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Japan to ban cannabis ingredient CBN from June

The Japan Times

Starting in June, the health ministry will ban the manufacturing, sale, possession and use of the cannabis-derived compound cannabinol (CBN). Japan's health ministry is set to ban the production, sale, possession and use of cannabinol, or CBN, an ingredient derived from cannabis, from June. An animal experiment conducted following reports of apparent health hazards associated with CBN has found that the substance is highly likely to cause symptoms such as hallucinations. The ministry will regulate CBN as a designated drug under the pharmaceutical and medical devices law through a revision of a relevant ordinance. The amended ordinance is set to take effect in June. In a time of both misinformation and too much information, quality journalism is more crucial than ever.


Intervention and Conditioning in Causal Bayesian Networks

Neural Information Processing Systems

Causal models are crucial for understanding complex systems and identifying causal relationships among variables. Even though causal models are extremely popular, conditional probability calculation of formulas involving interventions pose significant challenges. In case of Causal Bayesian Networks (CBNs), Pearl assumes autonomy of mechanisms that determine interventions to calculate a range of probabilities. We show that by making simple yet often realistic independence assumptions, it is possible to uniquely estimate the probability of an interventional formula (including the well-studied notions of probability of sufficiency and necessity). We discuss when these assumptions are appropriate. Importantly, in many cases of interest, when the assumptions are appropriate, these probability estimates can be evaluated using observational data, which carries immense significance in scenarios where conducting experiments is impractical or unfeasible.






Intervention and Conditioning in Causal Bayesian Networks

Neural Information Processing Systems

Causal models are crucial for understanding complex systems and identifying causal relationships among variables. Even though causal models are extremely popular, conditional probability calculation of formulas involving interventions pose significant challenges. In case of Causal Bayesian Networks (CBNs), Pearl assumes autonomy of mechanisms that determine interventions to calculate a range of probabilities. We show that by making simple yet often realistic independence assumptions, it is possible to uniquely estimate the probability of an interventional formula (including the well-studied notions of probability of sufficiency and necessity). We discuss when these assumptions are appropriate. Importantly, in many cases of interest, when the assumptions are appropriate, these probability estimates can be evaluated using observational data, which carries immense significance in scenarios where conducting experiments is impractical or unfeasible.



Causal Bayesian Networks for Data-driven Safety Analysis of Complex Systems

arXiv.org Artificial Intelligence

Ensuring safe operation of safety-critical complex systems interacting with their environment poses significant challenges, particularly when the system's world model relies on machine learning algorithms to process the perception input. A comprehensive safety argumentation requires knowledge of how faults or functional insufficiencies propagate through the system and interact with external factors, to manage their safety impact. While statistical analysis approaches can support the safety assessment, associative reasoning alone is neither sufficient for the safety argumentation nor for the identification and investigation of safety measures. A causal understanding of the system and its interaction with the environment is crucial for safeguarding safety-critical complex systems. It allows to transfer and generalize knowledge, such as insights gained from testing, and facilitates the identification of potential improvements. This work explores using causal Bayesian networks to model the system's causalities for safety analysis, and proposes measures to assess causal influences based on Pearl's framework of causal inference. We compare the approach of causal Bayesian networks to the well-established fault tree analysis, outlining advantages and limitations. In particular, we examine importance metrics typically employed in fault tree analysis as foundation to discuss suitable causal metrics. An evaluation is performed on the example of a perception system for automated driving. Overall, this work presents an approach for causal reasoning in safety analysis that enables the integration of data-driven and expert-based knowledge to account for uncertainties arising from complex systems operating in open environments.


Disruptive Transformation of Artworks in Master-Disciple Relationships: The Case of Ukiyo-e Artworks

arXiv.org Artificial Intelligence

Artwork research has long relied on human sensibility and subjective judgment, but recent developments in machine learning have enabled the quantitative assessment of features that humans could not discover. In Western paintings, comprehensive analyses have been conducted from various perspectives in conjunction with large databases, but such extensive analysis has not been sufficiently conducted for Eastern paintings. Then, we focus on Ukiyo-e, a traditional Japanese art form, as a case study of Eastern paintings, and conduct a quantitative analysis of creativity in works of art using 11,000 high-resolution images. This involves using the concept of calculating creativity from networks to analyze both the creativity of the artwork and that of the artists. As a result, In terms of Ukiyo-e as a whole, it was found that the creativity of its appearance has declined with the maturation of culture, but in terms of style, it has become more segmented with the maturation of culture and has maintained a high level of creativity. This not only provides new insights into the study of Ukiyo-e but also shows how Ukiyo-e has evolved within the ongoing cultural history, playing a culturally significant role in the analysis of Eastern art.