A promising way to extract computational principles from these large datasets is to train data-constrained recurrent neural networks (dRNNs).

We study online transfer reinforcement learning (RL) in episodic Markov decision processes, where experience from related source tasks is available during learning on a target task. A fundamental difficulty is that task similarity is typically defined in terms of rewards or transitions, whereas online RL algorithms operate on Bellman regression targets. As a result, naively reusing source Bellman updates introduces systematic bias and invalidates regret guarantees. We identify one-step Bellman alignment as the correct abstraction for transfer in online RL and propose re-weighted targeting (RWT), an operator-level correction that retargets continuation values and compensates for transition mismatch via a change of measure. RWT reduces task mismatch to a fixed one-step correction and enables statistically sound reuse of source data. This alignment yields a two-stage RWT $Q$-learning framework that separates variance reduction from bias correction. Under RKHS function approximation, we establish regret bounds that scale with the complexity of the task shift rather than the target MDP. Empirical results in both tabular and neural network settings demonstrate consistent improvements over single-task learning and naïve pooling, highlighting Bellman alignment as a model-agnostic transfer principle for online RL.

Imbalanced classification, where one class is observed far less frequently than the other, often causes standard training procedures to prioritize the majority class and perform poorly on rare but important cases. A classic and widely used remedy is to augment the minority class with synthetic examples, but two basic questions remain under-resolved: when does synthetic augmentation actually help, and how many synthetic samples should be generated? We develop a unified statistical framework for synthetic augmentation in imbalanced learning, studying models trained on imbalanced data augmented with synthetic minority samples and evaluated under the balanced population risk. Our theory shows that synthetic data is not always beneficial. In a ``local symmetry" regime, imbalance is not the dominant source of error near the balanced optimum, so adding synthetic samples cannot improve learning rates and can even degrade performance by amplifying generator mismatch. When augmentation can help (a ``local asymmetry" regime), the optimal synthetic size depends on generator accuracy and on whether the generator's residual mismatch is directionally aligned with the intrinsic majority-minority shift. This structure can make the best synthetic size deviate from naive full balancing, sometimes by a small refinement and sometimes substantially when generator bias is systematic. Practically, we recommend Validation-Tuned Synthetic Size (VTSS): select the synthetic size by minimizing balanced validation loss over a range centered near the fully balanced baseline, while allowing meaningful departures when the data indicate them. Simulations and a real sepsis prediction study support the theory and illustrate when synthetic augmentation helps, when it cannot, and how to tune its quantity effectively.

We study a linear observation model with an unknown permutation called \textit{permuted/shuffled linear regression}, where responses and covariates are mismatched and the permutation forms a discrete, factorial-size parameter. The permutation is a key component of the data-generating process, yet its statistical investigation remains challenging due to its discrete nature. We develop a general statistical inference framework on the permutation and regression coefficients. First, we introduce a localization step that reduces the permutation space to a small candidate set building on recent advances in the repro samples method, whose miscoverage decays polynomially with the number of Monte Carlo samples. Then, based on this localized set, we provide statistical inference procedures: a conditional Monte Carlo test of permutation structures with valid finite-sample Type-I error control. We also develop coefficient inference that remains valid under alignment uncertainty of permutations. For computational purposes, we develop a linear assignment problem computable in polynomial time and demonstrate that, with high probability, the solution is equivalent to that of the conventional least squares with large computational cost. Extensions to partially permuted designs and ridge regularization are further discussed. Extensive simulations and an application to air-quality data corroborate finite-sample validity, strong power to detect mismatches, and practical scalability.

Fitted Q-evaluation (FQE) is a central method for off-policy evaluation in reinforcement learning, but it generally requires Bellman completeness: that the hypothesis class is closed under the evaluation Bellman operator. This requirement is challenging because enlarging the hypothesis class can worsen completeness. We show that the need for this assumption stems from a fundamental norm mismatch: the Bellman operator is gamma-contractive under the stationary distribution of the target policy, whereas FQE minimizes Bellman error under the behavior distribution. We propose a simple fix: reweight each regression step using an estimate of the stationary density ratio, thereby aligning FQE with the norm in which the Bellman operator contracts. This enables strong evaluation guarantees in the absence of realizability or Bellman completeness, avoiding the geometric error blow-up of standard FQE in this setting while maintaining the practicality of regression-based evaluation.

Reinforcement learning for large language models (LLMs) faces a fundamental tension: high-throughput inference engines and numerically-precise training systems produce different probability distributions from the same parameters, creating a training-inference mismatch. We prove this mismatch has an asymmetric effect: the bound on log-probability mismatch scales as $(1-p)$ where $p$ is the token probability. For high-probability tokens, this bound vanishes, contributing negligibly to sequence-level mismatch. For low-probability tokens in the tail, the bound remains large, and moreover, when sampled, these tokens exhibit systematically biased mismatches that accumulate over sequences, destabilizing gradient estimation. Rather than applying post-hoc corrections, we propose constraining the RL objective to a dynamically-pruned ``safe'' vocabulary that excludes the extreme tail. By pruning such tokens, we trade large, systematically biased mismatches for a small, bounded optimization bias. Empirically, our method achieves stable training; theoretically, we bound the optimization bias introduced by vocabulary pruning.

Advances in optical and electrophysiological recording technologies have made it possible to record the dynamics of thousands of neurons, opening up new possibilities for interpreting and controlling large neural populations in behaving animals. A promising way to extract computational principles from these large datasets is to train data-constrained recurrent neural networks (dRNNs). Performing this training in real-time could open doors for research techniques and medical applications to model and control interventions at single-cell resolution and drive desired forms of animal behavior. However, existing training algorithms for dRNNs are inefficient and have limited scalability, making it a challenge to analyze large neural recordings even in offline scenarios. To address these issues, we introduce a training method termed Convex Optimization of Recurrent Neural Networks (CORNN). In studies of simulated recordings, CORNN attained training speeds $\sim$100-fold faster than traditional optimization approaches while maintaining or enhancing modeling accuracy. We further validated CORNN on simulations with thousands of cells that performed simple computations such as those of a 3-bit flip-flop or the execution of a timed response. Finally, we showed that CORNN can robustly reproduce network dynamics and underlying attractor structures despite mismatches between generator and inference models, severe subsampling of observed neurons, or mismatches in neural time-scales. Overall, by training dRNNs with millions of parameters in subminute processing times on a standard computer, CORNN constitutes a first step towards real-time network reproduction constrained on large-scale neural recordings and a powerful computational tool for advancing the understanding of neural computation.

The analysis and use of egocentric videos for robotics tasks is made challenging by occlusion and the visual mismatch between the human hand and a robot end-effector. Past work views the human hand as a nuisance and removes it from the scene. However, the hand also provides a valuable signal for learning. In this work, we propose to extract a factored representation of the scene that separates the agent (human hand) and the environment.

In real word applications, data generating process for training a machine learning model often differs from what the model encounters in the test stage. Understanding how and whether machine learning models generalize under such distributional shifts have been a theoretical challenge. Here, we study generalization in kernel regression when the training and test distributions are different using methods from statistical physics. Using the replica method, we derive an analytical formula for the out-of-distribution generalization error applicable to any kernel and real datasets. We identify an overlap matrix that quantifies the mismatch between distributions for a given kernel as a key determinant of generalization performance under distribution shift. Using our analytical expressions we elucidate various generalization phenomena including possible improvement in generalization when there is a mismatch. We develop procedures for optimizing training and test distributions for a given data budget to find best and worst case generalizations under the shift.