Alzheimer's disease (AD), the most common cause of dementia and impaired cognitive function, still has no effective treatment, according to researchers. So research is centered on identifying AD biomarkers and targets. Now, scientists at King Abdullah University of Science and Technology in Saudi Arabia have created a computational method that identifies AD biomarkers and targets. It combines multiple "hub gene" ranking methods and "feature selection" methods with machine learning and deep learning.To identify hub genes and gene subsets, the researchers used three AD gene expression datasets using six ranking algorithms and two feature-selection methods. The researchers then created machine learning and deep learning models to identify the gene subset that best distinguished Alzheimer's disease samples from healthy controls.

SingularityNET development and blockchain teams have partnered with MLabs, experts in Plutus development for Cardano, to create the AGIX-ADA staking contracts. The contracts are currently under evaluation in testnet and will soon be audited externally. The final stage of development will be creating the staking portal on the SingularityDAO v2 Dapp. The SingularityDAO v2 Dapp is gearing up for launch in Q3, and the staking portal will be launched shortly after that, approximately mid-Q3. The Loyalty Rewards wallet was created to demonstrate the gratitude of SingularityNET to the Phase One token holders for supporting the Phase Two initiative; as well as an opportunity to incentivize and reward community growth through new token holders on the Cardano blockchain. The technical backend portal has been designed and is under evaluation on testnet, and the team is also actively working to integrate more wallets. The portal is expected to be ready for community launch in Q3, and further details on the program will be coming shortly. We look forward to community feedback and discussion as we work with the community to design an optimal system.

This is just one of a series of posts giving our valued community a review of our 2021 achievements… and a small peek at what comes next! This Roadmap End-of-Year Review Series will be followed up next year with an in-depth series on the Roadmap plans for 2022 in January/February. Don't miss the rest of this series! Mindplex is developing a media platform and AI accessories to decentralize and democratize media. The Mindplex Content Factory will match content creators and content consumers based on an AI-driven reputation system, combined with tokenomics, to help the platform to be more decentralized, community-led, and merit-based.