This article explores the convergence of connectionist and symbolic artificial intelligence (AI), from historical debates to contemporary advancements. Traditionally considered distinct paradigms, connectionist AI focuses on neural networks, while symbolic AI emphasizes symbolic representation and logic. Recent advancements in large language models (LLMs), exemplified by ChatGPT and GPT-4, highlight the potential of connectionist architectures in handling human language as a form of symbols. The study argues that LLM-empowered Autonomous Agents (LAAs) embody this paradigm convergence. By utilizing LLMs for text-based knowledge modeling and representation, LAAs integrate neuro-symbolic AI principles, showcasing enhanced reasoning and decision-making capabilities. Comparing LAAs with Knowledge Graphs within the neuro-symbolic AI theme highlights the unique strengths of LAAs in mimicking human-like reasoning processes, scaling effectively with large datasets, and leveraging in-context samples without explicit re-training. The research underscores promising avenues in neuro-vector-symbolic integration, instructional encoding, and implicit reasoning, aimed at further enhancing LAA capabilities. By exploring the progression of neuro-symbolic AI and proposing future research trajectories, this work advances the understanding and development of AI technologies.

Active Domain Adaptation (ADA) queries the labels of a small number of selected target samples to help adapting a model from a source domain to a target domain. The local context of queried data is important, especially when the domain gap is large. However, this has not been fully explored by existing ADA works. In this paper, we propose a Local context-aware ADA framework, named LADA, to address this issue. To select informative target samples, we devise a novel criterion based on the local inconsistency of model predictions. Since the labeling budget is usually small, fine-tuning model on only queried data can be inefficient. We progressively augment labeled target data with the confident neighbors in a class-balanced manner. Experiments validate that the proposed criterion chooses more informative target samples than existing active selection strategies. Furthermore, our full method clearly surpasses recent ADA arts on various benchmarks. Code is available at https://github.com/tsun/LADA.

The massive successes of large language models (LLMs) encourage the emerging exploration of LLM-augmented Autonomous Agents (LAAs). An LAA is able to generate actions with its core LLM and interact with environments, which facilitates the ability to resolve complex tasks by conditioning on past interactions such as observations and actions. Since the investigation of LAA is still very recent, limited explorations are available. Therefore, we provide a comprehensive comparison of LAA in terms of both agent architectures and LLM backbones. Additionally, we propose a new strategy to orchestrate multiple LAAs such that each labor LAA focuses on one type of action, i.e. BOLAA, where a controller manages the communication among multiple agents. We conduct simulations on both decision-making and multi-step reasoning environments, which comprehensively justify the capacity of LAAs. Our performance results provide quantitative suggestions for designing LAA architectures and the optimal choice of LLMs, as well as the compatibility of both. LAA extends the intelligence of LLM to sequential action executions, exhibiting superiority in interacting with environments and resolving complex tasks via collecting observations. ReAct (Yao et al., 2023a) is a recently proposed LAA method to interact with environments then consecutively generate the next action. Due to the initial investigation, LAA is rather under-explored.

The assessment of left atrial appendage (LAA) thrombogenesis has experienced major advances with the adoption of patient-specific computational fluid dynamics (CFD) simulations. Nonetheless, due to the vast computational resources and long execution times required by fluid dynamics solvers, there is an ever-growing body of work aiming to develop surrogate models of fluid flow simulations based on neural networks. The present study builds on this foundation by developing a deep learning (DL) framework capable of predicting the endothelial cell activation potential (ECAP), linked to the risk of thrombosis, solely from the patient-specific LAA geometry. To this end, we leveraged recent advancements in Geometric DL, which seamlessly extend the unparalleled potential of convolutional neural networks (CNN), to non-Euclidean data such as meshes. The model was trained with a dataset combining 202 synthetic and 54 real LAA, predicting the ECAP distributions instantaneously, with an average mean absolute error of 0.563. Moreover, the resulting framework manages to predict the anatomical features related to higher ECAP values even when trained exclusively on synthetic cases.

We propose a novel deep neural network (DNN) based approximation architecture to learn estimates of measurements. We detail an algorithm that enables training of the DNN. The DNN estimator only uses measurements, if and when they are received over a communication network. The measurements are communicated over a network as packets, at a rate unknown to the estimator. Packets may suffer drops and need retransmission. They may suffer waiting delays as they traverse a network path. Works on estimation often assume knowledge of the dynamic model of the measured system, which may not be available in practice. The DNN estimator doesn't assume knowledge of the dynamic system model or the communication network. It doesn't require a history of measurements, often used by other works. The DNN estimator results in significantly smaller average estimation error than the commonly used Time-varying Kalman Filter and the Unscented Kalman Filter, in simulations of linear and nonlinear dynamic systems. The DNN need not be trained separately for different communications network settings. It is robust to errors in estimation of network delays that occur due to imperfect time synchronization between the measurement source and the estimator. Last but not the least, our simulations shed light on the rate of updates that result in low estimation error.

In preoperative planning of left atrial appendage closure (LAAC) with CT angiography, the assessment of the appendage orifice plays a crucial role in choosing an appropriate LAAC device size and a proper C-arm angulation. However, accurate orifice detection is laborious because of the high anatomic variation of the appendage, as well as the unclear orifice position and orientation in the available views. We propose an automatic orifice detection approach performing a search on the principal medial axis of the appendage, where we present an efficient iterative algorithm to grow the axis from the appendage to the left atrium. We propose to use the axis-to-surface distance of the appendage for efficient and effective detection. To localize the necessary initial seed for growing the medial axis, we train an artificial localization agent using an actor-critic reinforcement learning approach, defining the localization as a sequential decision process. The entire detection process takes only about 8 seconds, and the variance of the detected orifice with respect to annotations from two experts is calculated to be significantly small and less than the inter-observer variance. The proposed orifice search on the medial axis of the appendage comparing only its distance from the surface provides a simple, yet robust solution for orifice detection. While being the first fully automatic approach and providing a detection error below the inter-observer difference, our method improved the detection efficiency by eighteen times compared to the existing solution, therefore, can be potentially useful for physicians.