diffsurv
- North America > United States > Oregon (0.04)
- North America > United States > New Jersey > Atlantic County > Atlantic City (0.04)
- North America > United States > California > Santa Clara County > Palo Alto (0.04)
- Research Report > New Finding (1.00)
- Research Report > Experimental Study (1.00)
- Health & Medicine > Diagnostic Medicine (0.67)
- Law > Civil Rights & Constitutional Law (0.54)
Differentiable sorting for censored time-to-event data.
Survival analysis is a crucial semi-supervised task in machine learning with significant real-world applications, especially in healthcare. The most common approach to survival analysis, Cox's partial likelihood, can be interpreted as a ranking model optimized on a lower bound of the concordance index. We follow these connections further, with listwise ranking losses that allow for a relaxation of the pairwise independence assumption. Given the inherent transitivity of ranking, we explore differentiable sorting networks as a means to introduce a stronger transitive inductive bias during optimization.
- North America > United States > Oregon (0.04)
- North America > United States > New Jersey > Atlantic County > Atlantic City (0.04)
- North America > United States > California > Santa Clara County > Palo Alto (0.04)
- Research Report > New Finding (1.00)
- Research Report > Experimental Study (1.00)
- Health & Medicine > Diagnostic Medicine (0.67)
- Health & Medicine > Therapeutic Area > Oncology (0.46)
Differentiable sorting for censored time-to-event data.
Survival analysis is a crucial semi-supervised task in machine learning with significant real-world applications, especially in healthcare. The most common approach to survival analysis, Cox's partial likelihood, can be interpreted as a ranking model optimized on a lower bound of the concordance index. We follow these connections further, with listwise ranking losses that allow for a relaxation of the pairwise independence assumption. Given the inherent transitivity of ranking, we explore differentiable sorting networks as a means to introduce a stronger transitive inductive bias during optimization. We propose a novel method, Diffsurv, to overcome this limitation by extending differentiable sorting methods to handle censored tasks.
Diffsurv: Differentiable sorting for censored time-to-event data
Vauvelle, Andre, Wild, Benjamin, Cakiroglu, Aylin, Eils, Roland, Denaxas, Spiros
Survival analysis is a crucial semi-supervised task in machine learning with numerous real-world applications, particularly in healthcare. Currently, the most common approach to survival analysis is based on Cox's partial likelihood, which can be interpreted as a ranking model optimized on a lower bound of the concordance index. This relation between ranking models and Cox's partial likelihood considers only pairwise comparisons. Recent work has developed differentiable sorting methods which relax this pairwise independence assumption, enabling the ranking of sets of samples. However, current differentiable sorting methods cannot account for censoring, a key factor in many real-world datasets. To address this limitation, we propose a novel method called Diffsurv. We extend differentiable sorting methods to handle censored tasks by predicting matrices of possible permutations that take into account the label uncertainty introduced by censored samples. We contrast this approach with methods derived from partial likelihood and ranking losses. Our experiments show that Diffsurv outperforms established baselines in various simulated and real-world risk prediction scenarios. Additionally, we demonstrate the benefits of the algorithmic supervision enabled by Diffsurv by presenting a novel method for top-k risk prediction that outperforms current methods.
- Law > Civil Rights & Constitutional Law (1.00)
- Health & Medicine > Therapeutic Area > Oncology (0.93)