Microscopy such as Scanning Tunneling Microscopy (STM), Atomic Force Microscopy (AFM) and Scanning Electron Microscopy (SEM) are essential tools in material imaging at micro- and nanoscale resolutions to extract physical knowledge and materials structure-property relationships. However, tuning microscopy controls (e.g. scanning speed, current setpoint, tip bias etc.) to obtain a high-quality of images is a non-trivial and time-consuming effort. On the other hand, with sub-standard images, the key features are not accurately discovered due to noise and artifacts, leading to erroneous analysis. Existing denoising models mostly build on generalizing the weak signals as noises while the strong signals are enhanced as key features, which is not always the case in microscopy images, thus can completely erase a significant amount of hidden physical information. To address these limitations, we propose a global denoising model (GDM) to smartly remove artifacts of microscopy images while preserving weaker but physically important features. The proposed model is developed based on 1) first designing a two-imaging input channel of non-pair and goal specific pre-processed images with user-defined trade-off information between two channels and 2) then integrating a loss function of pixel- and fast Fourier-transformed (FFT) based on training the U-net model. We compared the proposed GDM with the non-FFT denoising model over STM-generated images of Copper(Cu) and Silicon(Si) materials, AFM-generated Pantoea sp.YR343 bio-film images and SEM-generated plastic degradation images. We believe this proposed workflow can be extended to improve other microscopy image quality and will benefit the experimentalists with the proposed design flexibility to smartly tune via domain-experts preferences.

First provide a summary of the paper, and then address the following criteria: Quality, clarity, originality and significance. This paper proposes a denoising algorithm based on non-local image statistics and patch repetition by combining the advantages of NL-means and Exponentially Weighted Aggregation (EWA). The computation of the aggregated estimator is done using MCMC and results are comparable to state-of-the-art algorithms. Pluses: 1) the method seems simple and straightforward to implement. Minus: In terms of explaining *why* the method works, the text leaves something to be desired. E.g., in the second paragraph of section 7 (The proposed implementation proceeds in two identical iterations.)

Here we propose "GainTuning", a

Convolutional denoising autoencoders (DAEs) are powerful tools for image restoration. However, they inherit a key limitation of convolutional neural networks (CNNs): they tend to recover low-frequency features, such as smooth regions, more effectively than high-frequency details. This leads to the loss of fine details, which is particularly problematic in dental radiographs where preserving subtle anatomical structures is crucial. While self-attention mechanisms can help mitigate this issue by emphasizing important features, conventional attention methods often prioritize features corresponding to cleaner regions and may overlook those obscured by noise. To address this limitation, we propose a noise-aware self-attention method, which allows the model to effectively focus on and recover key features even within noisy regions. Building on this approach, we introduce the noise-aware attention-enhanced denoising autoencoder (NAADA) network for enhancing noisy panoramic dental radiographs. Compared with the recent state of the art (and much heavier) methods like Uformer, MResDNN etc., our method improves the reconstruction of fine details, ensuring better image quality and diagnostic accuracy.

Computer vision has transformed medical diagnosis, treatment, and research through advanced image processing and machine learning techniques. Fracture classification, a critical area in healthcare, has greatly benefited from these advancements, yet accurate detection is challenged by complex patterns and image noise. Bit plane slicing enhances medical images by reducing noise interference and extracting informative features. This research explores partial denoising techniques to provide practical solutions for improved fracture analysis, ultimately enhancing patient care. The study explores deep learning model DenseNet and handcrafted feature extraction. Decision Tree and Random Forest, were employed to train and evaluate distinct image representations. These include the original image, the concatenation of the four bit planes from the LSB as well as MSB, the fully denoised image, and an image consisting of 6 bit planes from MSB and 2 denoised bit planes from LSB. The purpose of forming these diverse image representations is to analyze SNR as well as classification accuracy and identify the bit planes that contain the most informative features. Moreover, the study delves into the significance of partial denoising techniques in preserving crucial features, leading to improvements in classification results. Notably, this study shows that employing the Random Forest classifier, the partially denoised image representation exhibited a testing accuracy of 95.61% surpassing the performance of other image representations. The outcomes of this research provide valuable insights into the development of efficient preprocessing, feature extraction and classification approaches for fracture identification. By enhancing diagnostic accuracy, these advancements hold the potential to positively impact patient care and overall medical outcomes.

Artifact detection algorithms are crucial to correcting the output generated by diffusion models. However, because of the variety of artifact forms, existing methods require substantial annotated data for training. This requirement limits their scalability and efficiency, which restricts their wide application. This paper shows that the similarity of denoised images between consecutive time steps during the sampling process is related to the severity of artifacts in images generated by diffusion models. Building on this observation, we introduce the concept of Similarity Trajectory to characterize the sampling process and its correlation with the image artifacts presented. Using an annotated data set of 680 images, which is only 0.1% of the amount of data used in the prior work, we trained a classifier on these trajectories to predict the presence of artifacts in images. By performing 10-fold validation testing on the balanced annotated data set, the classifier can achieve an accuracy of 72.35%, highlighting the connection between the Similarity Trajectory and the occurrence of artifacts. This approach enables differentiation between artifact-exhibiting and natural-looking images using limited training data.

In contrast to non-medical image denoising, where enhancing image clarity is the primary goal, medical image denoising warrants preservation of crucial features without introduction of new artifacts. However, many denoising methods that improve the clarity of the image, inadvertently alter critical information of the denoised images, potentially compromising classification performance and diagnostic quality. Additionally, supervised denoising methods are not very practical in medical image domain, since a \emph{ground truth} denoised version of a noisy medical image is often extremely challenging to obtain. In this paper, we tackle both of these problems by introducing a novel neural network based method -- \emph{Contextual Checkerboard Denoising}, that can learn denoising from only a dataset of noisy images, while preserving crucial anatomical details necessary for image classification/analysis. We perform our experimentation on real Optical Coherence Tomography (OCT) images, and empirically demonstrate that our proposed method significantly improves image quality, providing clearer and more detailed OCT images, while enhancing diagnostic accuracy.

The remarkable advances in deep learning have led to the emergence of many off-the-shelf classifiers, e.g., large pre-trained models. However, since they are typically trained on clean data, they remain vulnerable to adversarial attacks. Despite this vulnerability, their superior performance and transferability make off-the-shelf classifiers still valuable in practice, demanding further work to provide adversarial robustness for them in a post-hoc manner. A recently proposed method, denoised smoothing, leverages a denoiser model in front of the classifier to obtain provable robustness without additional training. However, the denoiser often creates hallucination, i.e., images that have lost the semantics of their originally assigned class, leading to a drop in robustness. Furthermore, its noise-and-denoise procedure introduces a significant distribution shift from the original distribution, causing the denoised smoothing framework to achieve sub-optimal robustness. In this paper, we introduce Fine-Tuning with Confidence-Aware Denoised Image Selection (FT-CADIS), a novel fine-tuning scheme to enhance the certified robustness of off-the-shelf classifiers. FT-CADIS is inspired by the observation that the confidence of off-the-shelf classifiers can effectively identify hallucinated images during denoised smoothing. Based on this, we develop a confidence-aware training objective to handle such hallucinated images and improve the stability of fine-tuning from denoised images. In this way, the classifier can be fine-tuned using only images that are beneficial for adversarial robustness. We also find that such a fine-tuning can be done by updating a small fraction of parameters of the classifier. Extensive experiments demonstrate that FT-CADIS has established the state-of-the-art certified robustness among denoised smoothing methods across all $\ell_2$-adversary radius in various benchmarks.

With the proliferation of sophisticated cameras in modern society, the demand for accurate and visually pleasing images is increasing. However, the quality of an image captured by a camera may be degraded by noise. Thus, some processing of images is required to filter out the noise without losing vital image features. Even though the current literature offers a variety of denoising methods, the fidelity and efficacy of their denoising are sometimes uncertain. Thus, here we propose a novel and computationally efficient image denoising method that is capable of producing accurate images. To preserve image smoothness, this method inputs patches partitioned from the image rather than pixels. Then, it performs denoising on the manifold underlying the patch-space rather than that in the image domain to better preserve the features across the whole image. We validate the performance of this method against benchmark image processing methods.

Stacked sparse denoising autoencoders (SSDAs) have recently been shown to be successful at removing noise from corrupted images. However, like most denoising techniques, the SSDA is not robust to variation in noise types beyond what it has seen during training. To address this limitation, we present the adaptive multi-column stacked sparse denoising autoencoder (AMC-SSDA), a novel technique of combining multiple SSDAs by (1) computing optimal column weights via solving a nonlinear optimization program and (2) training a separate network to predict the optimal weights. We eliminate the need to determine the type of noise, let alone its statistics, at test time and even show that the system can be robust to noise not seen in the training set. We show that state-of-the-art denoising performance can be achieved with a single system on a variety of different noise types. Additionally, we demonstrate the efficacy of AMC-SSDA as a preprocessing (denoising) algorithm by achieving strong classification performance on corrupted MNIST digits.