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Rationalized All-Atom Protein Design with Unified Multi-Modal Bayesian Flow
Designing functional proteins is a critical yet challenging problem due to the intricate interplay between backbone structures, sequences, and side-chains. Current approaches often decompose protein design into separate tasks, which can lead to accumulated errors, while recent efforts increasingly focus on all-atom protein design. However, we observe that existing all-atom generation approaches suffering from an information shortcut issue, where models inadvertently infer sequences from side-chain information, compromising their ability to accurately learn sequence distributions. To address this, we introduce a novel rationalized information flow strategy to eliminate the information shortcut. Furthermore, motivated by the advantages of Bayesian flows over differential equation-based methods, we propose the first Bayesian flow formulation for protein backbone orientations by recasting orientation modeling as an equivalent hyperspherical generation problem with antipodal symmetry. To validate, our method delivers consistently exceptional performance in both peptide and antibody design tasks.
3BASiL: An Algorithmic Framework for Sparseplus Low-Rank Compression of LLMs
Sparse plus Low-Rank (S + LR) decomposition of Large Language Models (LLMs) has emerged as a promising direction in model compression, aiming to decompose pre-trained model weights into a sum of sparse and low-rank matrices W S + LR. Despite recent progress, existing methods often suffer from substantial performance degradation compared to dense models. In this work, we introduce 3BASiL-TM, an efficient one-shot post-training method for (S + LR) decomposition of LLMs that addresses this gap. Our approach first introduces a novel 3-Block Alternating Direction Method of Multipliers (ADMM) method, termed 3BASiL, to minimize the layer-wise reconstruction error with convergence guarantees.
Continual Optimization with Symmetry Teleportation for Multi-Task Learning
Multi-task learning (MTL) is a widely explored paradigm that enables the simultaneous learning of multiple tasks using a single model. Despite numerous solutions, the key issues of optimization conflict and task imbalance remain under-addressed, limiting performance. Unlike existing optimization-based approaches that typically reweight task losses or gradients to mitigate conflicts or promote progress, we propose a novel approach based on Continual Optimization with Symmetry Teleportation (COST). During MTL optimization, when an optimization conflict arises, we seek an alternative loss-equivalent point on the loss landscape to reduce conflict. Specifically, we utilize a low-rank adapter (LoRA) to facilitate this practical teleportation by designing convergent, loss-invariant objectives. Additionally, we introduce a historical trajectory reuse strategy to continually leverage the benefits of advanced optimizers. Extensive experiments on multiple mainstream datasets demonstrate the effectiveness of our approach. COSTis a plug-and-play solution that enhances a wide range of existing MTL methods. When integrated with state-of-the-art methods, COSTachieves superior performance.
DeltaFormer: Unlock the State Space of Transformer
In recent years, large language models built around the Transformer architecture have achieved breakthrough progress in many fields. At the same time, certain weaknesses in these models have prompted further reflection, with the most fundamental concerns centered on the Transformer architecture itself. The Transformer offers high parallelism and can fully exploit the computing power of GPUs, which has enabled it to replace models such as LSTM over the past few years. However, high parallelism is not a free advantage, as it imposes fundamental limits on model performance. In particular, the problems that the logarithmic-precision Transformer architecture can solve are strictly bounded within the class TC0.
Spatial-Aware Decision-Making with Ring Attractors in Reinforcement Learning Systems
Ring attractors, mathematical models inspired by neural circuit dynamics, provide a biologically plausible mechanism to improve learning speed and accuracy in Reinforcement Learning (RL). Serving as specialized brain-inspired structures that encode spatial information and uncertainty, ring attractors explicitly encode the action space, facilitate the organization of neural activity, and enable the distribution of spatial representations across the neural network in the context of Deep Reinforcement Learning (DRL). These structures also provide temporal filtering that stabilizes action selection during exploration, for example, by preserving the continuity between rotation angles in robotic control or adjacency between tactical moves in game-like environments. The application of ring attractors in the action selection process involves mapping actions to specific locations on the ring and decoding the selected action based on neural activity. We investigate the application of ring attractors by both building an exogenous model and integrating them as part of DRL agents. Our approach significantly improves state-of-the-art performance on the Atari 100k benchmark, achieving a 53% increase in performance over selected baselines.
Open-Reasoner-Zero: An Open Source Approach to Scaling Up Reinforcement Learning on the Base Model
We introduce Open-Reasoner-Zero, the first open source implementation of largescale reasoning-oriented RL training on the base model focusing on scalability, simplicity and accessibility. Through extensive experiments, we demonstrate that a minimalist approach, vanilla PPO with GAE (ฮป = 1, ฮณ = 1) and straightforward rule-based rewards, without any KL regularization, is sufficient to scale up both benchmark performance and response length, replicating the scaling phenomenon observed in DeepSeek-R1-Zero.
QiMeng-SALV: Signal-Aware Learning for Verilog Code Generation
The remarkable progress of Large Language Models (LLMs) presents promising opportunities for Verilog code generation which is significantly important for automated circuit design. The lacking of meaningful functional rewards hinders the preference optimization based on Reinforcement Learning (RL) for producing functionally correct Verilog code. In this paper, we propose Signal-Aware Learning for Verilog code generation (QiMeng-SALV) by leveraging code segments of functionally correct output signal to optimize RL training. Considering Verilog code specifies the structural interconnection of hardware gates and wires so that different output signals are independent, the key insight of QiMeng-SALV is to extract verified signal-aware implementations in partially incorrect modules, so as to enhance the extraction of meaningful functional rewards. Roughly, we verify the functional correctness of signals in generated module by comparing with that of reference module in the training data. Then abstract syntax tree (AST) is employed to identify signal-aware code segments which can provide meaningful functional rewards from erroneous modules. Finally, we introduce signal-aware DPO which is optimized on the correct signal-level code segments, thereby preventing noise and interference from incorrect signals. The proposed QiMeng-SALV underscores the paradigm shift from conventional module-level to fine-grained signal-level optimization in Verilog code generation, addressing the issue of insufficient functional rewards. Experiments demonstrate that our method achieves state-of-the-art performance on VerilogEval and RTLLM, with a 7B parameter model matching the performance of the DeepSeek v3 671B model and significantly outperforming the leading open-source model CodeV trained on the same dataset.
Hadamax Encoding: Elevating Performance in Model-Free Atari
Neural network architectures have a large impact in machine learning. However, in the specific case of reinforcement learning, network architectures have remained notably simple, as changes often lead to small gains in performance. This work introduces a novel encoder architecture for pixel-based model-free reinforcement learning. The Hadamax (Hadamard max-pooling) encoder achieves state-of-the-art performance by max-pooling Hadamard products between GELU-activated parallel hidden layers. Based on the recent PQN algorithm, the Hadamax encoder achieves state-of-the-art model-free performance in the Atari-57 benchmark. Specifically, without applying any algorithmic hyperparameter modifications, Hadamax-PQN achieves an 80% performance gain over vanilla PQN and significantly surpasses Rainbow-DQN. For reproducibility, the full code is available on GitHub.
Stochastically Dominant Peer Prediction
Eliciting reliable human feedback is essential for many machine learning tasks, such as learning from noisy labels and aligning AI systems with human preferences. Peer prediction mechanisms incentivize truthful reporting without ground truth verification by scoring agents based on correlations with peers. Traditional mechanisms, which ensure that truth-telling maximizes the expected scores in equilibrium, can elicit honest information while assuming agents' utilities are linear functions of their scores. However, in practice, non-linear payment rules are usually preferred, or agents' utilities are inherently non-linear. We propose stochastically dominant truthfulness (SD-truthfulness) as a stronger guarantee: the score distribution of truth-telling stochastically dominates all other strategies, incentivizing truthful reporting for a wide range of monotone utility functions. Our first observation is that no existing peer prediction mechanism naturally satisfies this criterion without strong assumptions. A simple solution--rounding scores into binary lotteries--can enforce SD-truthfulness, but often degrades sensitivity, a key property related to fairness and statistical efficiency. We demonstrate how a more careful application of rounding can better preserve sensitivity. Furthermore, we introduce a new enforced agreement (EA) mechanism that is theoretically guaranteed to be SD-truthful in binary-signal settings and, under mild assumptions, empirically achieves the highest sensitivity among all known SD-truthful mechanisms.