Recent results [1, 2] indicate that the current VLSI paradigm based on CMOS technology can be hardly extended beyond the 10-nm frontier: in this range the sensitivity of parameters (most importantly, the gate voltage threshold) of silicon field-effect transistors to inevitable fabrication spreads grows exponentially. This sensitivity will probably send the fabrication facilities costs skyrocketing, and may lead to the end of Moore's Law some time during the next decade. There is a growing consensus that the impending Moore's Law crisis may be preempted by a radical paradigm shift from the purely CMOS technology to hybrid CMOS/nanodevice circuits, e.g., those of "CMOL" variety (Figure 1). Such circuits (see, e.g., Ref. 3 for their recent review) would combine a level of advanced CMOS devices fabricated by the lithographic patterning, and two-layer nanowire crossbar formed, e.g., by nanoimprint, with nanowires connected by simple, similar, two-terminal nanodevices at each crosspoint. For such devices, molecular single-electron latching switches [4] are presently the leading candidates, in particular because they may be fabricated using the self-assembled monolayer (SAM) technique which already gave reproducible results for simpler molecular devices [5].

Black-box models, such as deep neural networks, exhibit superior predictive performances, but understanding their behavior is notoriously difficult. Many explainable artificial intelligence methods have been proposed to reveal the decision-making processes of black box models. However, their applications in high-stakes domains remain limited. Recently proposed neural additive models (NAM) have achieved state-of-the-art interpretable machine learning. NAM can provide straightforward interpretations with slight performance sacrifices compared with multi-layer perceptron. However, NAM can only model 1$^{\text{st}}$-order feature interactions; thus, it cannot capture the co-relationships between input features. To overcome this problem, we propose a novel interpretable machine learning method called higher-order neural additive models (HONAM) and a feature interaction method for high interpretability. HONAM can model arbitrary orders of feature interactions. Therefore, it can provide the high predictive performance and interpretability that high-stakes domains need. In addition, we propose a novel hidden unit to effectively learn sharp-shape functions. We conducted experiments using various real-world datasets to examine the effectiveness of HONAM. Furthermore, we demonstrate that HONAM can achieve fair AI with a slight performance sacrifice. The source code for HONAM is publicly available.

With the emergence of online forums associated with major diseases, such as diabetes mellitus, many patients are increasingly dependent on such disease-specific social networks to gain access to additional resources. Among these patients, it is common for them to stick to one disease-specific social network, although their desired resources might be spread over multiple social networks, such as patients with similar questions and concerns. Motivated by this application, in this paper, we focus on cross network link recommendation, which aims to identify similar users across multiple heterogeneous social networks. The problem setting is different from existing work on cross network link prediction, which either tries to link accounts of the same user from different social networks, or aims to match users with complementary expertise or interest. To approach the problem of cross network link recommendation, we propose to jointly decompose the user-keyword matrices from multiple social networks, while requiring them to share the same topics and user group-topic association matrices. This constraint comes from the fact that social networks dedicated to the same disease tend to share the same topics as well as the interests of users groups in certain topics. Based on this intuition, we construct a generic optimization framework, provide four instantiations and an iterative optimization algorithm with performance analysis. In the experiments, we demonstrate the superiority of the proposed algorithm over state-of-the-art techniques on various real-world data sets.

This extended abstract outlines my invited keynote presentation of the recent work on neuromorphic networks ("CrossNets") based on hybrid CMOS/nanoelectronic ("CMOL") circuits, in the space-saving Q/A format.

Hybrid "CMOL" integrated circuits, combining CMOS subsystem with nanowire crossbars and simple two-terminal nanodevices, promise to extend the exponential Moore-Law development of microelectronics into the sub-10-nm range. We are developing neuromorphic network ("CrossNet") architectures for this future technology, in which neural cell bodies are implemented in CMOS, nanowires are used as axons and dendrites, while nanodevices (bistable latching switches) are used as elementary synapses. We have shown how CrossNets may be trained to perform pattern recovery and classification despite the limitations imposed by the CMOL hardware.

Hybrid "CMOL" integrated circuits, combining CMOS subsystem with nanowire crossbars and simple two-terminal nanodevices, promise to extend the exponential Moore-Law development of microelectronics into the sub-10-nm range. We are developing neuromorphic network ("CrossNet") architectures for this future technology, in which neural cell bodies are implemented in CMOS, nanowires are used as axons and dendrites, while nanodevices (bistable latching switches) are used as elementary synapses. We have shown how CrossNets may be trained to perform pattern recovery and classification despite the limitations imposed by the CMOL hardware.

Hybrid "CMOL" integrated circuits, combining CMOS subsystem with nanowire crossbars and simple two-terminal nanodevices, promise to extend the exponential Moore-Law development of microelectronics into the sub-10-nm range. We are developing neuromorphic network ("CrossNet") architectures for this future technology, in which neural cell bodies are implemented in CMOS, nanowires are used as axons and dendrites, while nanodevices (bistable latching switches) are used as elementary synapses. We have shown how CrossNets may be trained to perform pattern recovery and classification despite the limitations imposed by the CMOL hardware.