Way back in the summer of 2017, AI researchers at Google put out a paper called "Attention Is All You Need," in which they described a new type of neural network called a transformer. It proved to be very good at processing long sequences of data, especially text. Nine years on, transformers are the engines inside every major large language model on the market. "The entire AI industry is built on transformers," says Justin Dangel, cofounder and CEO of the AI startup Subquadratic. "They are one of the most important innovations in the history of computer science, and they've changed the world." But transformers are starting to show their age. Many of the recent advances in LLMs, such as the development of so-called reasoning models and their ability to handle large amounts of input at once, are not neat extensions of that core technology but workarounds that patch over some of its fundamental flaws. A growing number of scientists and engineers are now asking what's coming next. LLMs are not going anywhere, but the way they get built is up for grabs.

A key strength of diffusion models lies in their flexibility, since their outputs can be controlled at sampling time through guidance. However, beyond simple cases such as conditional sampling, the target distribution is often left implicit, defined only through a sampling rule or a heuristic energy function. To address this, we propose Jeffrey guidance, a principled framework that extends diffusion-model control to applications beyond what standard guidance can express. It leverages Jeffrey's rule of conditioning to update marginal distributions towards a prescribed target, preserving the conditional structure and minimally perturbing the joint distribution. We first demonstrate Jeffrey guidance by targeting a prescribed embedding distribution. With Inception embeddings as the target, this leads to substantial reductions in FID on both CIFAR-10 and FFHQ. We further apply Jeffrey guidance to fairness on CelebA-HQ, updating an unconditional diffusion model to enforce independence between attributes.

This basic formula has seen almost universal adoption across many different medical specialties.

As the development of AI-generated contents (AIGC), multi-modal Large Language Models (LLM) struggle to identify generated visual inputs from real ones. Such shortcoming causes vulnerability against visual deceptions, where the models are deceived by generated contents, and the reliability of reasoning processes is jeopardized. Therefore, facing rapidly emerging generative models and diverse data distribution, it is of vital importance to improve LLMs' generalizable reasoning to verify the authenticity of visual inputs against potential deceptions. Inspired by human cognitive processes, we discovered that LLMs exhibit tendency of over-trusting the visual inputs, while injecting skepticism could significantly improve the models visual cognitive capability against visual deceptions. Based on this discovery, we propose \textbf{Inception}, a fully reasoning-based agentic reasoning framework to conduct generalizable authenticity verification by injecting skepticism, where LLMs' reasoning logic is iteratively enhanced between External Skeptic and Internal Skeptic agents. To the best of our knowledge, this is the first fully reasoning-based framework against AIGC visual deceptions. Our approach achieved a large margin of performance improvement over the strongest existing LLM baselines and SOTA performance on AEGIS benchmark.

Early and accurate detection of the bone fracture is paramount to initiating treatment as early as possible and avoiding any delay in patient treatment and outcomes. Interpretation of X-ray image is a time consuming and error prone task, especially when resources for such interpretation are limited by lack of radiology expertise. Additionally, deep learning approaches used currently, typically suffer from misclassifications and lack interpretable explanations to clinical use. In order to overcome these challenges, we propose an automated framework of bone fracture detection using a VGG-19 model modified to our needs. It incorporates sophisticated preprocessing techniques that include Contrast Limited Adaptive Histogram Equalization (CLAHE), Otsu's thresholding, and Canny edge detection, among others, to enhance image clarity as well as to facilitate the feature extraction. Therefore, we use Grad-CAM, an Explainable AI method that can generate visual heatmaps of the model's decision making process, as a type of model interpretability, for clinicians to understand the model's decision making process. It encourages trust and helps in further clinical validation. It is deployed in a real time web application, where healthcare professionals can upload X-ray images and get the diagnostic feedback within 0.5 seconds. The performance of our modified VGG-19 model attains 99.78\% classification accuracy and AUC score of 1.00, making it exceptionally good. The framework provides a reliable, fast, and interpretable solution for bone fracture detection that reasons more efficiently for diagnoses and better patient care.

Large language models (LLMs) excel at reasoning-only tasks, but struggle when reasoning must be tightly coupled with retrieval, as in multi-hop question answering. To overcome these limitations, we introduce a prompting strategy that first decomposes a complex question into smaller steps, then dynamically constructs a database of facts using LLMs, and finally pieces these facts together to solve the question. We show how this three-stage strategy, which we call Memento, can boost the performance of existing prompting strategies across diverse settings. On the 9-step PhantomWiki benchmark, Memento doubles the performance of chain-of-thought (CoT) when all information is provided in context. On the open-domain version of 2WikiMultiHopQA, CoT-RAG with Memento improves over vanilla CoT-RAG by more than 20 F1 percentage points and over the multi-hop RAG baseline, IRCoT, by more than 13 F1 percentage points. On the challenging MuSiQue dataset, Memento improves ReAct by more than 3 F1 percentage points, demonstrating its utility in agentic settings.

Conversational agents are designed to understand dialogs and generate meaningful responses to communicate with humans. After the popularity of ChatGPT, with its surprising performance and powerful conversational ability, commercial Large Language Models (LLMs) for general NLP tasks such as GPT-4 [1], etc., sprung up and brought the generative AI as a solution to the public view. These LLMs work quite well in content generation tasks, but their deficiency in fact-and-knowledge-oriented tasks is wellestablished by now [13]. These models themselves cannot tell whether the text they generate is based on facts or made-up stories, and they cannot always follow the given data and rules strictly and sometimes even modify the data at will, also called hallucination. The reasoning that these LLMs appear to perform is also at a very shallow level.

Our brains have to do a lot of work when we watch a movie. There are plots to follow, dialogue to interpret, visuals to take in, and more. Now, scientists have created a detailed map of how the human brain functions during the process. Using data from functional magnetic resonance imaging (fMRI), a team from Massachusetts Institute of Technology mapped what different brain networks activate when subjects watch clips from a range of movies. They also saw how different executive networks in the brains are prioritized when watching easy versus difficult scenes.

Gravity makes dark matter clump into dense halos, indicated by bright patches, where galaxies form. In this simulation, a halo like the one that hosts the Milky Way forms and a smaller halo resembling the Large Magellanic Cloud falls toward it. SLAC and Stanford researchers, working with collaborators from the Dark Energy Survey, have used simulations like these to better understand the connection between dark matter and galaxy formation. Dark matter is the invisible force holding the universe together – or so we think. It makes up around 85% of all matter and around 27% of the universe's contents, but since we can't see it directly, we have to study its gravitational effects on galaxies and other cosmic structures.

The idea of controlling your dreams might sound like the plot of the latest science fiction blockbuster. But this mysterious gift is a reality for around 20 per cent of people, who are able to go on exciting trips in impossible worlds. Depicted in films such as'Inception', lucid dreaming could provide a useful link between the real world and the dream world. Scientists are trying to tap into the potential of lucid dreaming, helping people complete tasks like turning on lights or even driving virtual cars while asleep. Here are three tricks that could allow you to try it for yourself.