NASCAR's most thrilling race of the year finished at 3 a.m., fans at home were screwed & angry Bubba Wallace Mookie Betts becomes latest Dodgers player to skip White House visit, insists it's'not political' Brewers' ace Jacob Misiorowski is statistically untouchable as he faces Paul Skenes and the Pirates Lawmakers remember Sen Lindsey Graham's legacy of bipartisanship and humor Lindsey Graham's unexpected death sparks South Carolina special election Husband's chilling 911 call released in New Jersey homicide investigation Lindsey Graham's unexpected death sparks South Carolina special election, Trump weighs in OutKick Sports Charles Barkley actually beats someone at golf & it's the WNBA commissioner, UFC Sophie & USA as steaks A toddler's viral nap argument with her dad lost to a grandma's lawn fall, leaving Mickey and Minnie with no one to celebrate Welcome into another week of work where we're so far into the dog days of summer that the only sports options on the calendar today are WNBA games and the MLB Home Run Derby . Even the Tour de France has a day off to rest up. Let's get the week rolling with some observations from the weekend: How do I know Disney is a mess of a company? Last night, my family watched an episode of America's Funniest Videos where the show was giving away a trip on a Disney cruise for the funniest video. The battle was between a grandma who fell face first into her lawn and a cute toddler girl who got into a war of words with her father over taking a nap.

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Lindsey Graham, who has died aged 71, was a political survivor. His career as a Republican senator served as a telling barometer for the dramatically changing climate in his political party - and America - in the Donald Trump era. While there were certain issues central to Graham's political identity - including a hawkish foreign policy that focused on containing Russian global ambitions, support for Israel and regime change in Iran - his 23-year career in the Senate was marked by a willingness to adapt to the gale-force change of political winds that accompanied Trump's rise to power. Shortly after being elected to represent South Carolina in the Senate in 2002, Graham became a close ally of Senator John McCain, the Arizona Republican who, while a staunch conservative, developed a national reputation for political independence. When Graham ran for president in 2015, the idea of cooling partisan tensions and working with political opponents was one of his central messages. If I get to be president, we're going to open up a bar in the White House, Graham said.

US Senator Lindsey Graham dies after'brief and sudden illness', his office says To play this video you need to enable JavaScript in your browser. US Republican Senator Lindsey Graham has died following a brief and sudden illness. His office has released a statement saying he died on Saturday evening, adding that Graham's family asks for privacy during this incredibly difficult period. Elected to the Senate in 2002, the South Carolina politician was one of Washington's most influential voices on foreign policy and a key ally of Trump. He had just returned from Kyiv, where he met the Ukrainian President Volodymyr Zelensky on Friday.

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ROTC students at Old Dominion subdued and killed ISIS-linked gunman who left one dead, two wounded after shouting'Allahu Akbar' and opened fire Horrifying next twist in the Alexander brothers case: MAUREEN CALLAHAN exposes an unthinkable perversion that's been hiding in plain sight Kentucky mother and daughter turn down $26.5MILLION to sell their farms to secretive tech giant that wants to build data center there Hollywood icon who starred in Psycho after Hitchcock dubbed her'my new Grace Kelly' looks incredible at 95 Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back Tucker Carlson erupts at Trump adviser as she hurls'SLANDER' claim linking him to synagogue shooting Ben Affleck'scores $600m deal' with Netflix to sell his AI film start-up Long hair over 45 is ageing and try-hard. I've finally cut mine off. Alexander brothers' alleged HIGH SCHOOL rape video: Classmates speak out on sickening footage... as creepy unseen photos are exposed Heartbreaking video shows very elderly DoorDash driver shuffle down customer's driveway with coffee order because he is too poor to retire Amber Valletta, 52, was a '90s Vogue model who made movies with Sandra Bullock and Kate Hudson, see her now Model Cindy Crawford, 60, mocked for her'out of touch' morning routine: 'Nothing about this is normal' Britain has gone cottage cheese CRAZY! Britain has gone crazy for cottage cheese, new figures have revealed. At Tesco, demand has rocketed by 200 per cent over the last two years, amid a resurgence for the high-protein snack on TikTok.

We present an approach to denoising spatial transcriptomics images that is particularly effective for uncovering cell identities in the regime of ultra-low sequencing depths, and also allows for interpolation of gene expression. The method -- Spatial Transcriptomics via Adaptive Regularization and Kernels (STARK) -- augments kernel ridge regression with an incrementally adaptive graph Laplacian regularizer. In each iteration, we (1) perform kernel ridge regression with a fixed graph to update the image, and (2) update the graph based on the new image. The kernel ridge regression step involves reducing the infinite dimensional problem on a space of images to finite dimensions via a modified representer theorem. Starting with a purely spatial graph, and updating it as we improve our image makes the graph more robust to noise in low sequencing depth regimes. We show that the aforementioned approach optimizes a block-convex objective through an alternating minimization scheme wherein the sub-problems have closed form expressions that are easily computed. This perspective allows us to prove convergence of the iterates to a stationary point of this non-convex objective. Statistically, such stationary points converge to the ground truth with rate $\mathcal{O}(R^{-1/2})$ where $R$ is the number of reads. In numerical experiments on real spatial transcriptomics data, the denoising performance of STARK, evaluated in terms of label transfer accuracy, shows consistent improvement over the competing methods tested.

A supermassive black hole's star snack lit up the cosmos like never before. This artist's concept depicts a supermassive black hole in the process of shredding a massive star--at least 30 times the mass of our Sun--to pieces. Scientists propose this is what happened around the distant black hole referred to as J2245+3743, which in 2018, brightened dramatically to create the brightest black hole flare ever recorded, shining with the light of 10 trillion suns. Breakthroughs, discoveries, and DIY tips sent every weekday. It's hard to wrap your head around the fundamentals of a black hole .

Thousands of entrepreneurs are trying to rebuild the economy around AI. I set out to see how they're actually doing it. Earth, it's said, is home to more than 10,000 AI startups. The figure is a guess, of course--startups come, startups go. But last year, more than 2,000 of them got their first round of funding. As investors shovel their billions into AI, it's worth asking: What are all these creatures of the boom doing? I decided to approach as many recent AI founders as I could. The goal was not to try to pick winners but to see what it's like, on the ground, to build AI products--how AI tools have changed the nature of their work; how terrifying it is to compete in a crowded field.

Sign up to receive it in your inbox. Aside from a temporary love, or a new friend, you could easily stumble upon fabulous stage shows that were presented with such seriousness, often, that you wondered if--while watching the amazing Duelling Bankheads, for instance, or so many people who got up so brilliantly as Stevie Nicks on the Night of 1000 Stevies--you were high on the entertainment, or on dancing with your chosen community, or just amazed by what New York had to offer by way of creativity. Looking back, I can see that, for me at least, it was the combination of all three elements together that gave such hope about Manhattan's ability to foster noncommercial glamour, and to support young performers who were trying things out and seeing what stuck. Richard Move as Martha Graham. The shows I loved the most were at Jackie 60, spearheaded by the irreplaceable Chi Chi Valenti and Johnny Dynell, the resident d.j.