This ScienceLives article was provided to LiveScience in partnership with the National Science Foundation. Nancy J. Nersessian's research is driven by the question "How do scientists think?" Nersessian's research focuses on how the cognitive and learning practices of scientists and engineers lead to creative and innovative outcomes. She is a Regents' Professor of Cognitive Science at the Georgia Institute of Technology with joint appointments in the Ivan Allen College of Liberal Arts School of Public Policy and the College of Computing School of Interactive Computing. Her research supports the insight that scientists think not only with ideas, but also with the artifacts they create to investigate nature.