In the field of psychopathology, Ecological Momentary Assessment (EMA) methodological advancements have offered new opportunities to collect time-intensive, repeated and intra-individual measurements. This way, a large amount of data has become available, providing the means for further exploring mental disorders. Consequently, advanced machine learning (ML) methods are needed to understand data characteristics and uncover hidden and meaningful relationships regarding the underlying complex psychological processes. Among other uses, ML facilitates the identification of similar patterns in data of different individuals through clustering. This paper focuses on clustering multivariate time-series (MTS) data of individuals into several groups. Since clustering is an unsupervised problem, it is challenging to assess whether the resulting grouping is successful. Thus, we investigate different clustering methods based on different distance measures and assess them for the stability and quality of the derived clusters. These clustering steps are illustrated on a real-world EMA dataset, including 33 individuals and 15 variables. Through evaluation, the results of kernel-based clustering methods appear promising to identify meaningful groups in the data. So, efficient representations of EMA data play an important role in clustering.

Despite the success of deep neural networks (DNNs) for real-world applications over time-series data such as mobile health, little is known about how to train robust DNNs for time-series domain due to its unique characteristics compared to images and text data. In this paper, we propose a novel algorithmic framework referred as RObust Training for Time-Series (RO-TS) to create robust DNNs for time-series classification tasks. Specifically, we formulate a min-max optimization problem over the model parameters by explicitly reasoning about the robustness criteria in terms of additive perturbations to time-series inputs measured by the global alignment kernel (GAK) based distance. We also show the generality and advantages of our formulation using the summation structure over time-series alignments by relating both GAK and dynamic time warping (DTW). This problem is an instance of a family of compositional min-max optimization problems, which are challenging and open with unclear theoretical guarantee. We propose a principled stochastic compositional alternating gradient descent ascent (SCAGDA) algorithm for this family of optimization problems. Unlike traditional methods for time-series that require approximate computation of distance measures, SCAGDA approximates the GAK based distance on-the-fly using a moving average approach. We theoretically analyze the convergence rate of SCAGDA and provide strong theoretical support for the estimation of GAK based distance. Our experiments on real-world benchmarks demonstrate that RO-TS creates more robust DNNs when compared to adversarial training using prior methods that rely on data augmentation or new definitions of loss functions. We also demonstrate the importance of GAK for time-series data over the Euclidean distance. The source code of RO-TS algorithms is available at https://github.com/tahabelkhouja/Robust-Training-for-Time-Series

A large fraction of the electronic health records consists of clinical measurements collected over time, such as blood tests, which provide important information about the health status of a patient. These sequences of clinical measurements are naturally represented as time series, characterized by multiple variables and the presence of missing data, which complicate analysis. In this work, we propose a surgical site infection detection framework for patients undergoing colorectal cancer surgery that is completely unsupervised, hence alleviating the problem of getting access to labelled training data. The framework is based on powerful kernels for multivariate time series that account for missing data when computing similarities. Our approach show superior performance compared to baselines that have to resort to imputation techniques and performs comparable to a supervised classification baseline.