Biomarker discovery from high-throughput transcriptomic data is crucial for advancing precision medicine. However, existing methods often neglect gene-gene regulatory relationships and lack stability across datasets, leading to conflation of spurious correlations with genuine causal effects. To address these issues, we develop a causal graph neural network (Causal-GNN) method that integrates causal inference with multi-layer graph neural networks (GNNs). The key innovation is the incorporation of causal effect estimation for identifying stable biomarkers, coupled with a GNN-based propensity scoring mechanism that leverages cross-gene regulatory networks. Experimental results demonstrate that our method achieves consistently high predictive accuracy across four distinct datasets and four independent classifiers. Moreover, it enables the identification of more stable biomarkers compared to traditional methods. Our work provides a robust, efficient, and biologically interpretable tool for biomarker discovery, demonstrating strong potential for broad application across medical disciplines.

Abstract--aintaining system stability and accurate position tracking is imperative in networked robotic systems, particularly for haptics-enabled human-robot interaction. Recent literature have integrated human biomechanics into the stabilizers implemented for teleoperation, enhancing force preservation while guaranteeing convergence and safety. However, position desynchronization due to imperfect communication and non-passive behaviors remains a challenge. We provide the mathematical design synthesis of the stabilizer and the proof of stability. We also conducted a series of grid simulations and systematic experiments and compared the performance with state-of-the-art solutions regarding varying time delays and environmental conditions. The proposed stabilizer is effective for various telerobotic applications requiring precise position synchronization.aintaining Recent literature have integrated human biomechanics into the stabilizers implemented for teleoperation, enhancing force preservation while guaranteeing convergence and safety. However, position desynchronization due to imperfect communication and non-passive behaviors remains a challenge. We provide the mathematical design synthesis of the stabilizer and the proof of stability.

Social anxiety is a prevalent mental health condition that can significantly impact overall well-being and quality of life. Despite its widespread effects, adequate support or treatment for social anxiety is often insufficient. Advances in technology, particularly in social robotics, offer promising opportunities to complement traditional mental health. As an initial step toward developing effective solutions, it is essential to understand the values that shape what is considered meaningful, acceptable, and helpful. In this study, a participatory design workshop was conducted with mental health academic researchers to elicit the underlying values that should inform the design of socially assistive robots for social anxiety support. Through creative, reflective, and envisioning activities, participants explored scenarios and design possibilities, allowing for systematic elicitation of values, expectations, needs, and preferences related to robot-supported interventions. The findings reveal rich insights into design-relevant values--including adaptivity, acceptance, and efficacy--that are core to support for individuals with social anxiety. This study highlights the significance of a research-led approach to value elicitation, emphasising user-centred and context-aware design considerations in the development of socially assistive robots.

Abstract--This study introduces a haptic shared control framework designed to teach human drivers advanced driving skills. In this context, shared control refers to a driving mode where the human driver collaborates with an autonomous driving system to control the steering of a vehicle simultaneously. Advanced driving skills are those necessary to safely push the vehicle to its handling limits in high-performance driving such as racing and emergency obstacle avoidance. Previous research has demonstrated the performance and safety benefits of shared control schemes using both subjective and objective evaluations. However, these schemes have not been assessed for their impact on skill acquisition on complex and demanding tasks. Prior research on long-term skill acquisition either applies haptic shared control to simple tasks or employs other feedback methods like visual and auditory aids. T o bridge this gap, this study creates a cyber racing coach framework based on the haptic shared control paradigm and evaluates its performance in helping human drivers acquire high-performance driving skills. The framework introduces (1) an autonomous driving system that is capable of cooperating with humans in a highly performant driving scenario; and (2) a haptic shared control mechanism along with a fading scheme to gradually reduce the steering assistance from autonomy based on the human driver's performance during training. Two benchmarks are considered: self-learning (no assistance) and full assistance during training. Results from a human subject study indicate that the proposed framework helps human drivers develop superior racing skills compared to the benchmarks, resulting in better performance and consistency. Advanced driving skills refer to a set of competencies that go beyond basic driving abilities in terms of situational awareness, hazard perception, risk management, and vehicle handling [1]. They are crucial in high-performance driving tasks such as racing, and can also improve safety in everyday driving [1], [2]. This work has been submitted to the IEEE for possible publication.

Ultimate is a sport where points are scored by passing a disc and catching it in the opposing team's end zone. In Ultimate, the player holding the disc cannot move, making field dynamics primarily driven by other players' movements. However, current literature in team sports has ignored quantitative evaluations of when players initiate such unlabeled movements in game situations. In this paper, we propose a quantitative evaluation method for movement initiation timing in Ultimate Frisbee. First, game footage was recorded using a drone camera, and players' positional data was obtained, which will be published as UltimateTrack dataset. Next, players' movement initiations were detected, and temporal counterfactual scenarios were generated by shifting the timing of movements using rule-based approaches. These scenarios were analyzed using a space evaluation metric based on soccer's pitch control reflecting the unique rules of Ultimate. By comparing the spatial evaluation values across scenarios, the difference between actual play and the most favorable counterfactual scenario was used to quantitatively assess the impact of movement timing. We validated our method and show that sequences in which the disc was actually thrown to the receiver received higher evaluation scores than the sequences without a throw. In practical verifications, the higher-skill group displays a broader distribution of time offsets from the model's optimal initiation point. These findings demonstrate that the proposed metric provides an objective means of assessing movement initiation timing, which has been difficult to quantify in unlabeled team sport plays.

This paper introduces a model for coordinating prosumers with heterogeneous distributed energy resources (DERs), participating in the local energy market (LEM) that interacts with the market-clearing entity. The proposed LEM scheme utilizes a data-driven, model-free reinforcement learning approach based on the multi-agent deep deterministic policy gradient (MADDPG) framework, enabling prosumers to make real-time decisions on whether to buy, sell, or refrain from any action while facilitating efficient coordination for optimal energy trading in a dynamic market. In addition, we investigate a price manipulation strategy using a variational auto encoder-generative adversarial network (VAE-GAN) model, which allows utilities to adjust price signals in a way that induces financial losses for the prosumers. Our results show that under adversarial pricing, heterogeneous prosumer groups, particularly those lacking generation capabilities, incur financial losses. The same outcome holds across LEMs of different sizes. As the market size increases, trading stabilizes and fairness improves through emergent cooperation among agents.