US psychiatrist and neurologist Karl Deisseroth and his German colleagues Peter Hegemann and Georg Nagel have been awarded this year's Nobel Prize in Physiology or Medicine for their work in the field of optogenetics. Their research has helped scientists learn more about the workings of the brain, to better understand how the human mind works. The Nobel Committee, external praised the trio for laying the foundation of a new era in neuroscience and revealing the neural circuits behind specific memories, feelings, and behaviours relevant for neurological and psychiatric disorders. In clinical medicine, researchers are using the method to try to restore sight in people with visual impairment . Optogenetics has fundamentally altered our understanding of the brain, the Nobel Assembly said.

David Baker spoke with WIRED en Español about where biological design is headed next and the great potential and risks of taking biology outside the bounds of the natural world. David Baker, a pioneer of protein design, is using AI to go where nature hasn't. The natural world as we know it represents only a fraction of what might exist. Based on this idea, AI BioDesign was born: a scientific project that combines artificial intelligence and large-scale laboratory experiments to design and test new molecules and biological functions that are not found in nature but are physically and chemically possible. In doing so, the researchers are aiming to create databases, models, and tools that could serve as "seeds" for developing the medicines and technologies of the future.

Every year, the prizes recognize the weirdest research that often raises some very serious scientific questions. Achievements that first make people laugh and then make them think. That's the motto of the Ig Nobel Prizes, an annual competition that--parodying the Nobel Prizes--recognizes some of the world's most unusual scientific studies. The organization Improbable Research has been hosting the event since 1991 with the aim of showing that science also has a humorous side in its quest to meaningfully answer questions about the world. This year the ceremony was held in Zurich, Switzerland, and recognized 10 research projects ranging from an attempt to scientifically define what a kiss is to an experiment that used buried underwear to assess soil health.

Things to Do in L.A. Tap to enable a layout that focuses on the article. Omar Yaghi, professor at the University of California, Berkeley, speaks during a media conference in Brussels, Oct. 8, 2025, after being one of three scientists awarded the Nobel Prize in chemistry. This is read by an automated voice. Please report any issues or inconsistencies here . See more from the L.A. Times in Google Search.

Nancy Guthrie sheriff's appalling past revealed: Beat handcuffed suspect so badly he needed intensive care, used VILE language about woman and lied in sworn statement Vance grounded at White House as Iran peace talks in turmoil and Trump declares: 'I expect to be bombing' New'Hollywood dose' pill: A-listers hooked on'youth elixir' that dermatologists say is anti-ageing, shrinks pores, smooths wrinkles... and even banishes rosacea Days after we got engaged, the love of my life told me he'd killed a man and buried him in a bog. I reported him to police... but then I made this irreversible mistake Ark of the Covenant's final resting place pinpointed by archaeologists as fresh search begins Ritzy Bay Area town torn apart after teacher's daughter, 16, crashed car while speeding and killed four friends... then posted a TikTok video that poured fuel on the flames Jordon Hudson extends her control over Bill Belichick's empire with secret move that is set to leave his family and friends furious Two CIA officers killed in Mexico when their car skidded off ravine and exploded after meeting about bust of'largest ever drug lab' Life-threatening cantaloupe recall in four states upgraded to FDA's highest risk level... 'reasonable probability of death' AMANDA PLATELL: Why Sarah Ferguson - with the ghost of Princess Diana at her side - is ready to sensationally blow up the Royal Family. She knows ALL their secrets... Trump confronts Xi as US forces seize Chinese ship carrying mysterious'gift' to Iran Team USA Olympics star Noah Lyles slammed for'horrible' reaction to his wife's wedding dress reveal In honour of the Queen's (purple!) reign: Kate mirrors late monarch's colourful wardrobe and wears her pearl earrings and necklace How to lose weight when perimenopause sabotages your metabolism: I'm a trainer but when I hit 46, I piled on the pounds overnight. The new'posh' drug that's easier to order than Uber Eats - and why all my middle-class friends have ditched booze and cocaine for it: JANA HOCKING Fury as murderer marries pen pal behind bars... as teenage victim's mom says: 'I'm serving a life sentence without my son' Autistic woman, 24, worked hard to build independent life for herself... now she's PARALYZED thanks to selfishness of stranger Chilling warning from Nobel physicist as date is set for humanity's final destruction The winner of the Nobel Prize in Physics has issued a stark warning to humanity, saying it could face an existential catastrophe within roughly 35 years. David Gross, who shared the 2004 Nobel Prize in Physics, warned that'due to the danger of nuclear war,' humankind may have just a little more than three decades left.

US shutdown ends: What happens next? New Epstein emails: What do they say about Trump? Last month, tech billionaire Elon Musk launched Grokipedia, an AI-powered platform, to rival online encyclopedia Wikipedia. "Grokipedia will exceed Wikipedia by several orders of magnitude in breadth, depth and accuracy," Musk posted on X the day after his site went live on October 27. Grokipedia will exceed Wikipedia by several orders of magnitude in breadth, depth and accuracy https://t.co/Nt4M6vqEZu

In February 1953, two men walked into a pub in Cambridge and announced they had found the secret of life. It was not an idle boast. One was James Watson, an American biologist from the Cavendish laboratory; the other was his British research partner, Francis Crick. The full Promethean power of their achievement would slowly emerge over decades of research by fellow geneticists. It also opened a Pandora's Box of controversial scientific and ethical issues - including human cloning, designer babies and Frankenstein foods.

Large language models (LLMs) have achieved impressive advancements across numerous disciplines, yet the critical issue of knowledge conflicts, a major source of hallucinations, has rarely been studied. While a few research explored the conflicts between the inherent knowledge of LLMs and the retrieved contextual knowledge, a comprehensive assessment of knowledge conflict in LLMs is still missing.

Scientist Who Was Offline'Living His Best Life' Stunned by Nobel Prize Win Fred Ramsdell was on vacation in the Montana wilderness when he and two colleagues received the honor for their breakthroughs in immunology. When Fred Ramsdell, 64, was named a Nobel Prize winner earlier this week, he was deep in the Wyoming mountains, blissfully offline and surrounded by fresh snow. The next day, as he was wrapping up a three-week backpacking trip with his wife, her phone began to light up with hundreds of messages about the good news: Ramsdell, along with Mary E. Brunkow and Shimon Sakaguchi, had won the 2025 Nobel Prize in Physiology or Medicine for their discoveries that reshaped immunology . Ramsdell tells WIRED he was completely unaware that the Nobel Prizes were being announced, let alone that the Nobel committee was trying to get in touch with him. Sonoma Biotherapeutics, the biotechnology firm he co-founded, told reporters that Ramsdell was "was living his best life and was off the grid on a preplanned hiking trip."