Online artificial intelligence (AI) algorithms are an important component of digital health interventions. These online algorithms are designed to continually learn and improve their performance as streaming data is collected on individuals. Deploying online AI presents a key challenge: balancing adaptability of online AI with reproducibility. Online AI in digital interventions is a rapidly evolving area, driven by advances in algorithms, sensors, software, and devices. Digital health intervention development and deployment is a continuous process, where implementation - including the AI decision-making algorithm - is interspersed with cycles of re-development and optimization. Each deployment informs the next, making iterative deployment a defining characteristic of this field. This iterative nature underscores the importance of reproducibility: data collected across deployments must be accurately stored to have scientific utility, algorithm behavior must be auditable, and results must be comparable over time to facilitate scientific discovery and trustworthy refinement. This paper proposes a reproducible scientific workflow for developing, deploying, and analyzing online AI decision-making algorithms in digital health interventions. Grounded in practical experience from multiple real-world deployments, this workflow addresses key challenges to reproducibility across all phases of the online AI algorithm development life-cycle.

College students are increasingly affected by stress, anxiety, and depression, yet face barriers to traditional mental health care. This study evaluated the efficacy of a mobile health (mHealth) intervention, Mental Health Evaluation and Lookout Program (mHELP), which integrates a smartwatch sensor and machine learning (ML) algorithms for real-time stress detection and self-management. In a 12-week randomized controlled trial (n = 117), participants were assigned to a treatment group using mHELP's full suite of interventions or a control group using the app solely for real-time stress logging and weekly psychological assessments. The primary outcome, "Moments of Stress" (MS), was assessed via physiological and self-reported indicators and analyzed using Generalized Linear Mixed Models (GLMM) approaches. Similarly, secondary outcomes of psychological assessments, including the Generalized Anxiety Disorder-7 (GAD-7) for anxiety, the Patient Health Questionnaire (PHQ-8) for depression, and the Perceived Stress Scale (PSS), were also analyzed via GLMM. The finding of the objective measure, MS, indicates a substantial decrease in MS among the treatment group compared to the control group, while no notable between-group differences were observed in subjective scores of anxiety (GAD-7), depression (PHQ-8), or stress (PSS). However, the treatment group exhibited a clinically meaningful decline in GAD-7 and PSS scores. These findings underscore the potential of wearable-enabled mHealth tools to reduce acute stress in college populations and highlight the need for extended interventions and tailored features to address chronic symptoms like depression.

This paper discusses the use of Artificial Intelligence (AI) to enhance workplace productivity and employee well-being. By integrating machine learning (ML) techniques with neurobiological data, the proposed approaches ensure alignment with human ethical standards through value alignment models and Hierarchical Reinforcement Learning (HRL) for autonomous task management. The system utilizes biometric feedback from employees to generate personalized health prompts, fostering a supportive work environment that encourages physical activity. Additionally, we explore decentralized multi-agent systems for improved collaboration and decision-making frameworks that enhance transparency. Various approaches using ML techniques in conjunction with AI implementations are discussed. Together, these innovations aim to create a more productive and health-conscious workplace. These outcomes assist HR management and organizations in launching more rational career progression streams for employees and facilitating organizational transformation.

More than 5 million children under five years die from largely preventable or treatable medical conditions every year, with an overwhelmingly large proportion of deaths occurring in underdeveloped countries with low vaccination uptake. One of the United Nations' sustainable development goals (SDG 3) aims to end preventable deaths of newborns and children under five years of age. We focus on Nigeria, where the rate of infant mortality is appalling. In particular, low vaccination uptake in Nigeria is a major driver of more than 2,000 daily deaths of children under the age of five years. In this paper, we describe our collaboration with government partners in Nigeria to deploy ADVISER: AI-Driven Vaccination Intervention Optimiser. The framework, based on an integer linear program that seeks to maximize the cumulative probability of successful vaccination, is the first successful deployment of an AI-enabled toolchain for optimizing the allocation of health interventions in Nigeria. In this paper, we provide a background of the ADVISER framework and present results, lessons, and success stories of deploying ADVISER to more than 13,000 families in the state of Oyo, Nigeria.

Access to data, repetition and continued testing are preconditions for machine learning and – with the breadth and depth of data it consumes – the medical and healthcare industry provides AI with plenty of practice. Public health also happens to be where AI can make the most difference in terms of clinical need and cost-effectiveness of treatments. This of course is balanced with a need for rigorous testing because we're talking about human health rather than lower-stakes activities like gaming. As most biotech companies know, ethical and clinical testing is foundational to ensuring the safety of a therapy before it is unleashed on the public. COVID-19 taught us that population-level health solutions are the way of the future and AI, which works best at scale, can be used to optimise and speed up research and drug development and assist in the deployment of mass public health interventions.

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have discovered that people exhibit less faith in AI (artificial intelligence)-suggested preventive care interventions than that of human health expert interventions. Preventive care interventions are actions to reduce health risks, for example, signing up for a health screening, getting a vaccination, and increasing physical activity. The researchers discovered that highlighting the participation of a human health expert in an AI-suggested preventive care intervention can lead to better acceptance and success. These outcomes indicate that the human factor remains significant even as the healthcare industry adopts AI to diagnose, screen, and treat patients more competently. The researchers state that the results could also contribute to a more efficient design of AI-suggested interventions.

We combined a spoken dialog system that we developed to deliver brief health interventions with the fully autonomous humanoid robot (NAO). The dialog system is based on a framework facilitating Markov decision processes (MDP). It is optimized using reinforcement learning (RL) algorithms with data we collected from real user interactions. The system begins to learn optimal dialog strategies for initiative selection and for the type of confirmations that it uses during theinteraction. The health intervention, delivered by a 3D character instead of the NAO, has already been evaluated, with positive results in terms of task completion, ease of use, and future intention to use the system. The current spoken dialog system for the humanoid robot is a novelty and exists so far as a proof ofconcept.

This is fomenting the development of comprehensive modelling The COVID-19 pandemic has highlighted the importance and simulation to support the design of health interventions of in-silico epidemiological modelling in predicting and policies, and to guide decision-making in a variety of the dynamics of infectious diseases to inform health system domains [22, 49]. For example, simulations health policy and decision makers about suitable prevention have provided valuable insight to deal with public health and containment strategies. Work in this setting problems such as tobacco consumption in New Zealand [50], involves solving challenging inference and control and diabetes and obesity in the US [58]. They have been problems in individual-based models of ever increasing used to explore policy options such as those in maternal and complexity. Here we discuss recent breakthroughs antenatal care in Uganda [44], and applied to evaluate health in machine learning, specifically in simulation-based reform scenarios such as predicting changes in access to inference, and explore its potential as a novel venue primary care services in Portugal [21]. Their applicability for model calibration to support the design and evaluation in informing the design of cancer screening programmes of public health interventions. To further stimulate has been also discussed [42, 23]. Recently, simulations have research, we are developing software interfaces that informed the response to the COVID-19 outbreak [19].

Decisions in public health are almost always made in the context of uncertainty. Policy makers responsible for making important decisions are faced with the daunting task of choosing from many possible options. This task is called planning under uncertainty, and is particularly acute when addressing complex systems, such as issues of global health and development. Decision making under uncertainty is a challenging task, and all too often this uncertainty is averaged away to simplify results for policy makers. A popular way to approach this task is to formulate the problem at hand as a (partially observable) Markov decision process, (PO)MDP. This work aims to apply these AI efforts to challenging problems in health and development. In this paper, we developed a framework for optimal health policy design in a dynamic setting. We apply a stochastic dynamic programing approach to identify both the optimal time to change the health intervention policy and the optimal time to collect decision relevant information.

This paper presents an interactive narrative framework we have designed for games that promote health behavior change. The framework aims to address two key issues: player engagement with the game, and player adherence to the health behavior change-related homework they receive in the game. In this paper, we describe our narrative system that tackles these issues and a prototype game that promotes physical activity in which our narrative system is integrated.