High-stakes decision domains are increasingly exploring the potential of Large Language Models (LLMs) for complex decision-making tasks. However, LLM deployment in real-world settings presents challenges in data security, evaluation of its capabilities outside controlled environments, and accountability attribution in the event of adversarial decisions. This paper proposes a framework for responsible deployment of LLM-based decision-support systems through active human involvement. It integrates interactive collaboration between human experts and developers through multiple iterations at the pre-deployment stage to assess the uncertain samples and judge the stability of the explanation provided by post-hoc XAI techniques. Local LLM deployment within organizations and decentralized technologies, such as Blockchain and IPFS, are proposed to create immutable records of LLM activities for automated auditing to enhance security and trace back accountability. It was tested on Bert-large-uncased, Mistral, and LLaMA 2 and 3 models to assess the capability to support responsible financial decisions on business lending.

--Weather forecasting plays a vital role in disaster preparedness, agriculture, and resource management, yet current centralized forecasting systems are increasingly strained by security vulnerabilities, limited scalability, and susceptibility to single points of failure. T o address these challenges, we propose a decentralized weather forecasting framework that integrates Federated Learning (FL) with blockchain technology. FL enables collaborative model training without exposing sensitive local data, this approach enhances privacy and reduces data transfer overhead. Meanwhile, the Ethereum blockchain ensures transparent and dependable verification of model updates. T o further enhance the system's security, we introduce a reputation-based voting mechanism that assesses the trustworthiness of submitted models while utilizing the Interplanetary File System (IPFS) for efficient off-chain storage. Experimental results demonstrate that our approach not only improves forecasting accuracy but also enhances system resilience and scalability, making it a viable candidate for deployment in real-world, security-critical environments. Weather forecasting is essential for agricultural productivity, disaster preparedness, and economic stability. However, traditional forecasting methods tend to rely on centralized systems. This centralization poses significant risks, including vulnerabilities to data manipulation, privacy breaches, and single points of failure [8]. Centralized Machine Learning (ML) models, despite their high accuracy, are vulnerable to adversarial threats, such as data poisoning, where attackers introduce incorrect data to compromise forecast reliability [32]. Reliable weather forecasting systems are foundational to sectors like the insurance industry, where the integrity of environmental data directly influences risk assessment and claim processing.

The progression of Idiopathic Pulmonary Fibrosis (IPF) significantly correlates with higher patient mortality rates. Early detection of IPF progression is critical for initiating timely treatment, which can effectively slow down the advancement of the disease. However, the current clinical criteria define disease progression requiring two CT scans with a one-year interval, presenting a dilemma: a disease progression is identified only after the disease has already progressed. To this end, in this paper, we develop a novel diffusion model to accurately predict the progression of IPF by generating patient's follow-up CT scan from the initial CT scan. Specifically, from the clinical prior knowledge, we tailor improvements to the traditional diffusion model and propose a Clinically-Informed Residual Diffusion model, called CIResDiff. The key innovations of CIResDiff include 1) performing the target region pre-registration to align the lung regions of two CT scans at different time points for reducing the generation difficulty, 2) adopting the residual diffusion instead of traditional diffusion to enable the model focus more on differences (i.e., lesions) between the two CT scans rather than the largely identical anatomical content, and 3) designing the clinically-informed process based on CLIP technology to integrate lung function information which is highly relevant to diagnosis into the reverse process for assisting generation. Extensive experiments on clinical data demonstrate that our approach can outperform state-of-the-art methods and effectively predict the progression of IPF.

In this paper, we present a study of a Federated Learning (FL) system, based on the use of decentralized architectures to ensure trust and increase reliability. The system is based on the idea that the FL collaborators upload the (ciphered) model parameters on the Inter-Planetary File System (IPFS) and interact with a dedicated smart contract to track their behavior. Thank to this smart contract, the phases of parameter updates are managed efficiently, thereby strengthening data security. We have carried out an experimental study that exploits two different methods of weight aggregation, i.e., a classic averaging scheme and a federated proximal aggregation. The results confirm the feasibility of the proposal.

A nonlinear-dynamical algorithm for city planning is proposed as an Impulse Pattern Formulation (IPF) for predicting relevant parameters like health, artistic freedom, or financial developments of different social or political stakeholders over the cause of a planning process. The IPF has already shown high predictive precision at low computational cost in musical instrument simulations, brain dynamics, and human-human interactions. The social and political IPF consists of three basic equations of system state developments, self-adaptation of stakeholders, two adaptive interactions, and external impact terms suitable for respective planning situations. Typical scenarios of stakeholder interactions and developments are modeled by adjusting a set of system parameters. These include stakeholder reaction to external input, enhanced system stability through self-adaptation, stakeholder convergence due to adaptive interaction, as well as complex dynamics in terms of fixed stakeholder impacts. A workflow for implementing the algorithm in real city planning scenarios is outlined. This workflow includes machine learning of a suitable set of parameters suggesting best-practice planning to aim at the desired development of the planning process and its output.

Machine learning is increasingly used for intrusion detection in IoT networks. This paper explores the effectiveness of using individual packet features (IPF), which are attributes extracted from a single network packet, such as timing, size, and source-destination information. Through literature review and experiments, we identify the limitations of IPF, showing they can produce misleadingly high detection rates. Our findings emphasize the need for approaches that consider packet interactions for robust intrusion detection. Additionally, we demonstrate that models based on IPF often fail to generalize across datasets, compromising their reliability in diverse IoT environments.

A common network inference problem, arising from real-world data constraints, is how to infer a dynamic network from its time-aggregated adjacency matrix and time-varying marginals (i.e., row and column sums). Prior approaches to this problem have repurposed the classic iterative proportional fitting (IPF) procedure, also known as Sinkhorn's algorithm, with promising empirical results. However, the statistical foundation for using IPF has not been well understood: under what settings does IPF provide principled estimation of a dynamic network from its marginals, and how well does it estimate the network? In this work, we establish such a setting, by identifying a generative network model whose maximum likelihood estimates are recovered by IPF. Our model both reveals implicit assumptions on the use of IPF in such settings and enables new analyses, such as structure-dependent error bounds on IPF's parameter estimates. When IPF fails to converge on sparse network data, we introduce a principled algorithm that guarantees IPF converges under minimal changes to the network structure. Finally, we conduct experiments with synthetic and real-world data, which demonstrate the practical value of our theoretical and algorithmic contributions.