team interactions. Specifically, it comprises (1) a Player Interaction Network, which encodes player performance through heterogeneous interaction graphs, combining local graph convolutions with a global graph-augmented transformer; (2) a Team Interaction Network, which constructs interaction graphs from a team-to-team perspective to model historical match relationships; and (3) a Match Comparison Transformer, which jointly analyzes both team and player-level information to predict match outcomes. Extensive experiments on the WyScout Open Access Dataset, a large-scale real-world soccer dataset, demonstrate that HIGFormer significantly outperforms existing methods in prediction accuracy. Furthermore, we provide valuable insights into leveraging our model for player performance evaluation, offering a new perspective on talent scouting and team strategy analysis.