Understanding the organization of human brain networks has become a central focus in neuroscience, particularly in the study of functional connectivity, which plays a crucial role in diagnosing neurological disorders. Advances in functional magnetic resonance imaging and machine learning techniques have significantly improved brain network analysis. However, traditional machine learning approaches struggle to capture the complex relationships between brain regions, while deep learning methods, particularly Transformer-based models, face computational challenges due to their quadratic complexity in long-sequence modeling. To address these limitations, we propose a Core-Periphery State-Space Model (CP-SSM), an innovative framework for functional connectome classification. Specifically, we introduce Mamba, a selective state-space model with linear complexity, to effectively capture long-range dependencies in functional brain networks. Furthermore, inspired by the core-periphery (CP) organization, a fundamental characteristic of brain networks that enhances efficient information transmission, we design CP-MoE, a CP-guided Mixture-of-Experts that improves the representation learning of brain connectivity patterns. We evaluate CP-SSM on two benchmark fMRI datasets: ABIDE and ADNI. Experimental results demonstrate that CP-SSM surpasses Transformer-based models in classification performance while significantly reducing computational complexity. These findings highlight the effectiveness and efficiency of CP-SSM in modeling brain functional connectivity, offering a promising direction for neuroimaging-based neurological disease diagnosis.

Rapid urbanization has significantly escalated traffic congestion, underscoring the need for advanced congestion prediction services to bolster intelligent transportation systems. As one of the world's largest ride-hailing platforms, DiDi places great emphasis on the accuracy of congestion prediction to enhance the effectiveness and reliability of their real-time services, such as travel time estimation and route planning. Despite numerous efforts have been made on congestion prediction, most of them fall short in handling heterogeneous and dynamic spatio-temporal dependencies (e.g., periodic and non-periodic congestions), particularly in the presence of noisy and incomplete traffic data. In this paper, we introduce a Congestion Prediction Mixture-of-Experts, CP-MoE, to address the above challenges. We first propose a sparsely-gated Mixture of Adaptive Graph Learners (MAGLs) with congestion-aware inductive biases to improve the model capacity for efficiently capturing complex spatio-temporal dependencies in varying traffic scenarios. Then, we devise two specialized experts to help identify stable trends and periodic patterns within the traffic data, respectively. By cascading these experts with MAGLs, CP-MoE delivers congestion predictions in a more robust and interpretable manner. Furthermore, an ordinal regression strategy is adopted to facilitate effective collaboration among diverse experts. Extensive experiments on real-world datasets demonstrate the superiority of our proposed method compared with state-of-the-art spatio-temporal prediction models. More importantly, CP-MoE has been deployed in DiDi to improve the accuracy and reliability of the travel time estimation system.