Globally, disparities in healthcare infrastructure remain stark, leaving countless communities without access to even basic services. Traditional infrastructure planning is often slow and inaccessible, and although many architects are actively delivering humanitarian and aid-driven hospital projects worldwide, these vital efforts still fall far short of the sheer scale and urgency of demand. This paper introduces MedBuild AI, a hybrid-intelligence framework that integrates large language models (LLMs) with deterministic expert systems to rebalance the early design and conceptual planning stages. As a web-based platform, it enables any region with satellite internet access to obtain guidance on modular, low-tech, low-cost medical building designs. The system operates through three agents: the first gathers local health intelligence via conversational interaction; the second translates this input into an architectural functional program through rule-based computation; and the third generates layouts and 3D models. By embedding computational negotiation into the design process, MedBuild AI fosters a reciprocal, inclusive, and equitable approach to healthcare planning, empowering communities and redefining agency in global healthcare architecture.

Despite the potential of generative AI (GenAI) design tools to enhance design processes, professionals often struggle to integrate AI into their workflows. Fundamental cognitive challenges include the need to specify all design criteria as distinct parameters upfront (intent formulation) and designers' reduced cognitive involvement in the design process due to cognitive offloading, which can lead to insufficient problem exploration, underspecification, and limited ability to evaluate outcomes. Motivated by these challenges, we envision novel metacognitive support agents that assist designers in working more reflectively with GenAI. To explore this vision, we conducted exploratory prototyping through a Wizard of Oz elicitation study with 20 mechanical designers probing multiple metacognitive support strategies. We found that agent-supported users created more feasible designs than non-supported users, with differing impacts between support strategies. Based on these findings, we discuss opportunities and tradeoffs of metacognitive support agents and considerations for future AI-based design tools.

The discovery of Metal-Organic Frameworks (MOFs) with application-specific properties remains a central challenge in materials chemistry, owing to the immense size and complexity of their structural design space. Conventional computational screening techniques such as molecular simulations and density functional theory (DFT), while accurate, are computationally prohibitive at scale. Machine learning offers an exciting alternative by leveraging data-driven approaches to accelerate materials discovery. The complexity of MOFs, with their extended periodic structures and diverse topologies, creates both opportunities and challenges for generative modeling approaches. To address these challenges, we present a reinforcement learning-enhanced, transformer-based framework for the de novo design of MOFs. Central to our approach is MOFid, a chemically-informed string representation encoding both connectivity and topology, enabling scalable generative modeling. Our pipeline comprises three components: (1) a generative GPT model trained on MOFid sequences, (2) MOFormer, a transformer-based property predictor, and (3) a reinforcement learning (RL) module that optimizes generated candidates via property-guided reward functions. By integrating property feedback into sequence generation, our method drives the model toward synthesizable, topologically valid MOFs with desired functional attributes. This work demonstrates the potential of large language models, when coupled with reinforcement learning, to accelerate inverse design in reticular chemistry and unlock new frontiers in computational MOF discovery.

We propose a new concept, Evolution 6.0, which represents the evolution of robotics driven by Generative AI. When a robot lacks the necessary tools to accomplish a task requested by a human, it autonomously designs the required instruments and learns how to use them to achieve the goal. Evolution 6.0 is an autonomous robotic system powered by Vision-Language Models (VLMs), Vision-Language Action (VLA) models, and Text-to-3D generative models for tool design and task execution. The system comprises two key modules: the Tool Generation Module, which fabricates task-specific tools from visual and textual data, and the Action Generation Module, which converts natural language instructions into robotic actions. It integrates QwenVLM for environmental understanding, OpenVLA for task execution, and Llama-Mesh for 3D tool generation. Evaluation results demonstrate a 90% success rate for tool generation with a 10-second inference time, and action generation achieving 83.5% in physical and visual generalization, 70% in motion generalization, and 37% in semantic generalization. Future improvements will focus on bimanual manipulation, expanded task capabilities, and enhanced environmental interpretation to improve real-world adaptability.

A generative design based on topology optimization provides diverse alternatives as entities in a computational model with a high design degree. However, as the diversity of the generated alternatives increases, the cognitive burden on designers to select the most appropriate alternatives also increases. Whereas the concept identification approach, which finds various categories of entities, is an effective means to structure alternatives, evaluation of their similarities is challenging due to shape diversity. To address this challenge, this study proposes a concept identification framework for generative design using deep learning (DL) techniques. One of the key abilities of DL is the automatic learning of different representations of a specific task. Deep concept identification finds various categories that provide insights into the mapping relationships between geometric properties and structural performance through representation learning using DL. The proposed framework generates diverse alternatives using a generative design technique, clusters the alternatives into several categories using a DL technique, and arranges these categories for design practice using a classification model. This study demonstrates its fundamental capabilities by implementing variational deep embedding, a generative and clustering model based on the DL paradigm, and logistic regression as a classification model. A simplified design problem of a two-dimensional bridge structure is applied as a case study to validate the proposed framework. Although designers are required to determine the viewing aspect level by setting the number of concepts, this implementation presents the identified concepts and their relationships in the form of a decision tree based on a specified level.

The recent advancements in machine learning techniques have steered us towards the data-driven design of products. Motivated by this objective, the present study proposes an automated design methodology that employs data-driven methods to generate new designs of soft actuators. One of the bottlenecks in the data-driven automated design process is having publicly available data to train the model. Due to its unavailability, a synthetic data set of soft pneumatic network (Pneu-net) actuators has been created. The parametric design data set for the training of the generative model is created using data augmentation. Next, the Gaussian mixture model has been applied to generate novel parametric designs of Pneu-net actuators. The distance-based metric defines the novelty and diversity of the generated designs. In addition, it is noteworthy that the model has the potential to generate a multimodal Pneu-net actuator that could perform in-plane bending and out-of-plane twisting. Later, the novel design is passed through finite element analysis to evaluate the quality of the generated design. Moreover, the trajectory of each category of Pneu-net actuators evaluates the performance of the generated Pneu-net actuators and emphasizes the necessity of multimodal actuation. The proposed model could accelerate the design of new soft robots by selecting a soft actuator from the developed novel pool of soft actuators.

The Three-Body Problem has fascinated scientists for centuries and it has been crucial in the design of modern space missions. Recent developments in Generative Artificial Intelligence hold transformative promise for addressing this longstanding problem. This work investigates the use of Variational Autoencoder (VAE) and its internal representation to generate periodic orbits. We utilize a comprehensive dataset of periodic orbits in the Circular Restricted Three-Body Problem (CR3BP) to train deep-learning architectures that capture key orbital characteristics, and we set up physical evaluation metrics for the generated trajectories. Through this investigation, we seek to enhance the understanding of how Generative AI can improve space mission planning and astrodynamics research, leading to novel, data-driven approaches in the field.

Two fundamental challenges face generative models in engineering applications: the acquisition of high-performing, diverse datasets, and the adherence to precise constraints in generated designs. We propose a novel approach combining optimization, constraint satisfaction, and language models to tackle these challenges in architectural design. Our method uses Quality-Diversity (QD) to generate a diverse, high-performing dataset. We then fine-tune a language model with this dataset to generate high-level designs. These designs are then refined into detailed, constraint-compliant layouts using the Wave Function Collapse algorithm. Our system demonstrates reliable adherence to textual guidance, enabling the generation of layouts with targeted architectural and performance features. Crucially, our results indicate that data synthesized through the evolutionary search of QD not only improves overall model performance but is essential for the model's ability to closely adhere to textual guidance. This improvement underscores the pivotal role evolutionary computation can play in creating the datasets key to training generative models for design. Web article at https://tilegpt.github.io

The scarcity of green spaces, in urban environments, consists a critical challenge. There are multiple adverse effects, impacting the health and well-being of the citizens. Small scale interventions, e.g. pocket parks, is a viable solution, but comes with multiple constraints, involving the design and implementation over a specific area. In this study, we harness the capabilities of generative AI for multi-scale intervention planning, focusing on nature based solutions. By leveraging image-to-image and image inpainting algorithms, we propose a methodology to address the green space deficit in urban areas. Focusing on two alleys in Thessaloniki, where greenery is lacking, we demonstrate the efficacy of our approach in visualizing NBS interventions. Our findings underscore the transformative potential of emerging technologies in shaping the future of urban intervention planning processes.

In traditional human living environment landscape design, the establishment of three-dimensional models is an essential step for designers to intuitively present the spatial relationships of design elements, as well as a foundation for conducting landscape analysis on the site. Rapidly and effectively generating beautiful and realistic landscape spaces is a significant challenge faced by designers. Although generative design has been widely applied in related fields, they mostly generate three-dimensional models through the restriction of indicator parameters. However, the elements of landscape design are complex and have unique requirements, making it difficult to generate designs from the perspective of indicator limitations. To address these issues, this study proposes a park space generative design system based on deep learning technology. This system generates design plans based on the topological relationships of landscape elements, then vectorizes the plan element information, and uses Grasshopper to generate three-dimensional models while synchronously fine-tuning parameters, rapidly completing the entire process from basic site conditions to model effect analysis. Experimental results show that: (1) the system, with the aid of AI-assisted technology, can rapidly generate space green space schemes that meet the designer's perspective based on site conditions; (2) this study has vectorized and three-dimensionalized various types of landscape design elements based on semantic information; (3) the analysis and visualization module constructed in this study can perform landscape analysis on the generated three-dimensional models and produce node effect diagrams, allowing users to modify the design in real time based on the effects, thus enhancing the system's interactivity.