DeNeRD: an AI-based method to process whole images of the brain


Researchers at the University of Zurich's Brain Research Institute have recently developed a technique to automatically detect neurons of different types in a variety of brain regions at different developmental stages. They presented this deep learning-based tool, called DeNeRD, in a paper published in Nature Scientific Reports. Mapping the structure of the mammalian brain at the cellular level is an important, yet demanding task, which typically involves capturing specific anatomical features and analyzing them. In the past, researchers were able to gather several interesting observations and insights about the mammalian brain's structure using classical histological and stereological techniques. Although these methods have proved to be very useful for studying the anatomy of the brain, carrying out a truly brain-wide analysis typically requires a different approach.