Text-conditioned molecular generation aims to translate natural-language descriptions into chemical structures, enabling scientists to specify functional groups, scaffolds, and physicochemical constraints without handcrafted rules. Diffusion-based models, particularly latent diffusion models (LDMs), have recently shown promise by performing stochastic search in a continuous latent space that compactly captures molecular semantics. Yet existing methods rely on one-shot conditioning, where the entire prompt is encoded once and applied throughout diffusion, making it hard to satisfy all the requirements in the prompt. We discuss three outstanding challenges of one-shot conditioning generation, including the poor interpretability of the generated components, the failure to generate all substructures, and the overambition in considering all requirements simultaneously. We then propose three principles to address those challenges, motivated by which we propose Chain-of-Generation (CoG), a training-free multi-stage latent diffusion framework. CoG decomposes each prompt into curriculum-ordered semantic segments and progressively incorporates them as intermediate goals, guiding the denoising trajectory toward molecules that satisfy increasingly rich linguistic constraints. To reinforce semantic guidance, we further introduce a post-alignment learning phase that strengthens the correspondence between textual and molecular latent spaces. Extensive experiments on benchmark and real-world tasks demonstrate that CoG yields higher semantic alignment, diversity, and controllability than one-shot baselines, producing molecules that more faithfully reflect complex, compositional prompts while offering transparent insight into the generation process.

People can learn a new visual class from just one example, yet machine learning algorithms typically require hundreds or thousands of examples to tackle the same problems. Here we present a Hierarchical Bayesian model based on compositionality and causality that can learn a wide range of natural (although simple) visual concepts, generalizing in human-like ways from just one image. We evaluated performance on a challenging one-shot classification task, where our model achieved a human-level error rate while substantially outperforming two deep learning models. We also used a visual Turing test" to show that our model produces human-like performance on other conceptual tasks, including generating new examples and parsing."

Despite recent advances in large language models (LLMs), most QA benchmarks are still confined to single-paragraph or single-document settings, failing to capture the complexity of real-world information-seeking tasks. Practical QA often requires multi-hop reasoning over information distributed across multiple documents, modalities, and structural formats. Although prior datasets made progress in this area, they rely heavily on Wikipedia-based content and unimodal plain text, with shallow reasoning paths that typically produce brief phrase-level or single-sentence answers, thus limiting their realism and generalizability. We propose DocHop-QA, a large-scale benchmark comprising 11,379 QA instances for multimodal, multi-document, multi-hop question answering. Constructed from publicly available scientific documents sourced from PubMed, DocHop-QA is domain-agnostic and incorporates diverse information formats, including textual passages, tables, and structural layout cues. Unlike existing datasets, DocHop-QA does not rely on explicitly hyper-linked documents; instead, it supports open-ended reasoning through semantic similarity and layout-aware evidence synthesis. To scale realistic QA construction, we designed an LLM-driven pipeline grounded in 11 high-frequency scientific question concepts. We evaluated DocHop-QA through four tasks spanning structured index prediction, generative answering, and multimodal integration, reflecting both discriminative and generative paradigms. These tasks demonstrate DocHop-QA's capacity to support complex, multi-modal reasoning across multiple documents.

Humans can effortlessly draw new categories from a single exemplar, a feat that has long posed a challenge for generative models. However, this gap has started to close with recent advances in diffusion models. This one-shot drawing task requires powerful inductive biases that have not been systematically investigated. Here, we study how different inductive biases shape the latent space of Latent Diffusion Models (LDMs). Along with standard LDM regularizers (KL and vector quantization), we explore supervised regularizations (including classification and prototype-based representation) and contrastive inductive biases (using SimCLR and redundancy reduction objectives).

Extracting key concepts and their relationships from course information and materials facilitates the provision of visualizations and recommendations for learners who need to select the right courses to take from a large number of courses. However, identifying and extracting themes manually is labor-intensive and time-consuming. Previous machine learning-based methods to extract relevant concepts from courses heavily rely on detailed course materials, which necessitates labor-intensive preparation of course materials. This paper investigates the potential of LLMs such as GPT in automatically generating course concepts and their relations. Specifically, we design a suite of prompts and provide GPT with the course information with different levels of detail, thereby generating high-quality course concepts and identifying their relations. Furthermore, we comprehensively evaluate the quality of the generated concepts and relationships through extensive experiments. Our results demonstrate the viability of LLMs as a tool for supporting educational content selection and delivery.

Large Language Models (LLMs) have recently revolutionized the NLP field, while they still fall short in some specific down-stream tasks. In the work, we focus on utilizing LLMs to perform machine translation, where we observe that two patterns of errors frequently occur and drastically affect the translation quality: language mismatch and repetition. The work sets out to explore the potential for mitigating these two issues by leveraging model editing methods, e.g., by locating Feed-Forward Network (FFN) neurons or something that are responsible for the errors and deactivating them in the inference time. We find that directly applying such methods either limited effect on the targeted errors or has significant negative side-effect on the general translation quality, indicating that the located components may also be crucial for ensuring machine translation with LLMs on the rails. To this end, we propose to refine the located components by fetching the intersection of the locating results under different language settings, filtering out the aforementioned information that is irrelevant to targeted errors. The experiment results empirically demonstrate that our methods can effectively reduce the language mismatch and repetition ratios and meanwhile enhance or keep the general translation quality in most cases.

Large language models (LLMs) have grown significantly in scale, leading to a critical need for efficient model pruning techniques. Existing post-training pruning techniques primarily focus on measuring weight importance on converged dense models to determine salient weights to retain. However, they often overlook the changes in weight importance during the pruning process, which can lead to performance degradation in the pruned models. To address this issue, we present LLM-Barber (Block-Aware Rebuilder for Sparsity Mask in One-Shot), a novel one-shot pruning framework that rebuilds the sparsity mask of pruned models without any retraining or weight reconstruction. LLM-Barber incorporates block-aware error optimization across Self-Attention and MLP blocks, ensuring global performance optimization. Inspired by the recent discovery of prominent outliers in LLMs, LLM-Barber introduces an innovative pruning metric that identifies weight importance using weights multiplied by gradients. Our experiments show that LLM-Barber can efficiently prune models like LLaMA and OPT families with 7B to 13B parameters on a single A100 GPU in just 30 minutes, achieving state-of-the-art results in both perplexity and zero-shot performance across various language benchmarks. Code is available at https://github.com/YupengSu/LLM-Barber.

Ensuring the resilience of Large Language Models (LLMs) against malicious exploitation is paramount, with recent focus on mitigating offensive responses. Yet, the understanding of cant or dark jargon remains unexplored. This paper introduces a domain-specific Cant dataset and CantCounter evaluation framework, employing Fine-Tuning, Co-Tuning, Data-Diffusion, and Data-Analysis stages. Experiments reveal LLMs, including ChatGPT, are susceptible to cant bypassing filters, with varying recognition accuracy influenced by question types, setups, and prompt clues. Updated models exhibit higher acceptance rates for cant queries. Moreover, LLM reactions differ across domains, e.g., reluctance to engage in racism versus LGBT topics. These findings underscore LLMs' understanding of cant and reflect training data characteristics and vendor approaches to sensitive topics. Additionally, we assess LLMs' ability to demonstrate reasoning capabilities. Access to our datasets and code is available at https://github.com/cistineup/CantCounter.

In-context learning (ICL) is a powerful paradigm emerged from large language models (LLMs). Despite its promises, ICL performance is known to be highly sensitive to input examples. In this work, we use $\textit{in-context influences}$ to analyze few-shot ICL performance directly from the in-context examples. Our proposed influence-based example selection method can identify both positive and negative examples, outperforming several baselines when evaluated on 9 SuperGLUE tasks. Our analysis uncovers up to a $16.3\%$ performance gap between using the most negative in-context examples compared to the most positive. In a case study, we apply our influence-based framework to quantify the phenomena of recency bias in example ordering for few-shot ICL.