Predicting a song's commercial success prior to its release remains an open and critical research challenge for the music industry. Early prediction of music popularity informs strategic decisions, creative planning, and marketing. Existing methods suffer from four limitations:(i) temporal dynamics in audio and lyrics are averaged away; (ii) lyrics are represented as a bag of words, disregarding compositional structure and affective semantics; (iii) artist- and song-level historical performance is ignored; and (iv) multimodal fusion approaches rely on simple feature concatenation, resulting in poorly aligned shared representations. To address these limitations, we introduce GAMENet, an end-to-end multimodal deep learning architecture for music popularity prediction. GAMENet integrates modality-specific experts for audio, lyrics, and social metadata through an adaptive gating mechanism. We use audio features from Music4AllOnion processed via OnionEnsembleAENet, a network of autoencoders designed for robust feature extraction; lyric embeddings derived through a large language model pipeline; and newly introduced Career Trajectory Dynamics (CTD) features that capture multi-year artist career momentum and song-level trajectory statistics. Using the Music4All dataset (113k tracks), previously explored in MIR tasks but not popularity prediction, GAMENet achieves a 12% improvement in R^2 over direct multimodal feature concatenation. Spotify audio descriptors alone yield an R^2 of 0.13. Integrating aggregate CTD features increases this to 0.69, with an additional 7% gain from temporal CTD features. We further validate robustness using the SpotGenTrack Popularity Dataset (100k tracks), achieving a 16% improvement over the previous baseline. Extensive ablations confirm the model's effectiveness and the distinct contribution of each modality.

Models of human behavior in game-theoretic settings often distinguish between strategic behavior, in which a player both reasons about how others will act and best responds to these beliefs, and "level-0" non-strategic behavior, in which they do not respond to explicit beliefs about others. The state of the art for predicting human behavior on unrepeated simultaneous-move games is GameNet, a neural network that learns extremely complex level-0 specifications from data. The current paper makes three contributions. First, it shows that GameNet's level-0 specifications are too powerful, because they are capable of strategic reasoning. Second, it introduces a novel neural network architecture (dubbed ElementaryNet) and proves that it is only capable of nonstrategic behavior. Third, it describes an extensive experimental evaluation of ElementaryNet. Our overall findings are that (1) ElementaryNet dramatically underperforms GameNet when neither model is allowed to explicitly model higher level agents who best-respond to the model's predictions, indicating that good performance on our dataset requires a model capable of strategic reasoning; (2) that the two models achieve statistically indistinguishable performance when such higher-level agents are introduced, meaning that ElementaryNet's restriction to a non-strategic level-0 specification does not degrade model performance; and (3) that this continues to hold even when ElementaryNet is restricted to a set of level-0 building blocks previously introduced in the literature, with only the functional form being learned by the neural network.

Recent progress in deep learning is revolutionizing the healthcare domain including providing solutions to medication recommendations, especially recommending medication combination for patients with complex health conditions. Existing approaches either do not customize based on patient health history, or ignore existing knowledge on drug-drug interactions (DDI) that might lead to adverse outcomes. To fill this gap, we propose the Graph Augmented Memory Networks (GAMENet), which integrates the drug-drug interactions knowledge graph by a memory module implemented as a graph convolutional networks, and models longitudinal patient records as the query. It is trained end-to-end to provide safe and personalized recommendation of medication combination. We demonstrate the effectiveness and safety of GAMENet by comparing with several state-of-the-art methods on real EHR data. GAMENet outperformed all baselines in all effectiveness measures, and also achieved 3.60% DDI rate reduction from existing EHR data.