Thenewlyintroduced disentangling paradigm outperforms existing methods by a large margin, with a significant relative mAP gain of9.32% on HICO-Det.

Besides the Scene Flow dataset, we show the depth estimation error on KITTI V al: the 3,769 validation images for 3D object detection.

Probabilistic graphical models use local factors to represent dependence among sets of variables. For many problem domains, for instance climatology and epidemiology, in addition to local dependencies, we may also wish to model heavy-tailed statistics, where extreme deviations should not be treated as outliers. Specifying such distributions using graphical models for probability density functions (PDFs) generally lead to intractable inference and learning. Cumulative distribution networks (CDNs) provide a means to tractably specify multivariate heavy-tailed models as a product of cumulative distribution functions (CDFs). Currently, algorithms for inference and learning, which correspond to computing mixed derivatives, are exact only for tree-structured graphs.

Content delivery networks (CDNs) are the backbone of the Internet and are key in delivering high quality video on demand (VoD), web content and file services to billions of users. CDNs usually consist of hierarchically organized content servers positioned as close to the customers as possible. CDN operators face a significant challenge when analyzing billions of web server and proxy logs generated by their systems. The main objective of this study was to analyze the applicability of various clustering methods in CDN error log analysis. We worked with real-life CDN proxy logs, identified key features included in the logs (e.g., content type, HTTP status code, time-of-day, host) and clustered the log lines corresponding to different host types offering live TV, video on demand, file caching and web content. Our experiments were run on a dataset consisting of proxy logs collected over a 7-day period from a single, physical CDN server running multiple types of services (VoD, live TV, file). The dataset consisted of 2.2 billion log lines. Our analysis showed that CDN error clustering is a viable approach towards identifying recurring errors and improving overall quality of service.

How many times has your website taken a while to load? How many times have you said, "Meh. Your Google page speed score and your core web vitals are more important than ever. Even if you're making sales right now, it's only a matter of time before your competition decides it's better to be the hare and not the tortoise. All of the great content, social media promotion, and keyword research in the world won't matter if your website is a slug on a rainy day.

Content delivery networks (CDNs) provide efficient content distribution over the Internet. CDNs improve the connectivity and efficiency of global communications, but their caching mechanisms may be breached by cyber-attackers. Among the security mechanisms, effective anomaly detection forms an important part of CDN security enhancement. In this work, we propose a multi-perspective unsupervised learning framework for anomaly detection in CDNs. In the proposed framework, a multi-perspective feature engineering approach, an optimized unsupervised anomaly detection model that utilizes an isolation forest and a Gaussian mixture model, and a multi-perspective validation method, are developed to detect abnormal behaviors in CDNs mainly from the client Internet Protocol (IP) and node perspectives, therefore to identify the denial of service (DoS) and cache pollution attack (CPA) patterns. Experimental results are presented based on the analytics of eight days of real-world CDN log data provided by a major CDN operator. Through experiments, the abnormal contents, compromised nodes, malicious IPs, as well as their corresponding attack types, are identified effectively by the proposed framework and validated by multiple cybersecurity experts. This shows the effectiveness of the proposed method when applied to real-world CDN data.

Probabilistic graphical models use local factors to represent dependence among sets of variables. For many problem domains, for instance climatology and epidemiology, in addition to local dependencies, we may also wish to model heavy-tailed statistics, where extreme deviations should not be treated as outliers. Specifying such distributions using graphical models for probability density functions (PDFs) generally lead to intractable inference and learning. Cumulative distribution networks (CDNs) provide a means to tractably specify multivariate heavy-tailed models as a product of cumulative distribution functions (CDFs). Currently, algorithms for inference and learning, which correspond to computing mixed derivatives, are exact only for tree-structured graphs.

The first chapter is the Introductory chapter. The second chapter aims to provide an update of the recent advances in the field of rational design of PDE inhibitors. The third chapter includes designing a series of peptidic inhibitors that possessed a substrate transition-state analog and evaluating the structure-activity relationship of the designed inhibitors, based on docking and scoring, using the docking simulation software Molecular Operating Environment. The aim of the forth chapter is to develop structure-property relationships for the qualitative and quantitative prediction of the reverse-phase liquid chromatographic retention times of chlorogenic acids.

Despite the huge success of deep neural networks (NNs), finding good mechanisms for quantifying their prediction uncertainty is still an open problem. Bayesian neural networks are one of the most popular approaches to uncertainty quantification. On the other hand, it was recently shown that ensembles of NNs, which belong to the class of mixture models, can be used to quantify prediction uncertainty. In this paper, we build upon these two approaches. First, we increase the mixture model's flexibility by replacing the fixed mixing weights by an adaptive, input-dependent distribution (specifying the probability of each component) represented by NNs, and by considering uncountably many mixture components. The resulting class of models can be seen as the continuous counterpart to mixture density networks and is therefore referred to as compound density networks (CDNs). We employ both maximum likelihood and variational Bayesian inference to train CDNs, and empirically show that they yield better uncertainty estimates on out-of-distribution data and are more robust to adversarial examples than the previous approaches.

Picture a world where machines (advanced analytics systems) predict bottlenecks for humans and route traffic to its most appropriate CDN and optimal proxy. This is not far from being true. Let's take an example of a self-driving car. With the help of algorithms and sensors, a self driving car lowers the rate of accidents and gives us more time for ourselves and enables us to just relax during the ride. What happens when thousands of people have self driving cars?