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 longitudinal study


SnappyMeal: Design and Longitudinal Evaluation of a Multimodal AI Food Logging Application

Bakar, Liam, Englhardt, Zachary, Srinivas, Vidya, Narayanswamy, Girish, Nissanka, Dilini, Patel, Shwetak, Iyer, Vikram

arXiv.org Artificial Intelligence

Food logging, both self-directed and prescribed, plays a critical role in uncovering correlations between diet, medical, fitness, and health outcomes. Through conversations with nutritional experts and individuals who practice dietary tracking, we find current logging methods, such as handwritten and app-based journaling, are inflexible and result in low adherence and potentially inaccurate nutritional summaries. These findings, corroborated by prior literature, emphasize the urgent need for improved food logging methods. In response, we propose SnappyMeal, an AI-powered dietary tracking system that leverages multimodal inputs to enable users to more flexibly log their food intake. SnappyMeal introduces goal-dependent follow-up questions to intelligently seek missing context from the user and information retrieval from user grocery receipts and nutritional databases to improve accuracy. We evaluate SnappyMeal through publicly available nutrition benchmarks and a multi-user, 3-week, in-the-wild deployment capturing over 500 logged food instances. Users strongly praised the multiple available input methods and reported a strong perceived accuracy. These insights suggest that multimodal AI systems can be leveraged to significantly improve dietary tracking flexibility and context-awareness, laying the groundwork for a new class of intelligent self-tracking applications.


Help the machine to help you: an evaluation in the wild of egocentric data cleaning via skeptical learning

Bontempelli, Andrea, Busso, Matteo, Malcotti, Leonardo Javier, Giunchiglia, Fausto

arXiv.org Artificial Intelligence

Any digital personal assistant, whether used to support task performance, answer questions, or manage work and daily life--including fitness schedules--requires high-quality annotations to function properly. However, user annotations, whether actively produced or inferred from context (e.g., data from smartphone sensors), are often subject to errors and noise. Previous research on Skeptical Learning ( skel) addressed the issue of noisy labels by comparing offline active annotations with passive data, allowing for an evaluation of annotation accuracy. However, this evaluation did not include confirmation from end-users, the best judges of their own context. In this study, we evaluate skel's performance in real-world conditions with actual users who can refine the input labels based on their current perspectives and needs. The study involves university students using the iLog mobile application on their devices over a period of four weeks. The results highlight the challenges of finding the right balance between user effort and data quality, as well as the potential benefits of using skel, which include reduced annotation effort and improved quality of collected data.


LinGuinE: Longitudinal Guidance Estimation for Volumetric Lung Tumour Segmentation

Garibli, Nadine, Patwari, Mayank, Csiba, Bence, Wei, Yi, Sidiropoulos, Kostas

arXiv.org Artificial Intelligence

Segmentation of lung gross tumour volumes is an important first step in radiotherapy and surgical intervention, and is starting to play a role in assessing chemotherapy response. Response to a drug is measured by tracking the tumour volumes over a series of CT scans over a time period i.e. a longitudinal study. However, there currently exist few solutions for automated or semi-automated longitudinal tumour segmentation. This paper introduces LinGuinE, an automated method to segment a longitudinal series of lung tumours. A radiologist must provide an initial input, indicating the location of the tumour in a CT scan at an arbitrary time point. LinGuinE samples points inside this tumour and propagates them to another time point using rigid registration. A click validity classifier selects points which still fall within the tumour; these are used to automatically create a segmentation in the new time point. We test LinGuinE on a dataset acquired from a phase 3 clinical trial for lung tumours and the publicly available 4-D lung CBCT dataset. We find that LinGuinE improves the Dice on both test sets by over 20% (p< 0.05) across 63 longitudinal studies. We show that any time point can be used as a starting point, conduct ablation experiments, and find that our LinGuinE setup yields the best results on both test datasets.


Imputation Matters: A Deeper Look into an Overlooked Step in Longitudinal Health and Behavior Sensing Research

Choube, Akshat, Majethia, Rahul, Bhattacharya, Sohini, Swain, Vedant Das, Li, Jiachen, Mishra, Varun

arXiv.org Artificial Intelligence

Longitudinal passive sensing studies for health and behavior outcomes often have missing and incomplete data. Handling missing data effectively is thus a critical data processing and modeling step. Our formative interviews with researchers working in longitudinal health and behavior passive sensing revealed a recurring theme: most researchers consider imputation a low-priority step in their analysis and inference pipeline, opting to use simple and off-the-shelf imputation strategies without comprehensively evaluating its impact on study outcomes. Through this paper, we call attention to the importance of imputation. Using publicly available passive sensing datasets for depression, we show that prioritizing imputation can significantly impact the study outcomes -- with our proposed imputation strategies resulting in up to 31% improvement in AUROC to predict depression over the original imputation strategy. We conclude by discussing the challenges and opportunities with effective imputation in longitudinal sensing studies.


Sampling-guided Heterogeneous Graph Neural Network with Temporal Smoothing for Scalable Longitudinal Data Imputation

Zhang, Zhaoyang, Chen, Ziqi, Liu, Qiao, Xie, Jinhan, Zhu, Hongtu

arXiv.org Artificial Intelligence

In this paper, we propose a novel framework, the Sampling-guided Heterogeneous Graph Neural Network (SHT-GNN), to effectively tackle the challenge of missing data imputation in longitudinal studies. Unlike traditional methods, which often require extensive preprocessing to handle irregular or inconsistent missing data, our approach accommodates arbitrary missing data patterns while maintaining computational efficiency. SHT-GNN models both observations and covariates as distinct node types, connecting observation nodes at successive time points through subject-specific longitudinal subnetworks, while covariate-observation interactions are represented by attributed edges within bipartite graphs. By leveraging subject-wise mini-batch sampling and a multi-layer temporal smoothing mechanism, SHT-GNN efficiently scales to large datasets, while effectively learning node representations and imputing missing data. Extensive experiments on both synthetic and real-world datasets, including the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset, demonstrate that SHT-GNN significantly outperforms existing imputation methods, even with high missing data rates. The empirical results highlight SHT-GNN's robust imputation capabilities and superior performance, particularly in the context of complex, large-scale longitudinal data.


A Longitudinal Study of Child Wellbeing Assessment via Online Interactions with a Social Robots

Abbasi, Nida Itrat, Laban, Guy, Ford, Tamsin, Jones, Peter B., Gunes, Hatice

arXiv.org Artificial Intelligence

Socially Assistive Robots are studied in different Child-Robot Interaction settings. However, logistical constraints limit accessibility, particularly affecting timely support for mental wellbeing. In this work, we have investigated whether online interactions with a robot can be used for the assessment of mental wellbeing in children. The children (N=40, 20 girls and 20 boys; 8-13 years) interacted with the Nao robot (30-45 mins) over three sessions, at least a week apart. Audio-visual recordings were collected throughout the sessions that concluded with the children answering user perception questionnaires pertaining to their anxiety towards the robot, and the robot's abilities. We divided the participants into three wellbeing clusters (low, med and high tertiles) using their responses to the Short Moods and Feelings Questionnaire (SMFQ) and further analysed how their wellbeing and their perceptions of the robot changed over the wellbeing tertiles, across sessions and across participants' gender. Our primary findings suggest that (I) online mediated-interactions with robots can be effective in assessing children's mental wellbeing over time, and (II) children's overall perception of the robot either improved or remained consistent across time. Supplementary exploratory analyses have also revealed that gender affected the children's wellbeing assessments as well as their perceptions of the robot.


Feeding the Coffee Habit: A Longitudinal Study of a Robo-Barista

Lim, Mei Yii, Robb, David A., Wilson, Bruce W., Hastie, Helen

arXiv.org Artificial Intelligence

Studying Human-Robot Interaction over time can provide insights into what really happens when a robot becomes part of people's everyday lives. "In the Wild" studies inform the design of social robots, such as for the service industry, to enable them to remain engaging and useful beyond the novelty effect and initial adoption. This paper presents an "In the Wild" experiment where we explored the evolution of interaction between users and a Robo-Barista. We show that perceived trust and prior attitudes are both important factors associated with the usefulness, adaptability and likeability of the Robo-Barista. A combination of interaction features and user attributes are used to predict user satisfaction. Qualitative insights illuminated users' Robo-Barista experience and contribute to a number of lessons learned for future long-term studies.


Comparison of different automatic solutions for resection cavity segmentation in postoperative MRI volumes including longitudinal acquisitions

Canalini, Luca, Klein, Jan, de Barros, Nuno Pedrosa, Sima, Diana Maria, Miller, Dorothea, Hahn, Horst

arXiv.org Artificial Intelligence

In this work, we compare five deep learning solutions to automatically segment the resection cavity in postoperative MRI. The proposed methods are based on the same 3D U-Net architecture. We use a dataset of postoperative MRI volumes, each including four MRI sequences and the ground truth of the corresponding resection cavity. Four solutions are trained with a different MRI sequence. Besides, a method designed with all the available sequences is also presented. Our experiments show that the method trained only with the T1 weighted contrast-enhanced MRI sequence achieves the best results, with a median DICE index of 0.81.


GLACIAL: Granger and Learning-based Causality Analysis for Longitudinal Studies

Nguyen, Minh, Ngo, Gia H., Sabuncu, Mert R.

arXiv.org Artificial Intelligence

The Granger framework is widely used for discovering causal relationships based on time-varying signals. Implementations of Granger causality (GC) are mostly developed for densely sampled timeseries data. A substantially different setting, particularly common in population health applications, is the longitudinal study design, where multiple individuals are followed and sparsely observed for a limited number of times. Longitudinal studies commonly track many variables, which are likely governed by nonlinear dynamics that might have individual-specific idiosyncrasies and exhibit both direct and indirect causes. Furthermore, real-world longitudinal data often suffer from widespread missingness. GC methods are not well-suited to handle these issues. In this paper, we intend to fill this methodological gap. We propose to marry the GC framework with a machine learning based prediction model. We call our approach GLACIAL, which stands for "Granger and LeArning-based CausalIty Analysis for Longitudinal studies." GLACIAL treats individuals as independent samples and uses average prediction accuracy on hold-out individuals to test for effects of causal relationships. GLACIAL employs a multi-task neural network trained with input feature dropout to efficiently learn nonlinear dynamic relationships between a large number of variables, handle missing values, and probe causal links. Extensive experiments on synthetic and real data demonstrate the utility of GLACIAL and how it can outperform competitive baselines.


Dynamic Bayesian Network Modelling of User Affect and Perceptions of a Teleoperated Robot Coach during Longitudinal Mindfulness Training

Bodala, Indu P., Gunes, Hatice

arXiv.org Artificial Intelligence

Longitudinal interaction studies with Socially Assistive Robots are crucial to ensure that the robot is relevant for long-term use and its perceptions are not prone to the novelty effect. In this paper, we present a dynamic Bayesian network (DBN) to capture the longitudinal interactions participants had with a teleoperated robot coach (RC) delivering mindfulness sessions. The DBN model is used to study complex, temporal interactions between the participants self-reported personality traits, weekly baseline wellbeing scores, session ratings, and facial AUs elicited during the sessions in a 5-week longitudinal study. DBN modelling involves learning a graphical representation that facilitates intuitive understanding of how multiple components contribute to the longitudinal changes in session ratings corresponding to the perceptions of the RC, and participants relaxation and calm levels. The learnt model captures the following within and between sessions aspects of the longitudinal interaction study: influence of the 5 personality dimensions on the facial AU states and the session ratings, influence of facial AU states on the session ratings, and the influences within the items of the session ratings. The DBN structure is learnt using first 3 time points and the obtained model is used to predict the session ratings of the last 2 time points of the 5-week longitudinal data. The predictions are quantified using subject-wise RMSE and R2 scores. We also demonstrate two applications of the model, namely, imputation of missing values in the dataset and estimation of longitudinal session ratings of a new participant with a given personality profile. The obtained DBN model thus facilitates learning of conditional dependency structure between variables in the longitudinal data and offers inferences and conceptual understanding which are not possible through other regression methodologies.